From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene .[ 5] [ 6] [ 7]
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis /trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. Two alternatively spliced variants , which encode different isoform , are reported.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000141756 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001555 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Patterson CE, Schaub T, Coleman EJ, Davis EC (Feb 2001). "Developmental Regulation of FKBP65: An ER-localized Extracellular Matrix Binding-Protein" . Mol Biol Cell . 11 (11): 3925–35. doi :10.1091/mbc.11.11.3925 . PMC 15047 PMID 11071917 . ^ Ishikawa Y, Vranka J, Wirz J, Nagata K, Bachinger HP (Nov 2008). "The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens" . J Biol Chem . 283 (46): 31584–90. doi :10.1074/jbc.M802535200 PMID 18786928 . ^ a b "Entrez Gene: FKBP10 FK506 binding protein 10, 65 kDa" .
Patterson CE, Gao J, Rooney AP, Davis EC (2002). "Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family". Genomics . 79 (6): 881–9. doi :10.1006/geno.2002.6777 . PMID 12036304 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol . 21 (6): 660–6. doi :10.1038/nbt827 . PMID 12754519 . S2CID 581283 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries" . DNA Res . 12 (2): 117–26. doi :10.1093/dnares/12.2.117 PMID 16303743 . Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res . 5 (1): 64–75. doi :10.1021/pr0502626 . PMID 16396496 .
Activity Regulation Classification Kinetics Types
