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VAMP5

From Wikipedia, the free encyclopedia
vesicle-associated membrane protein 5 (myobrevin)
Identifiers
SymbolVAMP5
NCBI gene10791
HGNC12646
OMIM607029
RefSeqNM_006634
UniProtO95183
Other data
LocusChr. 2 p11.2
Search for
StructuresSwiss-model
DomainsInterPro

Vesicle-associated membrane protein 5 (VAMP-5) is a synaptobrevin protein encoded in the human by the VAMP5 gene.[1][2]

Function

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VAMPs (synaptobrevins) along with syntaxins and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.[2]

References

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  1. ^ Zeng Q, Subramaniam VN, Wong SH, Tang BL, Parton RG, Rea S, James DE, Hong W (September 1998). "A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane". Molecular Biology of the Cell. 9 (9): 2423–37. doi:10.1091/mbc.9.9.2423. PMC 25509. PMID 9725904.
  2. ^ a b "Entrez Gene: STX12 syntaxin 12".
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.