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Aquaporin-9

From Wikipedia, the free encyclopedia

AQP9
Identifiers
AliasesAQP9, AQP-9, HsT17287, SSC1, T17287, aquaporin 9
External IDsOMIM: 602914; MGI: 1891066; HomoloGene: 41405; GeneCards: AQP9; OMA:AQP9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020980
NM_001320635
NM_001320636

NM_001271843
NM_022026

RefSeq (protein)

NP_001307564
NP_001307565
NP_066190

NP_001258772
NP_071309

Location (UCSC)Chr 15: 58.14 – 58.19 MbChr 9: 71.02 – 71.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene.[5]

The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin-9 has greater sequence similarity with AQP3 and AQP7 and they may be a subfamily. Aquaporin-9 allows passage of a wide variety of noncharged solutes. AQP-9 stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. Aquaporin-9 may also have some role in specialized leukocyte functions such as immunological response and bactericidal activity.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000103569Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032204Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: AQP9 aquaporin 9".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.