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X-Trp aminopeptidase

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Xaa-Trp aminopeptidase
Identifiers
EC no.3.4.11.16
CAS no.137010-33-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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NCBIproteins

Xaa-Trp aminopeptidase (EC 3.4.11.16, aminopeptidase W, aminopeptidase X-Trp) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Release of a variety of N-terminal residues (especially glutamate and leucine) from peptides, provided tryptophan (or at least phenylalanine or tyrosine) is the penultimate residue. Also acts on Glu!Trp, Leu!Trp and a number of other dipeptides

This glycoprotein contains Zn2+.

References

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  1. ^ Gee NS, Kenny AJ (September 1985). "Proteins of the kidney microvillar membrane. The 130 kDa protein in pig kidney, recognized by monoclonal antibody GK5C1, is an ectoenzyme with aminopeptidase activity". The Biochemical Journal. 230 (3): 753–64. doi:10.1042/bj2300753. PMC 1152680. PMID 4062876.
  2. ^ Gee NS, Kenny AJ (August 1987). "Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W". The Biochemical Journal. 246 (1): 97–102. doi:10.1042/bj2460097. PMC 1148244. PMID 2890346.
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