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Synthetic Genomics

This page is about the company Synthetic Genomics. For the field related to synthetic biology, see Synthetic genomics.
Synthetic Genomics
FounderJ. Craig Venter
TypePrivate company
Location
Area served
Worldwide
ProductsInstruments
Reagents
Bioinformatics Tools
(Full list of products)
Services
(Full list of services)
Key people
Subsidiaries
  • SGI-DNA
  • Synthetic Genomics Vaccines (SGVI)
  • Genovia Bio
WebsiteSyntheticGenomics.com

Synthetic Genomics Inc. (SGI), is a private company that uses a pioneering foundation in the field of Synthetic genomics and cell biology to improve the sustainability of existing biological products and create new approaches to the development of vaccines, biofuels, pharmaceuticals and humanized organs. This foundation is built with core expertise in bioinformatics, metagenomics, automated liquid handling workflows and proprietary reagents that together form a bottom up approach to optimize the effectiveness of sustainable innovation in the growing application of synthetic biology to existing biologic products. Many of these products are developed in collaboration with other industry leaders including ExxonMobil, United Therapeutics, Novartis and ADM.

Synthetic Genomics was founded in part by J. Craig Venter. Venter's previous company, Celera Genomics, was a driving force in the race to sequence the Human Genome.[1] The firm takes its name from the phrase synthetic genomics which is a scientific discipline of synthetic biology related to the generation of organisms artificially using genetic material.[2][3]

History

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2006

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SGI was founded in the spring of 2005 by J. Craig Venter, Ph.D, Nobel Laureate Hamilton O. Smith, M.D., Juan Enriquez and David Kiernan, M.D., J.D.

2007

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SGI formed a collaboration with BP to develop and commercialize microbial-enhanced solutions to increase the conversion and recovery of subsurface hydrocarbons.[4]

2009

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In 2009, SGI received funding from ExxonMobil to produce biofuels on an industrial-scale using recombinant algae and other microorganisms. [5][6]

2010

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Life Technologies became an investor in Synthetic Genomics, Inc.[7]. In the same year, Synthetic Genomics also spun off a new subsidiary, Synthetic Genomics Vaccines Inc., to develop next generation vaccines[8]

2012

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The company purchased an 81 acre site in Southern California's Imperial valley to produce algae fuel for their collaboration with Exxon Mobil.[9]. They also signed a collaborative agreement with New England Biolabs to Launch Gibson Assembly™ Master Mix Product for Synthetic and Molecular Biology Applications[10]

2014

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In 2014 SGI expanded into the field of organ transplantation with a collaborative agreement with United Therapeutics valued at $50M[11] and brought in Oliver Fetzer, Ph.D., MBA as CEO[12]

2015

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In 2015 SGI launched its first instrument, the BioXp™ 3200 System.[13]

Products

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Commercialized products sold by Synthetic Genomics are sold through its subsidiary company SGI-DNA. Many of these products utilize the Gibson assembly method which was created by Dan Gibson (currently the Vice President of DNA Technology at SGI) in collaboration with the J. Craig Venter Institute in 2009.

Reagents

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  • The Gibson Assembly® HiFi 1 Step Kit
  • The Gibson Assembly® Ultra Kit
  • Gibson Assembly® Site-Directed Mutagenesis Kit
  • Gibson Assembly® Vectors

Instruments

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  • BioXp™ 3200 System

Software

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  • Archetype® software

References

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  1. ^ "About Synthetic Genomics". Synthetic Genomics' corporate website. Archived from the original on September 24, 2005. Retrieved November 26, 2005.
  2. ^ Whitehouse, David (July 4, 2005). "Venter revives synthetic bug talk". BBC.
  3. ^ Pennisi, E. (2010). "Genomics. Synthetic genome brings new life to bacterium". Science. 328 (5981): 958–959. doi:10.1126/science.328.5981.958. PMID 20488994.
  4. ^ Press Release
  5. ^ Juha-Pekka Tikka : Craig Venter Has Algae Biofuel in Synthetic Genomics’ Pipeline. Xconomy San Diego. 6/4/09.
  6. ^ "Scientist on plan to turn algae to fuel". NPR. July 15, 2009.
  7. ^ Press Release
  8. ^ Press Release
  9. ^ Synthetic Genomics Press release: May 24, 2012
  10. ^ Synthetic Genomics Press release: Feb 27, 2012
  11. ^ Synthetic Genomics Press release: Feb 27, 2012
  12. ^ Synthetic Genomics Press release: 10 27, 2014
  13. ^ Synthetic Genomics Press release: April 02, 2012
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Category:Biotechnology companies Category:Genetic engineering Category:Synthetic biology Category:Algae biomass producers

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