Anethole trithione

Anethole trithione
Clinical data
ATC code	A16AX02 (WHO) ;
Identifiers
	IUPAC name 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione;
CAS Number	532-11-6 ;
PubChem CID	2194;
DrugBank	DB13853 ;
ChemSpider	2109 ;
UNII	QUY32964DJ;
KEGG	D01584 ;
ChEMBL	ChEMBL178862 ;
CompTox Dashboard (EPA)	DTXSID9046651 ;
ECHA InfoCard	100.007.754
Chemical and physical data
Formula	C10H8OS3
Molar mass	240.35 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES S=C\2SS/C(c1ccc(OC)cc1)=C/2;
	InChI InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 ; Key:KYLIZBIRMBGUOP-UHFFFAOYSA-N ;
	(verify)

Anethole trithione, anetholtrithione, or anetholtrithion (JAN) is a drug used in the treatment of dry mouth. It is listed in the U.S. National Cancer Institute's Dictionary of Cancer Terms as being studied in the treatment of cancer.^[1] Anethole trithione is an organosulfur compound, specifically, a dithiole-thione derivative.^[2]

Brand names

Felviten
Halpen
Hepasulfol - Franco-Indian Pharmaceuticals
Heporal
Mucinol - Sanofi-Aventis
Sialor - Paladin Laboratories; Pharmascience; Solvay; Zuoz Pharma
Sonicur - Solvay
Sulfarlem - Solvay; Aguettant; Edward Keller; Sanofi-Aventis
Sulfarlem S - EG Labo
Tiopropen
Tiotrifar

References

^ Anetholtrithione entry in the public domain NCI Dictionary of Cancer Terms. Retrieved September 13, 2008.
^ Christen MO (1995). "Anethole dithiolethione: Biochemical considerations". Biothiols Part B: Glutathione and Thioredoxin: Thiols in Signal Transduction and Gene Regulation. Methods in Enzymology. Vol. 252. pp. 316–23. doi:10.1016/0076-6879(95)52034-1. ISBN 9780121821531. PMID 7476368.

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[1] Anetholtrithione entry in the public domain NCI Dictionary of Cancer Terms. Retrieved September 13, 2008.

[Christen_1995-2] Christen MO (1995). "Anethole dithiolethione: Biochemical considerations". Biothiols Part B: Glutathione and Thioredoxin: Thiols in Signal Transduction and Gene Regulation. Methods in Enzymology. Vol. 252. pp. 316–23. doi:10.1016/0076-6879(95)52034-1. ISBN 9780121821531. PMID 7476368.

[1]

[2]

v t e Other alimentary tract and metabolism products (A16)
Amino acids and derivatives	Ademetionine Betaine Carglumic acid Glutamine Levocarnitine Mercaptamine Metreleptin
Enzymes	Amino acids: phenylalanine ammonia-lyase (Pegvaliase) Carbohydrate metabolism: sucrase (Sacrosidase) alpha-glucosidase (Alglucosidase alfa, Avalglucosidase alfa, Cipaglucosidase alfa) Glycolipid/sphingolipid: glucocerebrosidase (Alglucerase Imiglucerase Taliglucerase alfa Velaglucerase alfa) alpha-galactosidase (Agalsidase alfa Agalsidase beta Pegunigalsidase alfa) Glycosaminoglycan: iduronidase (Laronidase) arylsulfatase B (Galsulfase) iduronate-2-sulfatase (Idursulfase) idursulfase beta Lipid: lysosomal lipase (Sebelipase alfa) Phosphate: Asfotase alfa atidarsagene autotemcel cerliponase alfa eladocagene exuparvovec elosulfase alfa olipudase alfa pabinafusp alfa pegzilarginase vestronidase alfa
Other	Anethole trithione Eliglustat Givosiran Glycerol phenylbutyrate Leriglitazone Lumasiran Miglustat Nedosiran Nitisinone Sapropterin Sodium benzoate (+sodium phenylacetate) Sodium phenylbutyrate Teduglutide Trientine Tioctic acid Triheptanoin Uridine triacetate Velmanase alfa Zinc acetate

Brand names

See also

References