Zinc finger protein 717

ZNF717
Identifiers
Aliases	ZNF717, X17, ZNF838, zinc finger protein 717, OB1
External IDs	OMIM: 618405; MGI: 99183; HomoloGene: 69102; GeneCards: ZNF717; OMA:ZNF717 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	75,785,583 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	58,795,051 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; right uterine tube; ; body of pancreas; ; anterior pituitary; ; skin of abdomen; ; mucosa of ileum; ; skin of leg; ; body of stomach; ; secondary oocyte;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; Rostral migratory stream; ; cumulus cell; ; genital tubercle; ; sciatic nerve; ; Paneth cell; ; tail of embryo; ; primitive streak;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	100131827
	22698
	ENSG00000227124
	ENSMUSG00000037001
	Q9BY31
	Q02525
NM_001128223; NM_001290208; NM_001290209; NM_001290210; NM_001324026;
	NM_001324027; NM_001324028
	NM_011758
NP_001121695; NP_001277137; NP_001277138; NP_001277139; NP_001310955;
	NP_001310956; NP_001310957
	NP_035888
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 717 is a protein that in humans is encoded by the ZNF717 gene.^[5]

Function

This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000227124 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037001 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 717". Retrieved 2017-04-01.

Function

References

Further reading