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Log file for Protein Box Bot

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Log page index: User:ProteinBoxBot/PBB_Log_Index

Protein Status Quick Log - Date: 14:31, 18 December 2007 (UTC)

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Proteins with a High Potential Match (1)

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ALPP

Redirected Proteins (24)

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PRDX5 STOM MAPRE1 ICOSLG KIF1B
HHEX LAMA4 H19 CHMP2B HTATSF1
IGLL1 DBNL EPS8 DUSP6 ITGB4BP
EPHB6 PPP1R15A EIF2C2 HMGN1 INSIG1
ARF3 ECT2 GJB3 ALDH3A1

Created (24)

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PRDX5 STOM MAPRE1 ICOSLG KIF1B
HHEX LAMA4 H19 CHMP2B HTATSF1
IGLL1 DBNL EPS8 DUSP6 ITGB4BP
EPHB6 PPP1R15A EIF2C2 HMGN1 INSIG1
ARF3 ECT2 GJB3 ALDH3A1

Manual Inspection (Page not found) (1)

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ALPP


Protein Status Grid - Date: 14:31, 18 December 2007 (UTC)

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HUGO Symbol Action Summary Target page(s) WP Symbol Search
PRDX5 Created Location: PRDX5; [1]
STOM Created Location: STOM; [2]
MAPRE1 Created Location: MAPRE1; [3]
ICOSLG Created Location: ICOSLG; [4]
KIF1B Created Location: KIF1B; [5]
HHEX Created Location: HHEX; [6]
LAMA4 Created Location: LAMA4; [7]
ALPP Manual Inspection (Page not found) Other Pages: Alkaline phosphatase (Protein Template); ALPP (No Data); ALP (Redirect -> Australian Labor Party); Alp (Unknown Data); PLAP (No Data); Plap (No Data); ALPG (No Data); Alpg (No Data); ALPPL (No Data); Alppl (No Data); GCAP (DisAmbig); Gcap (No Data); Australian Labor Party (Unknown Data); [8]
H19 Created Location: H19 (gene); [9]
CHMP2B Created Location: CHMP2B; [10]
HTATSF1 Created Location: HTATSF1; [11]
IGLL1 Created Location: IGLL1; [12]
DBNL Created Location: DBNL; [13]
EPS8 Created Location: EPS8; [14]
DUSP6 Created Location: DUSP6; [15]
ITGB4BP Created Location: EIF6; [16]
EPHB6 Created Location: EPHB6; [17]
PPP1R15A Created Location: PPP1R15A; [18]
EIF2C2 Created Location: EIF2C2; [19]
HMGN1 Created Location: HMGN1; [20]
INSIG1 Created Location: INSIG1; [21]
ARF3 Created Location: ARF3; [22]
ECT2 Created Location: ECT2; [23]
GJB3 Created Location: GJB3; [24]
ALDH3A1 Created Location: ALDH3A1; [25]

Vebose Log - Date: 14:31, 18 December 2007 (UTC)

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ALDH3A1

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  • INFO: Beginning work on ALDH3A1... {December 18, 2007 6:05:44 AM PST}
  • REDIRECT: Protein Redirected to: ALDH3A1 {December 18, 2007 6:06:17 AM PST}
  • CREATED: Created new protein page: ALDH3A1 {December 18, 2007 6:06:25 AM PST}

