Draft:Professor Mark Whiteley

• Comment: Please note we don't use external links in the body of an article. Theroadislong (talk) 15:32, 26 October 2024 (UTC)

• Comment: The editor name, ChloeShephedEditor, and the existence of a PR / content writing agency called Chloe Shepherd and Associates LLC strongly suggests this is a PAID PR job. Until that is cleared up, the article shouldn't be accepted. MarcGarver (talk) 15:20, 26 October 2024 (UTC)

• Comment: For example, the whole section on the clinic reads like an advert. You need to tone down the language to removal the promotional content, cite any claims, etc. In addition, the formatting does not follow normal expectations. Please take a look at some other articles and adjust things like the use of bold and the heading styles accordingly. MarcGarver (talk) 15:15, 26 October 2024 (UTC)

• Comment: Are any of the awards notable? Theroadislong (talk) 17:32, 25 October 2024 (UTC)

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Professor Mark Whiteley
Born	Bristol, South West England
Education	St Bartholomew’s Hospital King Edward’s School, Bath
Occupation	Consultant venous surgeon Executive chairman of The Whiteley Clinic Founder of Whiteley Medical Instruments
Years active	1986 – present
Known for	Completing the first endovenous surgery in the UK. Developing The Whiteley Protocol® to reduce recurrences after varicose veins surgery. Founder of The College of Phlebology. Inventing the TRLOP technique. First to describe the mechanism of successful endovenous ablation “trans-mural death”. Opinion leader in endovenous surgery, pelvic congestion syndrome and aesthetic phlebology.
Awards	See full list

Professor Mark Whiteley is a consultant venous surgeon who has won multiple international and national prizes for his work, and founder of The Whiteley Clinic chain of specialist vein clinics, 6 currently and 2 more opening this year in the UK, which specialises in venous procedures. After completing his medical training in London, he successfully opened his first clinic in 2002 and now has an expanding chain of clinics in the UK specialising in endovenous surgery and offering The Whiteley Protocol®, not just "his own clinic"!

Whiteley is known for completing the first endovenous (non-surgical) keyhole surgery to treat varicose veins in the UK, which was completed in 1999. In 2011, he opened the College of Phlebology. He sits on the editorial board of the Journal of Vascular Surgery Venous and Lympahatic disorders.... and has been a contributing author to multiple international consensus documents in venous surgery.

Early life and education

Whiteley was born in Bristol in 1962 and attended King Edward’s School, Bath, from 1974 – 1981. He then studied at The Medical College of St Bartholomew’s Hospital, as part of the University of London, graduating in 1986, before continuing his training.

Career

Whiteley’s first training appointment was as house surgeon at St. Bartholomew’s Hospital in London, before moving to Homerton Hospital in February 1987. Whiteley stayed in this position until October, when he moved into a temporary lecturer position, teaching human anatomy at The Medical College of St. Bartholomew’s Hospital under Prof OJ Lewis. He then moved to a Senior House Officer position in Accident and Emergency at St. Bartholomew’s and Homerton Hospitals.

Following this, Whiteley began a surgical rotation in Bristol and Weston-super-Mare hospitals, in orthopedic surgery, urology, and vascular surgery. This lasted until July 1990, when Whiteley moved into a registrar in general surgery position at Weston General Hospital. He then began a career registrar rotation around Portsmouth hospitals, where he won the Surgeons-in-Training Medal at the Royal College of Surgeons of Edinburgh for his research into POSSUM and P-POSSUM surgical scoring systems.

Whiteley was appointed to be research fellow and then clinical lecturer (1992-1994) in the Royal United Hospital in Bath, under Professor Michael Horrocks , where he was awarded his Master of Surgery and won the Norman Tanner Medal at the Royal Society of Medicine for his research. He was then appointed as a lecturer in vascular surgery at the University of Oxford 1995-1997 under Prof Sir Peter Morris. Whiteley was appointed as consultant vascular surgeon at The Royal Surrey County Hospital in Guildford in 1998, resigning in 2007 to concentrate solely on venous surgery. In 2013 he was appointed as Visiting Professor to the University of Surrey, resigning in 2020 to take up an Honorary Professorship at The College of Phlebology.

