From Wikipedia, the free encyclopedia
Enpiperate
Names
Preferred IUPAC name
1-Methylpiperidin-4-yl hydroxydi(phenyl)acetate
Identifiers
ChemSpider
ECHA InfoCard
100.020.704
UNII
InChI=1S/C20H23NO3/c1-21-14-12-18(13-15-21)24-19(22)20(23,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18,23H,12-15H2,1H3
N Key: UGYPGJCVNPPUPE-UHFFFAOYSA-N
N InChI=1/C20H23NO3/c1-21-14-12-18(13-15-21)24-19(22)20(23,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18,23H,12-15H2,1H3
Key: UGYPGJCVNPPUPE-UHFFFAOYAQ
CN1CCC(CC1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O
Properties
C 20 H 23 N O 3
Molar mass
325.408 g·mol−1
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Enpiperate is a calcium channel blocker .[ 1]
^ Du, Y. L.; Lou, Y. Q. (1989). "Calcium antagonism of enpiperate on isolated rabbit aorta strips and guinea pig ileum". Zhongguo Yao Li Xue Bao . 10 (2): 114–117. PMID 2816410 .
Calcium
VDCCs Tooltip Voltage-dependent calcium channels
Potassium
VGKCs Tooltip Voltage-gated potassium channels
IRKs Tooltip Inwardly rectifying potassium channel
KCa Tooltip Calcium-activated potassium channel
K2Ps Tooltip Tandem pore domain potassium channel
Sodium
VGSCs Tooltip Voltage-gated sodium channels
ENaC Tooltip Epithelial sodium channel
ASICs Tooltip Acid-sensing ion channel
Chloride
CaCCs Tooltip Calcium-activated chloride channel
CFTR Tooltip Cystic fibrosis transmembrane conductance regulator
Unsorted
Others
TRPs Tooltip Transient receptor potential channels LGICs Tooltip Ligand gated ion channels