Draft:William Zamora
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William J. Zamora Ramírez | |
|---|---|
| Born | October 11, 1984 |
| Nationality | Costa Rican |
| Alma mater | University of Barcelona |
| Known for | Lipophilicity scales, Drug discovery, Antimicrobial peptide design |
| Awards | Coimbra Group Scholarship (2021), SAMPL7 Challenge (2021) |
| Scientific career | |
| Fields | Computational chemistry, Chemoinformatics, Computational biology |
| Institutions | University of Costa Rica |
| Doctoral advisor | Prof. F. Javier Luque |
William J. Zamora Ramírez is a Costa Rican researcher, professor, and computational chemist. He is renowned for his contributions to chemoinformatics, computational biology, and drug discovery. Zamora is currently a professor at the University of Costa Rica and leads the Computational Biology and Bioinformatics (CBIO3) Lab. His research focuses on molecular modeling, peptide design, and theoretical studies of biomolecular interactions.
Early Life and Education
[edit]Zamora completed his Ph.D. in computational chemistry at the University of Barcelona, Spain, under the mentorship of Prof. F. Javier Luque. His doctoral research involved the development of pH-dependent lipophilicity scales for amino acids using theoretical models, a contribution published in The Journal of Physical Chemistry Letters.[1]
Career and Research
[edit]Zamora is a professor at the University of Costa Rica and leads the Computational Biology and Bioinformatics (CBIO3) Lab. His research is highly interdisciplinary, focusing on:
- **Lipophilicity Scales**: Developing pH-adapted scales for amino acids to study molecular interactions.[1]
- **Antimicrobial Peptides**: Designing bioactive peptides with therapeutic potential.[2]
- **Drug Discovery**: Applying computational models to predict molecular properties and optimize drug design pipelines.[3]
His work has been published in numerous scientific journals and cited for its impact on computational biology and biophysics. At UCR, Dr. Zamora leads the CBIO3 Lab, which conducts interdisciplinary projects in collaboration with experimental and theoretical chemists, medicinal chemists, computer scientists, biologists, structural biologists, and microbiologists worldwide. His work emphasizes the application of computational methods to understand and design antimicrobial peptides and other bioactive compounds. Dr. Zamora has received several accolades for his contributions to science. In 2021, he was awarded the Coimbra Group Universities Scholarship Programme for Young Professors and Researchers from Latin American Universities, becoming the first Central American to receive this honor. Additionally, he was recognized for his outstanding participation in the SAMPL7 Physical Property Challenge 2021, where his in silico method for determining lipophilicity was deemed the most accurate.
Awards and Recognition
[edit]- **Coimbra Group Scholarship (2021)**: First Central American recipient of this award for young researchers and professors.[4]
- **SAMPL7 Challenge (2021)**: Recognized for the most accurate lipophilicity predictions among international competitors.[3]
- Frequent reviewer for journals such as the Journal of Computer-Aided Molecular Design and FEBS Letters.[5]
Selected Publications
[edit]- Zamora, W. J., Campanera, J. M., & Luque, F. J. (2019). "Development of a Structure-Based, pH-Dependent Lipophilicity Scale of Amino Acids from Continuum Solvation Calculations." The Journal of Physical Chemistry Letters, 10, 883–889. [DOI:10.1021/acs.jpclett.9b00028](https://doi.org/10.1021/acs.jpclett.9b00028).[1]
- Multiple publications on computational biology, antimicrobial peptides, and theoretical chemistry.[5]
References
[edit]- ^ a b c Zamora, William J.; Campanera, Josep M.; Luque, F. Javier (2019). "Development of a Structure-Based, pH-Dependent Lipophilicity Scale of Amino Acids from Continuum Solvation Calculations". The Journal of Physical Chemistry Letters. 10 (4): 883–889. doi:10.1021/acs.jpclett.9b00028. hdl:2445/168798. PMID 30741551.
- ^ "CBIO3 Lab". CBIO3 Lab. Retrieved 2024-11-24.
- ^ a b "SAMPL Challenges". SAMPL Challenges. Retrieved 2024-11-24.
- ^ "Coimbra Group Scholarship 2021". Coimbra Group. Retrieved 2024-11-24.
- ^ a b "CBIO3 Lab". CBIO3 Lab. Retrieved 2024-11-24.
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