In March 1999, Whiteley performed the first endovenous thermal ablation in the UK. This procedure led to the founding of the Whiteley Clinic

In 2001, Whiteley performed the world’s first endovenous perforator vein closure, using a new technique developed by Whiteley and his colleague, Judith Holdstock, known as TRansLuminal Occlusion of Perforators (TRLOP). This is a pinhole alternative that can be performed under local anesthetic, and under ultrasound guidance. This makes the surgery and recovery time much faster.

This new technique resulted in the development of the VNUS RFS device. After presenting this in America in 2004, US-based vascular surgeons began performing the technique, renaming it Percutaneous Ablation of Perforators (PAPS)

In 2004, Whiteley published a photograph, an ultrasound and a description of a thrombus at the saphenofemoral junction after endovenous ablation with radiofrequency. This was then named Endovenous Heat Induced Thrombosis (EHIT) in 2005

Also in 2004, Whiteley published the first description of the difference between thrombotic occlusion leaving a living “vein wall skeleton” and ablation by transmural death of the vein wall. This difference suggested that the thermoablation process required the transmural death of the vein wall, with lesser injury, resulting in thrombosis and recanalisation. Later, in 2006, Whiteley introduced the idea of a “living skeleton of the vein wall” in a research paper.

In 2019, Whiteley performed the first successful endovenous procedure of the Eco Endovenous Microwave Catheter for varicose veins. Also in 2019, Whiteley successfully performed the first High Intensity Focused Ultrasound (HIFU) Sonovein closure of varicose veins in the UK. This procedure also made him the second doctor to use the system worldwide, and the world’s first commercial case

The Whiteley Clinic

The Whiteley Clinic was founded in 2002, following the success of the UK’s first endovenous (non-surgical) “keyhole” varicose vein operation in March 1999. The revolutionary new operation removed the need to strip the veins from patients, which was often the case in traditional varicose vein surgery, which had various complications such as deep vein thrombosis, pulmonary embolism, and wound complications including infection.

The clinic specialises in the treatment for varicose veins through endovenous surgery. It also offers treatment for venous leg ulcers, aesthetic phlebology, and is a globally leading clinic for pelvic congestion syndrome. It was founded by Professor Whiteley, along with his colleague, Judith Holdstock.

Founded in Guildford, the clinic has further branches in London, Bristol, Poole, Henley-on-Thames and Manchester, as of 2024.

The College of Phlebology

In 2011, Whiteley set up The College of Phlebology after noticing that there was previously no dedicated venous training college in the UK. This was because there was no role in the NHS dedicated solely to venous surgery. Surgeons that perform venous surgeries on the NHS are either specialist vascular surgeons, general surgeons or radiologists.

After years of research, it was found that varicose vein surgery is medical and not cosmetic, as was previously believed by surgeons. The research also brought new, complex technologies to perform endovenous surgeries, creating a requirement to teach these methods. Whiteley saw this requirement and set up the college to train surgeons.

The College of Phlebology runs courses, conferences, and contains a registry of doctors around the world in order to monitor surgeries and results. Conferences are typically held in the UK, with representatives holding conferences internationally, in France and Turkey.

Whiteley Medical Instruments

Whiteley established Whiteley Medical Instruments Ltd in August 2022, as a company to produce medical instruments. The first instrument is due to be released in 2024.

Published works

Whiteley has published over 150 peer-reviewed papers during his career, following the publication of his 1998 thesis, ‘The non-invasive investigation of aorto-iliac arterial disease’.

