Wikipedia:Reference desk/Archives/Science/2023 April 24
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April 24
[edit]What is more epinephrine agonist, tricyclic antidepressants (such as Amitriptyline), or tetracyclic antidepressants (such as Mirtazapine)?
[edit]Thanks. 2A10:8012:15:C48E:4400:7673:DFF0:2D67 (talk) 02:18, 24 April 2023 (UTC)
- I saw one article (PMC 5715313) that states: "
The SSRIs and other atypical antidepressants (eg, trazadone, mirtazapine, bupropion) do not have significant epinephrine or ephedrine interactions (Figure 4).
" In another article specifically about mirtazapine (PMID 30085601), epinephrine is not mentioned in a list of drugs known to interact with mirtazapine. I do not know if this can be generalized to tetracyclic antidepressants in general. --Lambiam 05:58, 24 April 2023 (UTC)