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December 7

Pool Adjusted Risk Ratio

I'm looking into the relation between Benzodiazepines and Dementia. I found in an article: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127836 that "Compared with never users, pooled adjusted risk ratios (RRs) for dementia were 1.49 (95% confidence interval (CI) 1.30–1.72) for ever users" is this the same as the Odds_ratio? Is 1.49 a high figure? In the example in the article the wine drinking variable is highly correlated with men compared to women and has a ration of 36 which would make me think that 1.49 is not that high. What does it mean exactly? --MadScientistX11 (talk) 21:25, 7 December 2018 (UTC)[reply]

From our article Risk ratio:

In epidemiology, risk ratio (RR) or relative risk is the ratio of the probability of an outcome in an exposed group to the probability of an outcome in an unexposed group.

So a risk ratio of 1.49 means that the dementia probability of people exposed to the drug is half again as big as that for people not exposed to the drug. For example, if 10% of unexposed people develop dementia, then 1.49 × 10% = 14.9% of exposed people develop dementia. The risk ratio is very similar to, but not identical to, the odds ratio, which is the ratio of odds rather than of probabilities. 1.49 seems pretty high to me. Loraof (talk) 23:20, 7 December 2018 (UTC)[reply]

Excellent, just what I needed to know. Thanks. --MadScientistX11 (talk) 23:56, 7 December 2018 (UTC)[reply]