ALPP

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  • INFO: Beginning work on ALPP... {December 18, 2007 6:06:25 AM PST}
  • AMBIGUITY: Did not locate an acceptable page to update. {December 18, 2007 6:07:07 AM PST} 
 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image = PBB_Protein_ALPP_image.jpg
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1ew2.
 | PDB = {{PDB2|1ew2}}, {{PDB2|1zeb}}, {{PDB2|1zed}}, {{PDB2|1zef}}, {{PDB2|2glq}}
 | Name = Alkaline phosphatase, placental (Regan isozyme)
 | HGNCid = 439
 | Symbol = ALPP
 | AltSymbols =; ALP; PLAP; ALPG; ALPPL; GCAP
 | OMIM = 171800
 | ECnumber =  
 | Homologene = 55592
 | MGIid = 108009
 | GeneAtlas_image1 = PBB_GE_ALPP_204664_at_tn.png
 | GeneAtlas_image2 = PBB_GE_ALPP_211619_s_at_tn.png
 | GeneAtlas_image3 = PBB_GE_ALPP_210431_at_tn.png
 | Function = {{GNF_GO|id=GO:0000287 |text = magnesium ion binding}} {{GNF_GO|id=GO:0004035 |text = alkaline phosphatase activity}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}} {{GNF_GO|id=GO:0048503 |text = GPI anchor binding}} 
 | Component = {{GNF_GO|id=GO:0009986 |text = cell surface}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0008152 |text = metabolic process}} {{GNF_GO|id=GO:0016310 |text = phosphorylation}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 250
    | Hs_Ensembl = ENSG00000163283
    | Hs_RefseqProtein = NP_001623
    | Hs_RefseqmRNA = NM_001632
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 232951627
    | Hs_GenLoc_end = 232955832
    | Hs_Uniprot = P05187
    | Mm_EntrezGene = 11650
    | Mm_Ensembl = ENSMUSG00000026246
    | Mm_RefseqmRNA = NM_007433
    | Mm_RefseqProtein = NP_031459
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 88917861
    | Mm_GenLoc_end = 88921082
    | Mm_Uniprot = Q3ULC9
  }}
}}
'''Alkaline phosphatase, placental (Regan isozyme)''', also known as '''ALPP''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=250| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.<ref name="entrez">{{cite web | title = Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=250| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Nye KE, Riley GA, Pinching AJ |title=The defect seen in the phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4,5-tetrakisphosphate 5-phosphomonoesterase. |journal=Clin. Exp. Immunol. |volume=89 |issue= 1 |pages= 89-93 |year= 1992 |pmid= 1321014 |doi=  }}
*{{cite journal  | author=Lowe ME |title=Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein. |journal=J. Cell Biol. |volume=116 |issue= 3 |pages= 799-807 |year= 1992 |pmid= 1730777 |doi=  }}
*{{cite journal  | author=Micanovic R, Gerber LD, Berger J, ''et al.'' |title=Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 1 |pages= 157-61 |year= 1990 |pmid= 2153284 |doi=  }}
*{{cite journal  | author=Martin D, Spurr NK, Trowsdale J |title=RFLP of the human placental alkaline phosphatase gene (PLAP). |journal=Nucleic Acids Res. |volume=15 |issue= 21 |pages= 9104 |year= 1988 |pmid= 2891112 |doi=  }}
*{{cite journal  | author=Kam W, Clauser E, Kim YS, ''et al.'' |title=Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=82 |issue= 24 |pages= 8715-9 |year= 1986 |pmid= 3001717 |doi=  }}
*{{cite journal  | author=Knoll BJ, Rothblum KN, Longley M |title=Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution. |journal=J. Biol. Chem. |volume=263 |issue= 24 |pages= 12020-7 |year= 1988 |pmid= 3042787 |doi=  }}
