Cugbp elav-like family member 6

CELF6
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2DGQ
Identifiers
Aliases	CELF6, BRUNOL6, CUGBP, Elav-like family member 6, CUGBP Elav-like family member 6
External IDs	OMIM: 612681; GeneCards: CELF6; OMA:CELF6 - orthologs
RNA expression pattern
	Top expressed in
	right uterine tube; ; hypothalamus; ; pituitary gland; ; anterior pituitary; ; prefrontal cortex; ; superior frontal gyrus; ; sural nerve; ; Brodmann area 9; ; right lobe of thyroid gland; ; left lobe of thyroid gland;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleic acid binding; RNA binding; mRNA binding;
Cellular component	nucleus; cytoplasm; cytosol; ribonucleoprotein complex;
Biological process	mRNA processing; regulation of alternative mRNA splicing, via spliceosome; mRNA splice site selection;
	Sources:Amigo / QuickGO
Orthologs
	60677
	n/a
	n/a
	n/a
	Q96J87
	n/a
	NM_052840; NM_001172684; NM_001172685
	n/a
	NP_001166155; NP_001166156; NP_443072
	n/a
	Wikidata
View/Edit Human

CUGBP Elav-like family member 6 is a protein that in humans is encoded by the CELF6 gene. ^[2]

Function

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].

References

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CUGBP Elav-like family member 6". Retrieved 2018-04-18.

Function

References

Further reading