He has also written five books and contributed over 15 chapters in textbooks. His books are self-published by his company, Whiteley Publishing Ltd, and include:

·          Understanding Venous Reflux – The Cause of Varicose Veins and Venous Leg Ulcers. Published September 2011

·          Advances in Phlebology and Venous Surgery Volume 1. Published December 2017

·          Leg Ulcer Treatment Revolution. Published November 2018

·          Pelvic Congestion Syndrome – Chronic Pelvic Pain and Pelvic Venous Disorders. November 2019

·          Vein Health and Problems in Lockdown and Isolation. December 2020

Latest papers

Parsi K, De Maeseneer M, van Rij AM, Rogan C, Bonython W, Devereux JA, Lekich CK, Amos M, Bozkurt AK, Connor DE, Davies AH, Gianesini S, Gibson K, Gloviczki P, Grabs A, Grillo L, Hafner F, Huber D, Iafrati M, Jackson M, Jindal R, Lim A, Lurie F, Marks L, Raymond-Martimbeau P, Paraskevas P, Ramelet AA, Rial R, Roberts S, Simkin C, Thibault PK, Whiteley MS. Guidelines for management of actual or suspected inadvertent intra-arterial injection of sclerosants. Phlebology. 2024 Jul 24;:2683555241260926. doi: 10.1177/02683555241260926. [Epub ahead of print] PubMed PMID: 39046331.

Bachetta A, Cheung S, Moore ER, Nguyen D, Kiely MJ, Whiteley MS. Defining the Parameters for Endovenous Microwave Ablation to Achieve Equivalence With Endovenous Laser Ablation, Using the Porcine Liver Model. Vasc Endovascular Surg. 2024 Jul;58(5):491-497. doi: 10.1177/15385744241229587. Epub 2024 Jan 19. PubMed PMID: 38240500.

Whiteley MS, Davey SE, Placzek GM. The access and invasiveness-based classification of medical procedures to clarify non-invasive from different forms of minimally invasive and open surgery. Journal of Minimal Access Surgery. 2024 July; 20(3):301. doi: 10.4103/jmas.jmas_240_23.

Strong SM, Cross AC, Sideris M, Whiteley MS. A Retrospective Cohort Study of Patient Risk Factors and Pelvic Venous Reflux Patterns on Treatment Outcomes With Pelvic Vein Embolisation. Vasc Endovascular Surg. 2024 Jun 22;:15385744241264312. doi: 10.1177/15385744241264312. [Epub ahead of print] PubMed PMID: 38907671.

Price BA, Fernandez-Hart TJ, Harrison CC, Holdstock JM, Whiteley MS. Anatomical Classification Of Incompetent Calf Perforator Veins; Ultrasound Analysis Of Over 14,000 Individual Vessels. [preprint]. 2024 May. [30 Pages]. Available from: https://osf.io/preprints/coppreprints/9cyrb. doi: https://doi.org/10.31219/osf.io/9cyrb.

Rivolo M, Teobaldi I, Bellini F, Granata F, Bobbink P, Caniglia A, Clerici G, Corda D, Granara DC, Harikrishna NK, Innocenti L, Lindsay E, Maggio D, Probst S, Ronconi M, Schofield A, Rivellini C, Cassatella R, Hampton S, Whiteley MS, Piazza S. Consensus Conference on Standardizing Terminology for Venous Leg Ulcers: Increasing Clarity and Communication in Clinical Practice. [preprint]. 2024 March. [15 Pages]. Available from: https://osf.io/preprints/coppreprints/5xmfp.

Parsi K, Zhang L, Whiteley MS, Vuong S, Kang M, Naidu N, Grace J, Connor DE. 899 serious adverse events including 13 deaths, 7 strokes, 211 thromboembolic events, and 482 immune reactions: The untold story of cyanoacrylate adhesive closure. Phlebology. 2024 Mar;39(2):80-95. doi: 10.1177/02683555231211086. Epub 2023 Oct 30. PubMed PMID: 37902099.

Whiteley MS, Paone R. Bending and coiling a coated radial endovenous laser fibre does not affect power delivery from the tip – a short report of a pilot study. Version: V1. [preprint]. 2024 February. [16 Pages]. Available from: https://osf.io/preprints/coppreprints/6fhsm. doi: https://doi.org/10.31219/osf.io/6fhsm.

