User:Robert M. Hunt

At the electron microscope...

I'm an 83-year-old retired grandfather with a broad range of interests.

For 31 years I was a scientist at the University of Pennsylvania School of Medicine. My research included light and electron microscopic examination of bone and cartilage.

I chronicled for the first time in living tissue:

1. the critical role of chondrocyte mitochondrial calcium during the primary calcification of epiphyseal plate and bone fracture cartilage, and,

2. in a bone fracture, the progressive transformation of endothelial cells and pericytes into mesenchymal cells and their subsequent development into chondrocytes.

Wikipedia articles initiated

History of my family

• William Bates (Quaker)
• Joshua Evans (Quaker minister)
• Alfred Hunt (steel magnate)
• Elisha Hunt (steamboat pioneer)
• Esther Hunt
• Henry Thomas Hunt
• John Hunt (Quaker minister)
• John Hunt Painter
• John Needles
• Joseph Pancoast

• Enterprise (1814)
• Monongahela and Ohio Steam Boat Company
• Mount Pleasant (Burlington County, New Jersey)

Other people and topics

• Abner Lawson Duncan
• John Fenwick (Quaker)
• Daniel French (inventor)
• Israel Gregg
• John Randolph Grymes
• John Hunt (Quaker exile)
• Robert Hunt (chaplain)
• Louis C. Hunter
• Alexander A. Maximow
• Barclay White
• Canterbury (ship)
• Comet (1813)

Significant contribution to a Wikipedia article initiated by another author

• Samuel Leeds Allen
• John Cadwalader (general)
• John S. Collins
• Edward Harris (ornithologist)
• Lou Henry Hoover
• Samuel K. Robbins
• Dave Robinson (American football)
• Robert H. Sayre
• Henry Miller Shreve
• Elizabeth Coleman White

• Battle of New Orleans
• Battle of Tientsin
• Bone healing
• Endochondral ossification
• Intramembranous ossification
• Mesenchymal stem cell
• Mitochondrion
• Moorestown High School
• Moorestown Township
• Osteoblast
• Osteoclast
• Paulsdale
• Secrest Octagon Barn
• Steamboats of the Mississippi

My images of my research work

• 
  Osteoclast
• 
  Osteoblasts
• 
  Basal lamina
• 
  Chondrocyte, stained for calcium, displaying its nucleus (N) and mitochondria (M)
• 
  Mesenchymal stem cell
• 
  Osteoprogenitor cells
• 
  Osteoblasts forming osteoid
• 
  Osteoblasts forming rudimentary bone tissue
• 
  Collagen fibers of woven bone
• 
  Hypertrophic zone of epiphyseal plate
• 
  Microvessel displaying an erythrocyte (E), endothelial cells and pericytes

My images

• 
  Alfred Hunt
• 
  Robert H. Sayre
• 
  Paulsdale
• 
  Plaque commemorating Petticoat Bridge skirmish
• 
  Mount Pleasant hill
• 
  Barzilla and Sarah Newbold house
• 
  Greenwich Fire Company
• 
  Greenwich Library
• 
  Wood House
• 
  Plaque commemorating Gen. John Cadwalader
• 
  Gen. John Cadwalader's grave
• 
  Man o' War statue at Kentucky Horse Park
• 
  Roberts Monument, Moorestown Twp., NJ

Selected publications

• Brighton, Carl T., Yoichi Sugioka, and Robert M. Hunt (1973). "Cytoplasmic structures of epiphyseal plate chondrocytes; quantitative evaluation using electron micrographs of rat costochondral junctions with specific reference to the fate of hypertrophic cells". Journal of Bone and Joint Surgery, 55-A: 771-784.

• Brighton, Carl T. and Robert M. Hunt (1974). "Mitochondrial calcium and its role in calcification". Clinical Orthopaedics and Related Research 100: 406-416.

• Brighton, Carl T. and Robert M. Hunt (1978). "The role of mitochondria in growth plate calcification as demonstrated in a rachitic model". Journal of Bone and Joint Surgery, 60-A: 630-639.

• Brighton, Carl T., Yoichi Sugioka, and Robert M. Hunt (1982). "Quantitative zonal analysis of cytoplasmic structures of growth-plate chondrocytes in vivo and in vitro". Journal of Bone and Joint Surgery, 64-A: 1336-1349.

• Brighton, Carl T., Toshihiro Kitajima, and Robert M. Hunt (1984). "Zonal analysis of cytoplasmic components of articular cartilage chondrocytes". Arthritis and Rheumatism, 27: 1290-1299.

• Brighton, Carl T. and Robert M. Hunt (1986). "Histochemical localization of calcium in the fracture callus with potassium pyroantimonate: possible role of chondrocyte mitochondrial calcium in callus calcification". Journal of Bone and Joint Surgery, 68-A (5): 703-715.

• Brighton, Carl T. and Robert M. Hunt (1986). "Ultrastructure of electrically induced osteogenesis in the rabbit medullary canal". Journal of Orthopaedic Research 4: 27-36.

• Brighton, Carl T. and Robert M. Hunt (1991). "Early histological and ultrastructural changes in medullary fracture callus". Journal of Bone and Joint Surgery, 73-A (6): 832-847.

• Brighton, Carl T. and Robert M. Hunt (1997). "Early histologic and ultrastructural changes in microvessels of periosteal callus". Journal of Orthopaedic Trauma, 11 (4): 244-253.