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Welcome

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Welcome to Wikipedia and Wikiproject Medicine

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– the WikiProject Medicine team

Doc James (talk · contribs · email) 02:31, 23 June 2017 (UTC)[reply]

Feedback

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Hi. Your edits to the Anastrozole article were reverted, and I wanted to give you some sense of what the issues were. The feedback Doc James left you is valuable, and you should take a careful look at it, but I also wanted to give you some specific feedback.

When you changed the lead section of the article from this

Anastrozole, sold under the trade name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer. It has also been used to prevent breast cancer in those at high risk. It is taken by mouth.[1]

Common side effects include hot flashes, altered mood, joint pain, and nausea. Severe side effects include an increased risk of heart disease and osteoporosis. Use during pregnancy is known to harm the baby. Anastrozole is in the aromatase-inhibiting family of medications. It works by blocking the creation of estrogen.[1]

Anastrozole was patented in 1987 and approved for medical use in 1995.[4] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[5] Anastrozole is available as a generic medication.[1]

The wholesale cost in the developing world is about 1.92 to 30.60 USD a month.[6] In the United States the wholesale cost is about 3.81 USD per month.[7]

to this:

Anastrozole is a type of new generation endocrine therapy used to treat breast cancer. Specifically, it is an aromatase inhibitor pill for to stop estrogen production. It is used by patients with hormone receptor-positive breast cancer or those at high risk for developing cancer.

It was first approved by the FDA in 1995 and then again in 2000 as a first-line treatment[4] Common side effects include vasodilation, nausea, pain in the bone. Use during pregnancy is known to harm the baby.

you removed a lot of relevant information without providing a clear rationale for doing so.

The lead section is supposed to provide an overview of the major points in the article. If you make changes to the lead of an article, make sure that you are preserving the information that's already there. If you have a reason to removing content (e.g., if it's inaccurate) make sure that you explain your reasoning. And make sure that the lead continues to reflect the body of the article.

It's important to be consistent in your usage. You created a section entitled "In females", when the other sections were titled "In men" and "In children". To begin with, you have created overlapping categories (children can be female or male). "Females" isn't really an appropriate term for humans; it's more appropriate for non-human animals, and for that reason can be seen as demeaning. The adjective "female" is fine, but "woman" and "girl" are the noun forms for humans.

When writing about medical topics, especially treatment, it's extremely important that you make sure that you stick to WP:MEDRS. You need to be very careful with statements like "This opens the potential for Anastrozole to be used as an androgen replacement therapy in the future". For starters, you need to rely on recent review articles, not 13-year-old research studies. You also need to put things in proper context - speculation should be avoided. And speculation about "the future", from a source published more than a decade ago isn't about the future any more. It's a statement about the past that either came true (and shouldn't be speculated upon) or it didn't (and shouldn't be mentioned). Ian (Wiki Ed) (talk) 21:47, 26 June 2017 (UTC)[reply]