*{{cite journal  | author=Micanovic R, Bailey CA, Brink L, ''et al.'' |title=Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 5 |pages= 1398-402 |year= 1988 |pmid= 3422741 |doi=  }}
*{{cite journal  | author=Knoll BJ, Rothblum KN, Longley M |title=Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases. |journal=Gene |volume=60 |issue= 2-3 |pages= 267-76 |year= 1988 |pmid= 3443302 |doi=  }}
*{{cite journal  | author=Ovitt CE, Strauss AW, Alpers DH, ''et al.'' |title=Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 11 |pages= 3781-5 |year= 1986 |pmid= 3459156 |doi=  }}
*{{cite journal  | author=Henthorn PS, Knoll BJ, Raducha M, ''et al.'' |title=Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 15 |pages= 5597-601 |year= 1986 |pmid= 3461452 |doi=  }}
*{{cite journal  | author=Millán JL |title=Molecular cloning and sequence analysis of human placental alkaline phosphatase. |journal=J. Biol. Chem. |volume=261 |issue= 7 |pages= 3112-5 |year= 1986 |pmid= 3512548 |doi=  }}
*{{cite journal  | author=Ezra E, Blacher R, Udenfriend S |title=Purification and partial sequencing of human placental alkaline phosphatase. |journal=Biochem. Biophys. Res. Commun. |volume=116 |issue= 3 |pages= 1076-83 |year= 1984 |pmid= 6651840 |doi=  }}
*{{cite journal  | author=Le Du MH, Stigbrand T, Taussig MJ, ''et al.'' |title=Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity. |journal=J. Biol. Chem. |volume=276 |issue= 12 |pages= 9158-65 |year= 2001 |pmid= 11124260 |doi= 10.1074/jbc.M009250200 }}
*{{cite journal  | author=Spurway TD, Dalley JA, High S, Bulleid NJ |title=Early events in glycosylphosphatidylinositol anchor addition. substrate proteins associate with the transamidase subunit gpi8p. |journal=J. Biol. Chem. |volume=276 |issue= 19 |pages= 15975-82 |year= 2001 |pmid= 11278620 |doi= 10.1074/jbc.M010128200 }}
*{{cite journal  | author=Rump A, Kasper G, Hayes C, ''et al.'' |title=Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1. |journal=Genomics |volume=73 |issue= 1 |pages= 50-5 |year= 2001 |pmid= 11352565 |doi= 10.1006/geno.2000.6504 }}
*{{cite journal  | author=Wennberg C, Kozlenkov A, Di Mauro S, ''et al.'' |title=Structure, genomic DNA typing, and kinetic characterization of the D allozyme of placental alkaline phosphatase (PLAP/ALPP). |journal=Hum. Mutat. |volume=19 |issue= 3 |pages= 258-67 |year= 2002 |pmid= 11857742 |doi= 10.1002/humu.10052 }}
*{{cite journal  | author=Kozlenkov A, Manes T, Hoylaerts MF, Millán JL |title=Function assignment to conserved residues in mammalian alkaline phosphatases. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22992-9 |year= 2002 |pmid= 11937510 |doi= 10.1074/jbc.M202298200 }}
*{{cite journal  | author=Tang J, Li W |title=[Methodological study on the assay of glycosylphosphatidylinositol-specific phospholipase D activity in serum] |journal=Hunan Yi Ke Da Xue Xue Bao |volume=24 |issue= 2 |pages= 119-22 |year= 2002 |pmid= 11938765 |doi=  }}
*{{cite journal  | author=Lehto MT, Sharom FJ |title=Proximity of the protein moiety of a GPI-anchored protein to the membrane surface: a FRET study. |journal=Biochemistry |volume=41 |issue= 26 |pages= 8368-76 |year= 2002 |pmid= 12081485 |doi=  }}
*{{cite journal  | author=Le Du MH, Millan JL |title=Structural evidence of functional divergence in human alkaline phosphatases. |journal=J. Biol. Chem. |volume=277 |issue= 51 |pages= 49808-14 |year= 2003 |pmid= 12372831 |doi= 10.1074/jbc.M207394200 }}
}}
{{refend}}