Machin M, Whittley S, Norrie J, Burgess L, Hunt BJ, Bolton L, Shalhoub J, Everington T, Gohel M, Whiteley MS, Rogers S, Onida S, Turner B, Nandhra S, Lawton R, Stephens-Boal A, Singer C, Dunbar J, Carradice D, Davies AH. Evaluating pharmacological THRomboprophylaxis in Individuals undergoing superficial endoVEnous treatment across NHS and private clinics in the UK: a multi-centre, assessor-blind, randomised controlled trial-THRIVE trial. BMJ Open. 2024 Feb 17;14(2):e083488. doi: 10.1136/bmjopen-2023-083488. PubMed PMID: 38367965; PubMed Central PMCID: PMC10875503.

Whiteley MS, Kiely MJ. Syncope (fainting on standing from squatting) due to massive venous reflux into lower limb varicose veins - Case report. SAGE Open Med Case Rep. 2023;11:2050313X231220835. doi: 10.1177/2050313X231220835. eCollection 2023. PubMed PMID: 38130912; PubMed Central PMCID: PMC10734349.

Machin M, Whittley S, Norrie J, Burgess L, Hunt BJ, Bolton-Saghdaoui L, Shalhoub J, Everington T, Gohel M, Whiteley M, Rogers S, Onida S, Turner B, Nandhra S, Lawton R, Stephens-Boal A, Singer C, Dunbar J, Carradice D, Davies AH. THRomboprophylaxis in Individuals undergoing superficial endoVEnous treatment: a multi-centre, assessor blind, randomised controlled trial – THRIVE trial. medRxiv. 2023 December. doi: https://doi.org/10.1101/2023.12.19.23300215.

Whiteley MS, Bruce-Gonzalez AA, Holdstock JM. Endovenous laser ablation of prominent forearm vein – description of a surgical technique. [preprint]. 2023 November. [16 pages]. Available from: https://osf.io/preprints/coppreprints/my5v2/. doi: 10.31219/osf.io/my5v2.

