User talk:Lipei12/sandbox

Hi Lipei12,

After reading a little bit about your fungus, I have discovered that it is also a plant pathogen! After looking through your sandbox, I think it would be worth mentioning this fact perhaps a little earlier on. In addition, maybe mentioning how it causes disease would be interesting! What is it about the plant that makes it a good host for this fungus? Remember how we discussed Alternaria in class? Is there a life-cycle diagram you could include in this page? In addition, considering this also causes human disease, do you think that it may potentially harbor any allergens? What about any known mycotoxins? Furthermore, since this is a fungus in the ascomycota, there is a high chance that it could be mouldy! Did you look into this?

You also mention that it is found in soils. Do you think it forms any Mycorrhizal associations with plants? Perhaps some discussed in class like Ectomycorhizzae or Vesicular arbuscular mycorrhiza? There could be something that we didn’t discuss in class at all out there! I think that would be interesting to include! If not I think it may be worth mentioning that even though it lives in the soil, it does not have any symbiotic associations with plant roots.

To add, I suggest that you attempt to shorten some of your sentences. While I can understand that there are many important and fascinating features to this fungus, reading a sentence that is 2-3 lines long made it a little difficult for me to follow.

I also caught a typing error under the subheading pathogenicity, perhaps you should change the following sentence to”pulmonary colonization in children" with cystic fibrosis, and disseminated infection…”

In addition, I would have liked to read about what the diagnosis of these clinical cases were. Do we know whether or not people survive this? Are there any early signs or symptoms we could use to identify a possible infection? Furthermore, how did the clinicians elucidate that this was the fungus at hand? Do you know if there are any special metabolic properties this fungus has that allows it to convert certain media into different colours or produce certain metabolites that can help identify this fungus?

Lastly, I believe that having a nice picture of the fungus on the top of your page will definitely add to the appeal of the page! Try asking the professors for some help as I know you can only use certain sources for images in Wikipedia!

Otherwise, I am excited to see how this turns out!

Halatamim (talk) 14:29, 27 October 2016 (UTC)[reply]

Hi there,

I ran your fungus through Web of Science and PubMed and got a bunch of articles referencing the prominence of this fungi to cystic fibrosis, a good point to expand on for the pathogenicity of the fungi (as you only have a little point at the end relating it to CF incidence in children).

Airway Colonization by Acrophialophora fusispora in Patients with Cystic Fibrosis by Cimon B. et al. (2005) (has a bunch of case studies referring to this)

I also found two other articles referencing A. fusispora brain abscesses in immunocompromised people, in a child with lymphoblastic leukemia and a patient with AIDS.

Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature (2013) by Li CW et al. Acrophialophora fusispora brain abscess in a child with acute lymphoblastic leukemia: Review of cases and taxonomy (2000) by Al-Mohsen IZ et al. (both I found on Web of Science)

Lastly, I also found an article referring to the misidentification of your fungus as another, which might be of some interest?

Acrophialophora fusispora Misidentified as Scedosporium prolificans (2002) by Guarro J. and Gené J. (my search produced two of these articles under different authors, but the same name)

Besides the pathogenicity, I think you have a good coverage of the ecology and physiology of your fungus, though some portions within your text should be edited for flow (like the line that mentions the conidiophores, you might not have to explain what a conidiophore is, just link it to the conidia page, as well as maybe breaking down all those lists of properties).

Thisiseyes (talk) 21:53, 27 October 2016 (UTC)[reply]

Hey Lipei, I read your article and it is well-written because it is clear and concise. I also like how you divide the sections but I wonder if it is possible to add more section such as the fungus' origin instead of the introduction. I got a fungus which I cannot find too much information and not many references was my main struggle. Maybe this is also the reason why you do not have enough sources. However when I search Acrophialophora fusispora there are several cases reported. I think it will be really good to elaborate further on this. Especially they studied Acrophialophora fusispora in patient with cystic fibrosis or in immunodeficiency patient. Just search Acrophialophora fusispora on our library website and you will find many. I believe by describing more these clinical cases it will make your article more complete, give you more references and emphasize on the importance of your fungus in human health.

Second, there are some minor typo errors such as conidiophore, sometimes you wrote conidophore. Also there are few grammatical errors, for example the "s" after verb when it is third person singular. But these are minor details, I just realized these as I read through so you can just re-read and correct them. Overall this is a very good article, just elaborate more and it will be great. Xuji94 (talk) 18:15, 28 October 2016 (UTC)[reply]