Wikipedia:Reference desk/Archives/Science/2017 March 1
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March 1
[edit]Why is the academic establishment worshipping materialism?
[edit]OP seems to be more interested in an argument than in seeking references so I'm "denying freedom of speech". Nil Einne (talk) 08:59, 1 March 2017 (UTC) |
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The following discussion has been closed. Please do not modify it. |
I've been reading about consciousness for a while and what surprised me was the number of biologists/neuroscientists assuming materialism like a religion. There's no evidence what so ever consciousness can arise out of inanimate matter, yet they worship it like a god, despite their own champions admitting the seemingly impossible problem with consciousness. Daniel Dennett said he'll suicide if materialism turned out to be false, if this is not worship I don't know what is. Of course you'd say "who cares what people think", the problem is any investigation of paranormal does not get funded. We might be on the verge of the biggest revolution in human history but it's severely delayed due to lack of funding. P.S. I know this isn't a forum, just wanna know why the fanatic worship of materialism. — Preceding unsigned comment added by Money is tight (talk • contribs) 04:45, 1 March 2017 (UTC)
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A Tibetan highlander marries an Andean highlander and they get children
[edit]They are both genetically adapted to living at altitude, but in different ways. Does that mean that their children can become much better adapted to living at altitude than either one of their parents? Count Iblis (talk) 08:57, 1 March 2017 (UTC)
- Even assuming any genetic adaptations carry over, the answer is still not necessarily. The adaptations could conflict for example, or simply provide no added benefit over each other. Nil Einne (talk) 09:06, 1 March 2017 (UTC)
- Reading the link above, the known adaptations seem to be a barrel chest (more volume) and more red blood cells, in the case of Andeans, versus wider blood vessels and more frequent breaths, in the case of Himalayans. Those do seem complimentary. Specifically, the additional red blood cells have the downside of thickening the blood and making it flow less well, and the wider blood vessels should fix that. However, a more robust heart is required to pump more blood. StuRat (talk) 13:58, 1 March 2017 (UTC)
- Or, if both happen to be heterozygous for their respective adaptations, there's a 25% chance that their child will inherit neither of their adaptations and will therefore be no better adapted to living at altitude than a normal person. 2601:646:8E01:7E0B:F88D:DE34:7772:8E5B (talk) 09:33, 1 March 2017 (UTC)
- It can be a lot more complicated than that, but yes those complications are why I said "Even assuming any genetic adaptations carry over". Nil Einne (talk) 10:52, 1 March 2017 (UTC)
- As a general principle, when you combine populations with different sets of adaptations, what you get initially is a high level of variability. Some of the offspring are substantially better adapted than the source populations, some worse, many more or less as well. The advantage of combining populations comes if you perform selection on the offspring. By doing that it is often possible within a few generations to get individuals who are a lot better adapted than the source populations. Looie496 (talk) 14:09, 1 March 2017 (UTC)
- Yes, and historically that selection was accomplished by the early deaths of those who were poorly adapted. Another option, in this case, would be to have the children at low altitude, and only move those who are well adapted, to high altitude. Or, better yet, use genetic engineering to only produce offspring with the desired traits. StuRat (talk) 14:13, 1 March 2017 (UTC)
- I'd expect much of this would have to do with dominance (genetics) - some traits will be phenotypically apparent in the F1 hybrid and others will not. The data might exist to look them up one by one and make a guess, though this involves some work.
- Long-term, selection would seem highly relevant -- as StuRat says, some of the people would tend to dislike the high altitude and choose opportunities at lower elevation, while others would feel fine and perhaps excel in the local workplace. That said, it seems potentially faster to work out a means for continuous production, low-pressure storage and ergonomic consumption of oxygen, and perhaps easier to do this than to do safe genetic engineering of the human germline, and such a compensating mechanism also could be more effective than all known adaptations. For example we might connive some kind of hydrophobic oxidizer that is avidly absorbed by some kind of active uptake mechanism at the skin and put into the bloodstream, which then safely releases free oxygen and degrades to a carrier compound; possibly we might even modify some keratinocytes to manufacture the carrier and apply energy to react with oxygen at the skin surface. Such gene therapy need only be skin deep. Wnt (talk) 14:41, 1 March 2017 (UTC)
- Adaptation to elevation is likely not a simple trait with simple dominance, right? Here's a little example of how inheritance of complex traits is weird: Here [1] is a white call duck. Here [2] is one that looks like a mallard. When you breed the two, you might expect to get something like this [3]. But that is not what happens! You will likely get something like this [4], but you won't get the pied/dappled look, not in F1 generation (the mottled mallard look is called "snowy", and it breeds true). Here is a page that outlines some of coat/color dominance relationships [5].