{{protein-stub}}

ARF3

[edit]
  • INFO: Beginning work on ARF3... {December 18, 2007 6:07:07 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein ARF3 image.jpg {December 18, 2007 6:08:40 AM PST}
  • REDIRECT: Protein Redirected to: ARF3 {December 18, 2007 6:08:47 AM PST}
  • CREATED: Created new protein page: ARF3 {December 18, 2007 6:08:55 AM PST}

CHMP2B

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  • INFO: Beginning work on CHMP2B... {December 18, 2007 6:28:55 AM PST}
  • REDIRECT: Protein Redirected to: CHMP2B {December 18, 2007 6:30:04 AM PST}
  • CREATED: Created new protein page: CHMP2B {December 18, 2007 6:30:13 AM PST}

DBNL

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  • INFO: Beginning work on DBNL... {December 18, 2007 6:31:47 AM PST}
  • UPLOAD: Added new Image to wiki: {December 18, 2007 6:32:10 AM PST}
  • REDIRECT: Protein Redirected to: DBNL {December 18, 2007 6:32:17 AM PST}
  • CREATED: Created new protein page: DBNL {December 18, 2007 6:32:25 AM PST}

DUSP6

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  • INFO: Beginning work on DUSP6... {December 18, 2007 6:08:55 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein DUSP6 image.jpg {December 18, 2007 6:10:24 AM PST}
  • REDIRECT: Protein Redirected to: DUSP6 {December 18, 2007 6:10:32 AM PST}
  • CREATED: Created new protein page: DUSP6 {December 18, 2007 6:10:40 AM PST}

ECT2

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  • INFO: Beginning work on ECT2... {December 18, 2007 6:10:40 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein ECT2 image.jpg {December 18, 2007 6:11:58 AM PST}
  • REDIRECT: Protein Redirected to: ECT2 {December 18, 2007 6:12:06 AM PST}
  • CREATED: Created new protein page: ECT2 {December 18, 2007 6:12:14 AM PST}

EIF2C2

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  • INFO: Beginning work on EIF2C2... {December 18, 2007 6:30:13 AM PST}
  • REDIRECT: Protein Redirected to: EIF2C2 {December 18, 2007 6:30:28 AM PST}
  • CREATED: Created new protein page: EIF2C2 {December 18, 2007 6:30:36 AM PST}

EPHB6

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  • INFO: Beginning work on EPHB6... {December 18, 2007 6:13:15 AM PST}
  • REDIRECT: Protein Redirected to: EPHB6 {December 18, 2007 6:13:47 AM PST}
  • CREATED: Created new protein page: EPHB6 {December 18, 2007 6:13:55 AM PST}

EPS8

[edit]
  • INFO: Beginning work on EPS8... {December 18, 2007 6:13:55 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein EPS8 image.jpg {December 18, 2007 6:14:40 AM PST}
  • REDIRECT: Protein Redirected to: EPS8 {December 18, 2007 6:14:48 AM PST}
  • CREATED: Created new protein page: EPS8 {December 18, 2007 6:14:56 AM PST}

GJB3

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  • INFO: Beginning work on GJB3... {December 18, 2007 6:14:56 AM PST}
  • REDIRECT: Protein Redirected to: GJB3 {December 18, 2007 6:16:09 AM PST}
  • CREATED: Created new protein page: GJB3 {December 18, 2007 6:16:18 AM PST}

H19

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  • INFO: Beginning work on H19... {December 18, 2007 6:32:25 AM PST}
  • REDIRECT: Protein Redirected to: H19 (gene) {December 18, 2007 6:33:01 AM PST}
  • CREATED: Created new protein page: H19 (gene) {December 18, 2007 6:33:10 AM PST}

HHEX

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  • INFO: Beginning work on HHEX... {December 18, 2007 6:16:18 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein HHEX image.jpg {December 18, 2007 6:18:29 AM PST}
  • REDIRECT: Protein Redirected to: HHEX {December 18, 2007 6:18:37 AM PST}
  • CREATED: Created new protein page: HHEX {December 18, 2007 6:18:44 AM PST}

HMGN1

[edit]
  • INFO: Beginning work on HMGN1... {December 18, 2007 6:18:44 AM PST}
  • REDIRECT: Protein Redirected to: HMGN1 {December 18, 2007 6:18:58 AM PST}
  • CREATED: Created new protein page: HMGN1 {December 18, 2007 6:19:06 AM PST}

