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DNA replication

[edit]
Original - DNA replication is the process of copying a double-stranded DNA molecule to form two double-stranded molecules. The process of DNA replication is a fundamental process used by all living organisms as it is the basis for biological inheritance.
Reason
same reasons given in Cell membrane (diagrammatic)
Articles this image appears in
DNA replication, DNA, Replication fork
Creator
Mariana Ruiz
  • Support as nominator --Alokprasad84 (talk) 08:17, 12 June 2008 (UTC)[reply]
  • Question Oppose Do single strand binding proteins sit on the leading strand? I thought not because the helicase and polymerase were complexed there. de Bivort 14:57, 12 June 2008 (UTC)[reply]
    • Single-strand binding proteins bind with both of single stranded DNA, leading strand as well as lagging strand templates during replication.Alokprasad84 (talk) 16:29, 12 June 2008 (UTC)[reply]
      • Alberts et al makes no mention of SSBP on the leading strand (search for SSB). And there is lots of evidence that helicase and polymerase directly interact on the leading strand (e.g. [1]). SO, I'm switching to oppose because this is not shown accurately. de Bivort 19:56, 12 June 2008 (UTC)[reply]
        • Clarification- Hi Bivort. I am glad to respond your concern. Actually SSBs are one of the proteins which function is to prevent denatured dna to reanneal after unwinded by helicase enzyme. Helicase only interact with dsDNA and it play to stabilise sDNA at the near dsDNA region only. and you know plymerase react wint sDNA near growing point. Alberts et al have not mentioned clearly about SSBs in detail. If you want to know more go through some respected books like Biochemistry by Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, Molecular Biology of thw Gene by James D. Watson et al, The Cell A Molecular Approach by Geoffrey M. Cooper. if you want more clarification dont hesitate. thank you...Alokprasad84 (talk) 07:33, 13 June 2008 (UTC)[reply]
          • Well those images could represent a clarification - but I think images such as 1 2 and 3 4 are more useful. They have greater accuracy in at least showing the polymerases coupled to the helicases to form the replisome - and none of them show SSBPs on the leading strand - in fact, every diagram I have found which does show SSBPs on the leading strand does not show polymerases and helicases physically interacting - which we know the do. de Bivort 20:19, 13 June 2008 (UTC)[reply]
            • you are talking about replisome mechanism of dna replication. here i am not talking about any mechnism, this image is not for representing any mechnism, but is for giving basic information about how dna reproduce itself. even replisome mechanism is not exactlly represents dna repilication, exact mechanism is still matter of research. But I am not want to divert dicussion towards technachality of process. please provide me some refrances (not picture) which claiming no role of RPA (SSBs) on leading strand in any mechanism of dna replication. i have gone through some standered books and research papers no one claims negative role of RPA on leading strand. Alokprasad84 (talk) 08:51, 15 June 2008 (UTC)[reply]
  • Oppose unless there are reference for verifiability. LadyOfHats makes great SVGs but they need some sourcing so that they can be verified for use in articles. SVG diagrams need that. gren グレン 21:16, 14 June 2008 (UTC)[reply]
  • Oppose First, I don't believe in nominating pure photoshop candidates. Secondly, i've seen similar images many times in some of my bio books, and do not think this illustration is unique enough to warrant a Featured Picture status. smooth0707 (talk) 02:06, 15 June 2008 (UTC)[reply]
  • This is almost certainly Illustrator, not Photoshop. But more importantly, nothing in the Featured Picture Criteria says "pure photoshop candidates" should be excluded. As for your second point, you need to evaluate the question of whether the image is the best Wikipedia has to offer. Not whether it is the best all collective literature has to offer. de Bivort 05:27, 15 June 2008 (UTC)[reply]
  • here i agree with Bivort. this is not photoshop candidate, its purely a Illustrator. certainly You (Smooth0707) have seen this image in various books. But question is that what should be featured? Wiki Featured Picture Criteria is not saying that pictured to be featured should be unique and exclusive then only be given featured status. rather it should be good quality, adding value to article etc. Please clear your (smooth0707) stand.Alokprasad84 (talk) 09:09, 15 June 2008 (UTC)[reply]
  • I just don't think that this image is one of the finest on the English Wiki, and what I meant by "unique," is that this arguably common image doesn't make me want to read the accompanying article like some of the Featured candidates. An informative image nonetheless. smooth0707 (talk) 16:42, 16 June 2008 (UTC)[reply]
  • Weak oppose Besides citation and accuracy concerns, lacks 'wow factor'. Perhaps just a result of the subject matter (still under research) but everything - polymerase, helicase, primase & binding proteins all lack detail and interest for the viewer. Dhatfield (talk) 17:15, 16 June 2008 (UTC)[reply]

Not promoted . --John254 01:55, 18 June 2008 (UTC)[reply]

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