User:Ssmimx/sandbox

The CUUG tetraloop has the highest likelihood of conformational changes due to its structural flexibility. Out of the three tetraloops mentioned, this tetraloop is the most flexible since the second U is comparatively unrestricted.^[1] It is also very thermodynamically stable.^[2]

References

^ Hall, Kathleen B. (October 15, 2013). "RNA does the folding dance of twist, turn, stack". Proceedings of the National Academy of Sciences of the United States of America. 110 (42): 16706–7. Retrieved 22 May 2017.
^ Baumruk, V; Gouyette, C; Huynh-Dinh, T; Sun, JS; Ghomi, M (1 October 2001). "Comparison between CUUG and UUCG tetraloops: thermodynamic stability and structural features analyzed by UV absorption and vibrational spectroscopy". Nucleic Acids Research. 29 (19): 4089–96. PMID 11574692.

[1] Hall, Kathleen B. (October 15, 2013). "RNA does the folding dance of twist, turn, stack". Proceedings of the National Academy of Sciences of the United States of America. 110 (42): 16706–7. Retrieved 22 May 2017.

[2] Baumruk, V; Gouyette, C; Huynh-Dinh, T; Sun, JS; Ghomi, M (1 October 2001). "Comparison between CUUG and UUCG tetraloops: thermodynamic stability and structural features analyzed by UV absorption and vibrational spectroscopy". Nucleic Acids Research. 29 (19): 4089–96. PMID 11574692.

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