Jump to content

Farnesyl diphosphatase

From Wikipedia, the free encyclopedia
Farnesyl diphosphatase
Identifiers
EC no.3.1.7.6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase.[1][2] It catalyses the reaction

(2E,6E)-farnesyl diphosphate + H2O (2E,6E)-farnesol + diphosphate

The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids.

References

[edit]
  1. ^ Song L (February 2006). "A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol". Applied Biochemistry and Biotechnology. 128 (2): 149–58. doi:10.1385/abab:128:2:149. PMID 16484724.
  2. ^ Tsai SC, Gaylor JL (September 1966). "Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase". The Journal of Biological Chemistry. 241 (17): 4043–50. PMID 4288361.
[edit]