Uterine hyperstimulation
Uterine hyperstimulation or hypertonic uterine dysfunction is a potential complication of labor induction. This is displayed as Uterine tachysystole- the contraction frequency numbering more than five in a 10-minute time frame or as contractions exceeding more than two minutes in duration.[1] Uterine hyperstimulation may result in fetal heart rate abnormalities, uterine rupture, or placental abruption. It is usually treated by administering terbutaline.[2]
Causes
[edit]- Mistoprostol is a drug treatment for peptic ulcers that can also cause abortion or induce labor. The use of this drug (inserted vaginally) to induce labor can cause uterine hyperstimulation.
Treatment
[edit]Treatments of uterine hyperstimulation are primarily experimental. Those that have shown to alleviate the conditions are:
- Prostoglandin E2 is administered before labor to minimize risk of uterine hyperstimulation and to minimize the effects on Fetal Heart Rate.
- Administration of tocolytic treatment with β2-adrenergic drugs has shown to stabilize uterine contractions while also effectively lowering Fetal Heart Rate.
- The usage of a balloon catheter to induce labor rather than Prostoglandin E2 lowers the risk of uterine hyperstimulation and its effect on fetal heart rate.
References
[edit]- ^ Briggs GG, Wan SR (June 2006). "Drug therapy during labor and delivery, part 2". Am J Health Syst Pharm. 63 (12): 1131–9. doi:10.2146/ajhp050265.p2. PMID 16754739. Retrieved 2009-08-03., which cites:
- American College of Obstetricians and Gynecologists (December 1999). "Induction of labor". ACOG Practice Bulletin. 10. Washington, DC.
- ^ Briggs GG, Wan SR (June 2006). "Drug therapy during labor and delivery, part 2". Am J Health Syst Pharm. 63 (12): 1131–9. doi:10.2146/ajhp050265.p2. PMID 16754739. Retrieved 2009-08-03.
- National Collaborating Centre for Women's and Children's Health (UK). Induction of Labour. London: RCOG Press; 2008 Jul. (NICE Clinical Guidelines, No. 70.) 8, Complications of induction of labour.
- Jeroen Bosch Hospital, Department of Obstetrics, et al. “Mechanical Methods for Induction of Labor.” US National Public Library, 18 Oct. 2019. PMC 6953206
- H. Dadi S.C. Patwardhan A. Ikomi D. Ojutiku, "Self‐induction of labour using misoprostol: an unusual case of uterine hyperstimulation". doi:10.1111/j.1471-0528.2004.00186.x
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