User:Yanping Nora Soong/M1

Recurring topics:

Medical biochem / general cell bio

• Cystic fibrosis transmembrane conductance regulator

Nucleic acid chemistry

Nuclear organization

• Nuclear pore

DNA repair

• Nucleotide excision repair
• Base excision repair
• Mismatch repair

Cell cycle and apoptosis

Cell cycle

• Restriction point
• G1 phase
• S phase
• G2 phase
• G2/M checkpoint

Mitosis

• Prophase: breakdown of the nuclear envelope is independent of microtubule assembly from the microtubule organizing center is separate from breakdown of the nuclear envelope which is complete at prometaphase
• Spindle checkpoint separates metaphase from anaphase
• Anaphase promoting complex

Tissue specialization / Histology

Staining patterns

• Hematoxylin and eosin
• Luxol fast blue stain
• Aldehyde fuchsin
• Trypan blue
• Periodic acid-Schiff stain

Epithelial

Cell junctions

• adherens junctions (zonula adherens) linked to actin filaments
• desmosomes (macula adherens) - linked to intermediate filaments
• gap junctions - small molecule intercellular transport
• tight junctions (zona occludens) - linked to actin filaments
• hemi-desmosomes - linked to intermediate filaments
• focal adhesions - linked to actin

Cell to extracellular matrix adhesion

• Integrin