- The point is, we have no a priori knowledge on how the human traits OP asks about will combine (or not), not until we have some actual evidence from offspring. Perhaps an expert in these specific mutations could offer an educated guess, but I'm not optimistic of one showing up ;) SemanticMantis (talk) 15:02, 1 March 2017 (UTC)
- This is true - in biology you never really know what will happen until you do the experiment. The sort of phenomenon you're describing is described at epistasis (gene interaction also lands there) and epistasis and functional genomics. That said, respiration and oxygen uptake seems like such a basic matter of physics that I'm thinking there might be lower-than-average creativity in the adaptations addressing it. Wnt (talk) 15:28, 1 March 2017 (UTC)
- Ah, thanks I forgot the term(s). Pleiotropy is also possible for the altitude adaptations, but maybe not super likely, in light of your reasoning based on a sort of essentialness. SemanticMantis (talk) 15:50, 1 March 2017 (UTC)
- Perhaps such complicated genetics are less likely but for most of the adaptations described, particularly the number of red blood cells, it's not hard to imagine there may be some degree of Additive genetic effects even with a single gene. So since the offspring is only ever going to inherit one allele of the better adapted genes, the F1 generation is going to be less well adapted in that area than their parent but at the same time still better than the second parent (except in that case you'll be the same as the second parent with non of the adaptation of the first parent). Of course there is going be something similar even with recessive traits in a classic dominance system anyway. And even if they aren't as complicated as some of the proposals by SemanticMantis, I'm not convinced the stuff mentioned are going to be single genes so there's a fair chance it will get complicated. As Looie496 mentioned, there may be a fair chance you can eventually get all adaptations for high altitude living, resonably well displayed after a few generations if you properly breed and select but the more loci involved and the more complicated the inheritance of the phenotype, the more complicated this gets. If for some reason the offspring are also interested in achieving this super high altitude adaptee then perhaps you can achieve this, but in practice.... In any case, as I said above even if you can get them perfectly into the phenotype, there's no guarantee these adaptations are going to actually work together to give offspring better adapted to higher altitude. The more assumptions you make about how something should probably work, the more likely you are to be wrong with at least one of them. Nil Einne (talk) 21:22, 1 March 2017 (UTC)
- Ah, thanks I forgot the term(s). Pleiotropy is also possible for the altitude adaptations, but maybe not super likely, in light of your reasoning based on a sort of essentialness. SemanticMantis (talk) 15:50, 1 March 2017 (UTC)
- This is true - in biology you never really know what will happen until you do the experiment. The sort of phenomenon you're describing is described at epistasis (gene interaction also lands there) and epistasis and functional genomics. That said, respiration and oxygen uptake seems like such a basic matter of physics that I'm thinking there might be lower-than-average creativity in the adaptations addressing it. Wnt (talk) 15:28, 1 March 2017 (UTC)
Selling live genetically-modified food animals in UK
[edit]Can people have genetically-modified chickens (e.g. flu resistant egg layers) in the UK if they're for their own use/consumption without having to go through the UK FSA? Would someone be allowed to sell the chickens to people if they were layers laying eggs for consumption? Is this allowed anywhere else in the west? --129.215.47.59 (talk) 16:36, 1 March 2017 (UTC)
- FSA issues aside, although I couldn't actually find the precise regulations* I'm fairly sure such chickens could not be sold or imported to random people anywhere in the EU which currently includes the UK, at least without some sort of rigorous authorisation. Consider GloFish which aren't intended for consumption but are generally accepted as not something which can be easily sold in the EU [6] [7] [8] [9] [10] [11]. If you were a researcher, you could potentially produce or import such chickens under some circumstances but I'm not sure these would allow anyone to eat the eggs, again without going through a rigorous authorisation process. (* = Regulation of genetically modified organisms in the European Union seems to imply it doesn't cover GM animals. That said while [12] & [13] seem to only deal with food & feed issues and don't seem to mention GM animals and do mention crops at places, they also don't seem to specifically restrict the regulations to only dealing with food and feed from plants, at least not that I noticed. In fact one of the first sentences of the FAQ is "Food and feed generally originate from plants and animals grown and bred by humans for several thousands of years".) P.S. Yes I'm aware the PDF refers to copyright when it almost definitely isn't copyright that's involved, still it seems like a decent source at least to confirm GloFish can't be easily sold in the EU. Nil Einne (talk) 00:44, 2 March 2017 (UTC)
- all animals artificially selected by humans for thousands of years are GMO's 64.170.21.194 (talk) 02:22, 4 March 2017 (UTC)