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Amflora

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Amflora
EventEH92-527-1
Identifier(s)BPS-25271-9
PlantSolanum tuberosum L.
ModeTransgenesis
MethodInsertion
VectorpHoxwG[1]
DeveloperSvalöf Weibull AB[1]
Trait(s) conferredDecreased amylose production, increased kanamycin resistance
Genes introducedGranule bound starch synthase, neomycin phosphotransferase II

Amflora (also known as EH92-527-1) is a genetically modified potato cultivar developed by BASF Plant Science. "Amflora" potato plants produce pure amylopectin starch that is processed to waxy potato starch. It was approved for industrial applications in the European Union on 2 March 2010 by the European Commission.[2] In January 2012, the potato was withdrawn from the market in the EU.

History

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Originally registered on 5 August 1996, Amflora was developed by geneticist Lennart Erjefält and agronomist Jüri Känno of Svalöf Weibull AB.[1]

After the European Commission's approval of the potato, BASF announced it was going to produce Amflora seed starting in April 2010 in Germany's Western Pomerania (20 ha) and Sweden (80 ha). It also announced it was planting 150 ha in the Czech Republic "for commercial aims with an unnamed partner."[3]

Due to lack of acceptance of GM crops in Europe, BASF Plant Science decided in January 2012 to stop its commercialization activities in Europe and would no longer sell Amflora there, but it would continue seeking regulatory approval for its products in the Americas and Asia.[4]

In 2013, an EU court annulled the approval of BASF's Amflora, saying that the EU Commission broke rules when it approved the potato in 2010.[5]

Biology

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Waxy potato varieties produce two main kinds of potato starch, amylose and amylopectin, the latter of which is most industrially useful. The Amflora potato has been modified to contain antisense RNA against the enzyme that drives synthesis of amylose, namely granule bound starch synthase.[6] This resulting potato almost exclusively produces amylopectin, and thus is more useful for the starch industry.

Industrial applications

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Regular potato starch contains two constituent types of molecules: amylopectin (80 percent), which is more useful as a polymer for industry, and amylose (20 percent) which often creates problems as starch retrogradation, so must be modified with chemical reactions which can be costly.[7]

After two decades of research efforts,[8] BASF's biotechnologists using genetic engineering succeeded in creating a potato, named "Amflora", where the gene responsible for the synthesis of amylose had been turned off, thus the potato is unable to synthesize the less desirable amylose.

Amflora potatoes would be processed and sold as starch to industries that prefer waxy potato starch with only amylopectin. Amflora is intended only for industrial applications such as papermaking and other technical applications.[9] Europe produces more than two million metric tons of natural potato starch a year, and BASF with its Amflora product hoped to enter into this large market.[7]

Other possible uses

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According to The New York Times, BASF has a second application pending for use of Amflora's potato pulp as animal feed.[8]

Political disagreements

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Protests against the Amflora potato

Various environmental organizations, such as Greenpeace, disagreed with the introduction of the Amflora genetically modified potato into the market. The lengthy approval process frustrated some supporters of the potato. A BASF scientist said to The New York Times, "it's hard when you see an innovative product go through the loops again and again. These decisions are not about science but about politics".[8] After the potato was approved, the European Greens political party and the then Italian agricultural minister Luca Zaia criticized the approval.[10] The International Peasant Movement La Via Campesina issued a press release on 8 March 2010 also criticizing the decision.[11]

Reactions by Greek politicians

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After Amflora's licensing by the European Commission on 2 March 2010, the Coalition of the Radical Left's Member of Parliament for the A Thessalonikis prefecture, Tasos Kouvelis, asked the Greek Minister of Agriculture on 3 March 2010 to declare the production of the potato illegal in Greece.[12] On 4 March 2010 Panhellenic Socialist Movement's European Member of Parliament Kriton Arsenis submitted a question at Europarl asking about the consequences of Amflora.[13]

PASOK's MP Maria Damanaki accepted the decision of the European Commission, while Greek Agriculture Minister Katerina Batzeli said the production of Amflora will not be allowed in Greece.[14]

Licensing procedure

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Amflora could not be sold within the European Union without approval, and its licence could only be issued after voting at the Council of Ministers of the European Union with a 74 percent threshold of support. Two rounds of voting were held, first by experts in December 2006 and then by the agricultural ministers in July 2007, but both failed to reach the 74 percent threshold. Although the voting was by secret ballot, The New York Times reported that Amflora was supported by the agricultural ministers of Germany and Belgium, and was opposed by the agricultural ministers of Italy, Ireland, and Austria, while the agricultural ministers of France and Bulgaria abstained from voting.[8]

After a licence was issued on 2 March 2010, BASF announced its intention to ask for approval of more varieties of genetically modified potatoes, such as the "Fortuna" potato.[3]

References

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  1. ^ a b c "Notification for Placing the Potato Clone EH92-527-1, Being Genetically Modified for Increased Content of Amylopectin, on the Market" (PDF). Archived from the original (PDF) on November 22, 2008. Retrieved August 17, 2011.
  2. ^ "European Commission approves Amflora starch potato - BASF - the Chemical Company - Corporate Website". Archived from the original on December 6, 2012. Retrieved March 26, 2010.
  3. ^ a b "GM potatoes: BASF at work". Archived from the original on May 31, 2010. Retrieved March 26, 2010.
  4. ^ James Kanter for The New York Times. January 16, 2012. BASF to Stop Selling Genetically Modified Products in Europe
  5. ^ Dunmore, Charlie (December 13, 2013). "EU court annuls approval of BASF's Amflora GMO potato". Retrieved February 26, 2015.
  6. ^ "GMO compass database". Archived from the original on October 9, 2014. Retrieved October 6, 2014.
  7. ^ a b http://www.basf.com/group/corporate/en/function/conversions:/publish/content/products-and-industries/biotechnology/plant-biotechnology/images/BASF_Plant_Science_Amflora.pdf [dead link‍]
  8. ^ a b c d Rosenthal, Elisabeth (July 24, 2007). "A Genetically Modified Potato, Not for Eating, Is Stirring Some Opposition in Europe". The New York Times.
  9. ^ Tagliabue, John (June 10, 2010). "A Potato Remade for Industry Has Some Swedes Frowning". The New York Times. Retrieved February 26, 2015.
  10. ^ "ΠΑΣΕΓΕΣ: Η Ευρ. Επιτροπή ενέκρινε την καλλιέργεια της μεταλλαγμένης πατάτας Amflora". Archived from the original on July 21, 2011. Retrieved March 27, 2010.
  11. ^ "La Via Campesina | International Peasants' Movement". Via Campesina English. Retrieved April 17, 2023.
  12. ^ "Να απαγορευτεί η καλλιέργεια της μεταλλαγμένης πατάτας Amflora από τους αγρότες της χώρας μας | Τάσος Κουράκης". Archived from the original on August 29, 2016. Retrieved July 17, 2011.
  13. ^ "Ενημέρωση".
  14. ^ "Amflora - 4/3/2010 7:00:00". Archived from the original on September 27, 2011.

Further reading

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Wikimedia Commons has media related to Amflora.
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