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D-lyxose ketol-isomerase

From Wikipedia, the free encyclopedia
D-lyxose ketol-isomerase
Identifiers
EC no.5.3.1.15
CAS no.37318-42-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a D-lyxose ketol-isomerase (EC 5.3.1.15) is an enzyme that catalyzes the chemical reaction

D-lyxose D-xylulose

Hence, this enzyme has one substrate, D-lyxose, and one product, D-xylulose.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common use include D-lyxose isomerase, and D-lyxose ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.

Structural studies

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As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1QO2 and 1VZW.

References

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  • ANDERSON RL, ALLISON DP (1965). "Purification and Characterization of D-Lyxose Isomerase". J. Biol. Chem. 240 (6): 2367–72. doi:10.1016/S0021-9258(18)97332-1. PMID 14304839.