Awards

Event and location	Year	People	Details	Award
European Venous Forum - 2nd Annual Meeting, Rome, Italy	September 2021	MS Whiteley, Fassiadis N, Holdstock JM.	The saphenofemoral valve - gatekeeper turned into rearguard.	3rd prize
11th International Vascular & Endovascular Course (IVEC) and 4th European Congress of the International Society for Vascular Surgery (ISVS) - Milan	October 2010	MS Whiteley, GE Badham, SM Strong	An in Vitro Study to Optimise the Treatment of Varicose Veins with RFiTT	3rd prize
Annual Congress of the American College of Phlebology, Phoenix, Arizona	November 2014	MS Whiteley, CTD Lee, JM Li	Mechanochemical Ablation (MOCA®) Increases Endothelial Damage and Penetration of Damage into the Media Layer of the Vein Wall Compared to Sclerotherapy Alone – A Study Using Histology and Immunohistochemistry	Bronze Abstract Award (3rd Place)
Charing Cross International Symposium – London	April 2015	MS Whiteley, P Diwakar, D Beckett, JM Holdstock, CS Harrison	The Role of Intra-Operative Transvaginal Duplex Ultrasound during Pelvic Vein Embolisation	CERTIFICATE OF MERIT
30th Annual Congress of the American College of Phlebology, Anaheim, California	November 2016	MS Whiteley, HF Ashpitel, FJ Salguero, W García-Jiménez, RM La Ragione	Potential differences in the ablation of the GSV by 810nm and 1470nm Endovenous Lasers, as shown by histology and immunohistochemistry using a novel method of in-vitro treatment.	Bronze Medal (3rd Prize)
Society for Vascular Surgery 2017 Vascular Annual Meeting, San Diego, California	June 2017	Whiteley M, Proebstle TM, Alm J, Dimitri S, Rasmussen L, Lawson J, Cher D,   Davies A.	The European multicentre cohort study on cyanoacrylate embolisation of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2015 Jan;3(1):2-7. doi:       10.1016/j.jvsv.2014.09.001. Epub 2014 Oct 18.	Journal of Vascular Surgery – Venous and Lympahatic Disorders 2016 Most Highly Cited Article Award.
31st Annual Conference of the American College of Phlebology – Austin, Texas	November 2017	MS Whiteley, JM Holdstock, AM White, D Beckett, TJ Fernandez-Hart, H Ashpitel, JL Nemchand.	Nutcracker Phenomena can be over-diagnosed by duplex ultrasound – left ovarian vein reflux can be the cause of renal vein narrowing rather than an effect of obstructive flow.	1st Prize – Best Research Paper of Conference
31st Annual Conference of the American College of Phlebology – Austin, Texas	November 2017	MS Whiteley, CE Davies, BA Price	Vulval Varicose Veins – Associations with Parity	3rd Prize – Third Best Research Paper of Conference
International Session combined vWin Foundation and American College of Phlebology – Austin, Texas	November 2017	MS Whiteley, H Aspitel, FJ Salguero Bodes, RM La Ragione, J Nemchand	Understanding the interaction of endovenous ablation techniques and the vein      wall - immunohistochemistry reveals short term changes that simple histology cannot.	2nd Prize - Runner up in Poster Presentation Competition
Controversies & Updates in Vascular Surgery (CACVS) – Paris	January 2018	MS Whiteley, EB Dabbs, D Beckett, AM White, JM Holdstock, JL Nemchand.	Left Ovarian Vein Reflux – An Ascending Disease Progression Pattern?	e-poster and presentation: Third Prize
American Venous Forum Annual Meeting – Palm Springs	February 2019	MS Whiteley, CE Davies, EB Dabbs, H Ashpitel, J L Nemchand.	Laser power output from the fibre tip during EVLA is not always what the machine displays.	1st Prize for Best Poster
Pan Arab Interventional Radiology Society Conference - Dubai	March 2019	MS Whiteley, D Beckett, JM Holdstock, AM White, TJ Fernandez-Hart.	Does left ovarian vein reflux cause a pseudo-and Nutcracker effect creating meso-aortic narrowing of the left renal vein?	2nd Prize for Best Presentation
American Vein and Lymphatic Society (AVLS) – Phoenix, Arizona	November 2019	Mark Whiteley, Tim J Fernandez-Hart, Angie White, Emma Budd, Omar Abu-Bakr	High Intensity Focused Ultrasound (HIFU) in the Treatment of Incompetent Superficial Veins and Perforating Veins – a Report of our Early Experience	2nd Prize for Best International Presentation
MEDX Xelerator Vascular Challenge 2020 – International Competition for new vascular devices	December 2020	Mark S Whiteley	Novel Catheter Based Non-Thermal Endovenous Ablation Device – Primarily for pelvic venous reflux
