Jump to content

Furylfuramide isomerase

From Wikipedia, the free encyclopedia
furylfuramide isomerase
Identifiers
EC no.5.2.1.6
CAS no.72561-07-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a furylfuramide isomerase (EC 5.2.1.6) is an enzyme that catalyzes the chemical reaction

(E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide

Hence, this enzyme has one substrate, (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and one product, (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase. It has 2 cofactors: NAD+, and NADH.

References

[edit]
  • Tomoeda M, Kitamura R (1977). "A cis-trans isomerising activity of Escherichia coli. Isomerization from 2-(2-furyl)-3-cis-(5-nitro-2-furyl) acrylamide (furylfuramide) to its trans isomer". Biochim. Biophys. Acta. 480 (1): 315–25. doi:10.1016/0005-2744(77)90344-8. PMID 12827.