HTATSF1

[edit]
  • INFO: Beginning work on HTATSF1... {December 18, 2007 6:30:36 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein HTATSF1 image.jpg {December 18, 2007 6:31:32 AM PST}
  • REDIRECT: Protein Redirected to: HTATSF1 {December 18, 2007 6:31:39 AM PST}
  • CREATED: Created new protein page: HTATSF1 {December 18, 2007 6:31:47 AM PST}

ICOSLG

[edit]
  • INFO: Beginning work on ICOSLG... {December 18, 2007 6:26:21 AM PST}
  • REDIRECT: Protein Redirected to: ICOSLG {December 18, 2007 6:26:52 AM PST}
  • CREATED: Created new protein page: ICOSLG {December 18, 2007 6:27:00 AM PST}

IGLL1

[edit]
  • INFO: Beginning work on IGLL1... {December 18, 2007 6:19:06 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein IGLL1 image.jpg {December 18, 2007 6:20:14 AM PST}
  • REDIRECT: Protein Redirected to: IGLL1 {December 18, 2007 6:20:21 AM PST}
  • CREATED: Created new protein page: IGLL1 {December 18, 2007 6:20:29 AM PST}

INSIG1

[edit]
  • INFO: Beginning work on INSIG1... {December 18, 2007 6:20:29 AM PST}
  • REDIRECT: Protein Redirected to: INSIG1 {December 18, 2007 6:21:42 AM PST}
  • CREATED: Created new protein page: INSIG1 {December 18, 2007 6:21:50 AM PST}

ITGB4BP

[edit]
  • INFO: Beginning work on ITGB4BP... {December 18, 2007 6:21:50 AM PST}
  • REDIRECT: Protein Redirected to: EIF6 {December 18, 2007 6:22:46 AM PST}
  • CREATED: Created new protein page: EIF6 {December 18, 2007 6:22:54 AM PST}

KIF1B

[edit]
  • INFO: Beginning work on KIF1B... {December 18, 2007 6:25:53 AM PST}
  • REDIRECT: Protein Redirected to: KIF1B {December 18, 2007 6:26:13 AM PST}
  • CREATED: Created new protein page: KIF1B {December 18, 2007 6:26:21 AM PST}

LAMA4

[edit]
  • INFO: Beginning work on LAMA4... {December 18, 2007 6:22:54 AM PST}
  • REDIRECT: Protein Redirected to: LAMA4 {December 18, 2007 6:24:28 AM PST}
  • CREATED: Created new protein page: LAMA4 {December 18, 2007 6:24:36 AM PST}

MAPRE1

[edit]
  • INFO: Beginning work on MAPRE1... {December 18, 2007 6:24:36 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein MAPRE1 image.jpg {December 18, 2007 6:25:36 AM PST}
  • REDIRECT: Protein Redirected to: MAPRE1 {December 18, 2007 6:25:43 AM PST}
  • CREATED: Created new protein page: MAPRE1 {December 18, 2007 6:25:53 AM PST}

PPP1R15A

[edit]
  • INFO: Beginning work on PPP1R15A... {December 18, 2007 6:27:00 AM PST}
  • REDIRECT: Protein Redirected to: PPP1R15A {December 18, 2007 6:27:48 AM PST}
  • CREATED: Created new protein page: PPP1R15A {December 18, 2007 6:27:57 AM PST}

PRDX5

[edit]
  • INFO: Beginning work on PRDX5... {December 18, 2007 6:27:57 AM PST}
  • UPLOAD: Added new Image to wiki: File:PBB Protein PRDX5 image.jpg {December 18, 2007 6:28:40 AM PST}
  • REDIRECT: Protein Redirected to: PRDX5 {December 18, 2007 6:28:47 AM PST}
  • CREATED: Created new protein page: PRDX5 {December 18, 2007 6:28:55 AM PST}

STOM

[edit]
  • INFO: Beginning work on STOM... {December 18, 2007 6:12:14 AM PST}
  • REDIRECT: Protein Redirected to: STOM {December 18, 2007 6:13:05 AM PST}
  • CREATED: Created new protein page: STOM {December 18, 2007 6:13:15 AM PST}

end log.

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