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bibliomaniac 1 5 22:16, 20 December 2006 (UTC)[reply]

Sinusitis & biofilms

Hi, interesting stuff you have been adding to sinusitis, yes I should have parsed the text through a spell-checker when I worked on the styling and the refs - so many thanks. However your most recent editions really are more about biofilms than specifically their relevance to sinusitis. Could you consider moving this across to biofilms (otherwise it is likely to be reverted as being off-topic)? David Ruben ^Talk 01:26, 21 December 2006 (UTC)[reply]

David: I am a metallurgest. I had a pretty good idea that I was seeing a typical biofilm when I looked at specimans from my own sinuses, but what I see is not persuasive because I am not a specialist in the medical feild. Thus I wrote to different people in the the NIH for 3 years asking them to fund studies to inspect tissue removed from sinus surgery for biofilms. When the removed tissue was inspected, the overwhelming majority of CS surgery patients had a biofilm infection, but the medical community at large has no test protocol to detect it. The governing paradigm within the oralangyeal community is that if it cultures are negative and treatment with antibiotics fails, then the condition is autoimmune, or paradoxically an immune deficient condition. Only a well-documented test that puts biofilm detection within the abilities of the clinician will allow patients with biofilm sinusitis to be diagnosed as having an infection rather than an allergy, and receive more effective treatment. Therefore the discussion of biofilms is not only on topic, but it is not hard to see how it will be potentially helpful to sinus suffers if the word gets out sooner rather than later.````

AMA

Hi I'm the AMA advocate you contacted, I wonder if you could give me a little more information about the specifics of your conflcit and the other wikipedia users this dispute invovles. --Gary123 16:20, 26 December 2006 (UTC)[reply]

I'm still not 100% clear on the technicalities of your problem but if you'd give me the name of the users your having trouble with I'll send them a message and try to get their POV. If the two of you can't reach a consensus then I would suggest at that point formally requesting an AMA case. --Gary123 04:23, 27 December 2006 (UTC)[reply]

Sinusitis Biofilm Edits

The sum total of your edits gives a factually incorrect impression. I believe it so reduces the presentation of the subject matter that it constructively violates NPO. The only time that biofilms have not been found in tissue removed from patients with CS is when the mateial was not examined for them. Once you know what you are looking at, were you to do either freeze fracture samples or use a confocal microscope and the approperate stains, you would see them.

Almost ALL important pathogens form biofilms.

The fact that it may take a Grassley Act law suit to get medical schools to pay attention to how real "wild type" bacteria grow is just really really sad.

Plese reply by e-mail or on my talk page, which you guys did not bother to do when you made these edits. Truehawk 21:37, 4 May 2007 (UTC)[reply]

Actually, a number of people have responded to your edits on the article talk page, which is the most appropriate location for such discussion. Regarding NPOV, it might be useful to re-read the section of the policy dealing with undue weight, which has been brought up regarding your edits on the article talk page. MastCell ^Talk 22:05, 4 May 2007 (UTC)[reply]

The number of people responding to my edits, if I remember, was David Rubin, who has in the past e-mailed me when he was going to edit, Rustavo, and you MastCell. This is a more approperate venue for what I have to say to you, as you if I remember correctly said that there was no section about biofilms in your infectious disease textbook. There is not. Now WHY??

I am a metallurgist. Don't you think that it is preculiar that the vet, the waste water scientist and I know more about biofilms than you do?

Do you think that approperate or desirable?

And why is MastCell responding on Rustavo's page? Truehawk 23:54, 4 May 2007 (UTC)[reply]

It is possible that you are right, and that the medical community has greatly underappreciated the role of biofilms in chronic sinusitis. However, Wikipedia is not the forum in which to make an original argument to that effect. There are plenty of other forums in which it would be more appropriate for to write at length about your personal theories regarding biofilms (might I suggest a free webhosting service?). One could synthesize any number of theories about the significance of the presence of biofilms on the mucosa of chronic sinusitis patients - they could be present as the result of an underlying immune deficiency, or they could be commensal organisms which are not harmful, but are able to grow on mucosa which has been damaged by previous inflammatory episodes from a completely different cause. In the absence of reliable published sources which directly discuss these hypotheses, it's not appropriate for any of us to inject our own favored one into the article.

Regarding your other concern, I assumed that since you had posted dozens of times on Talk:Sinusitis, you would continue to follow the discussion there. Since several commentators seemed to agree that your edits were not in line with basic rules about content on Wikipedia, I felt confortable proceeding with the changes. I'll copy this conversation to your talk page to ensure that you read it.-Rustavo^{Talk/Contribs} 04:09, 5 May 2007 (UTC)[reply]

Per your kindly phrased request, I have read a review article on biofilms in chronic sinusitis by James Palmer and made appropriate changes to the biofilm section of Sinusitis. Please refer to my comments on Talk:Sinusitis.-Rustavo^{Talk/Contribs} 05:21, 5 May 2007 (UTC)[reply]

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