American Vein and Lymphatic Society (AVLS)	October 2021	Mark S Whiteley, Amy C Cross, Katherine Walker, Emma A. Borkowski, Laura Setyo, Roberto M La Ragione.	Comparison of the effects of detergent and osmotic sclerosants in an ex-vivo human vein study using histology and immunohistochemistry.	1st Prize for Best Paper presented by a Trainee in Conference
Hiroshi Miyake Award – IMAP XI – Brazil	December 2023	Mark S Whiteley	New insights into success and failure of Venous Ablation with Sonovein (HIFU)
Aesculap/Down's/Surgery Innovation Award	1990	MS Whiteley Surgery 1991, Number 91, p 2171‑2172	Depth Specific Cone Biopsy Instrument	3rd Prize
Section of Surgery, Royal Society of Medicine	February 1995	MS Whiteley, AD Fox, R Harris, M Horrocks	Iso-osmotic bowel preparation improves the accuracy of iliac artery colour flow Duplex examination	NORMAN TANNER MEDAL AND PRIZE
Royal College of Surgeons of Edinburgh	May 1996	MS Whiteley, DR Prytherch, B Higgins, PC Weaver, WG Prout	POSSUM and P-POSSUM for predicting mortality - results from 10,000 surgical patients.	SURGEON-IN-TRAINING MEDAL
Royal Society of Medicine, Surgical Division – Guildford	September 2001	MS Whiteley, L Browning	Deep Vein Reconstruction of an Infected Aortic Graft.	PRIZE FOR BEST PRESENTATION
Society of Vascular Technologists, Annual General Meeting – Belfast	November 2002	MS Whiteley, A.G. MacKinnon, A Clarke, C Smith, JM Holdstock, BA Price.	Superficial Femoral Vein Velocities using currently available products aimed at reducing Venous Thrombo-Embolism (VTE) during air travel.	PRIZE FOR BEST PAPER
Vascular Surgical Society of GB & I (VSSGBI) - Harrogate	November 2004	Whiteley MS, Kianifard B, Holdstock J, Allan C, Smith C, Price B.	Perforator Veins Do Not Remain Closed Following Long Saphenous Vein Stripping – Results Of A Randomised Trial With A One Year Follow Up.	VENOUS FORUM PRIZE
Society of Vascular Technologists, Annual General Meeting – Edinburgh	November 2006	MS Whiteley, JM Holdstock, C Harrison, C Smith, P Marsh, BA Price, CL McGuinness, AJ Lopez.	Prevalence of Pelvic Vein Reflux in Female Patients Presenting with Leg Varicose Veins	PRIZE FOR BEST PAPER
Annual Spring Meeting of the Venous Forum of The Royal Society of Medicine – Bristol	March 2007	MS Whiteley, JM Holdstock, CC Harrison, C Smith, P Marsh, CL McGuinness, BA Price	Is it possible to damage a laser fibre during delivery of tumescent anaesthesia for endovenous laser ablation (EVLA)?	PRIZE – Second place for best paper
Annual Spring Meeting of the Venous Forum of The Royal Society of Medicine – London	April 2013	MS Whiteley , DC Taylor, AM Whiteley, TJ Fernandez-Hart.	Ten Year Results of Radiofrequency Ablation (VNUS Closure®) of the Great Saphenous and Anterior Accessory Saphenous Veins, in the Treatment of Varicose Veins	PRIZE – Best poster
Venous Forum Annual Spring Meeting, Royal Society of Medicine – London	April 2014	MS Whiteley, SB Patel, AE Ostler, SJ Santos, TM Pirie.	The Effects of Altitude, Temperature, Gas to Sclerosant Ratio, Air vs. 50:50 Mixture of CO2 and O2, Foam Volume, Presence of Silicone and Consecutive Uses of Syringes on the Longevity of Tessari-made Foam for Sclerotherapy	FIRST PRIZE
Venous Forum Annual Spring Meeting, Royal Society of Medicine – London	May 2015	MS Whiteley, H. Ashpitel	Analysis of the biological effect of the 1920nm laser on the great saphenous vein wall, using immunohistochemical analysis of the expression of VCAM-1 and p-P53, when treated with various LEEDs.	FIRST PRIZE
Society Vascular Technologists (SVT) Annual General Meeting at the Vascular Surgical Society of Great Britain and Ireland (VSSGBI) - Manchester	November 2019	MS Whiteley, AM White, T Fernandez-Hart, E Budd, O Abu-Bakr	The role of ultrasound and the vascular technologist in high intensity focused Ultrasound (HIFU) treatment for venous incompetence.	FIRST PRIZE
British Society of Gynaecological Endoscopy Annual Scientific Meeting (BSGE ASM) 2022 - Birmingham	April 2022	Mark Whiteley, Sophie Strong, Amy Cross, Michail Sideris.	Pelvic congestion syndrome affects nulliparous and postmenopausal women, and treatment of internal iliac vein reflux is critical: a retrospective cohort study looking at the treatment outcomes following pelvic vein embolisation.	Winner of Silver Prize for Oral Presentation at Conference