Log page index: User:ProteinBoxBot/PBB_Log_Index
Protein Status Quick Log - Date: 05:15, 26 November 2007 (UTC)
[edit]Proteins without matches (23)
[edit]Proteins with a High Potential Match (1)
[edit]Redirected Proteins (1)
[edit]Manual Inspection (Page not found) (8)
[edit]
Protein Status Grid - Date: 05:15, 26 November 2007 (UTC)
[edit]Vebose Log - Date: 05:15, 26 November 2007 (UTC)
[edit]- INFO: Beginning work on CALCRL... {November 25, 2007 9:04:32 PM PST}
- REDIRECT: Protein Redirected to: CALCRL {November 25, 2007 9:04:56 PM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {November 25, 2007 9:04:59 PM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {November 25, 2007 9:04:59 PM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {November 25, 2007 9:04:59 PM PST}
- UPDATED: Updated protein page: CALCRL {November 25, 2007 9:05:05 PM PST}
- INFO: Beginning work on CCR9... {November 25, 2007 9:09:06 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:09:54 PM PST}
- CREATED: Created new protein page: CCR9 {November 25, 2007 9:10:04 PM PST}
- INFO: Beginning work on CELSR1... {November 25, 2007 9:00:11 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:01:56 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
| HGNCid = 1850
| Symbol = CELSR1
| AltSymbols =; ME2; CDHF9; DKFZp434P0729; FMI2; HFMI2
| OMIM = 604523
| ECnumber =
| Homologene = 7665
| MGIid = 1100883
| GeneAtlas_image1 = PBB_GE_CELSR1_41660_at_tn.png
| GeneAtlas_image2 = PBB_GE_CELSR1_204539_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_CELSR1_217262_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0046983 |text = protein dimerization activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0001843 |text = neural tube closure}} {{GNF_GO|id=GO:0007156 |text = homophilic cell adhesion}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007417 |text = central nervous system development}} {{GNF_GO|id=GO:0007626 |text = locomotory behavior}} {{GNF_GO|id=GO:0042249 |text = establishment of polarity of embryonic epithelium}} {{GNF_GO|id=GO:0042472 |text = inner ear morphogenesis}} {{GNF_GO|id=GO:0045176 |text = apical protein localization}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 9620
| Hs_Ensembl = ENSG00000075275
| Hs_RefseqProtein = NP_055061
| Hs_RefseqmRNA = NM_014246
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 22
| Hs_GenLoc_start = 45135395
| Hs_GenLoc_end = 45311731
| Hs_Uniprot = Q9NYQ6
| Mm_EntrezGene = 12614
| Mm_Ensembl = ENSMUSG00000016028
| Mm_RefseqmRNA = NM_009886
| Mm_RefseqProtein = NP_034016
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 15
| Mm_GenLoc_start = 85728699
| Mm_GenLoc_end = 85861536
| Mm_Uniprot = Q571L9
}}
}}
'''Cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)''', also known as '''CELSR1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9620| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis.<ref name="entrez">{{cite web | title = Entrez Gene: CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9620| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Nollet F, Kools P, van Roy F |title=Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. |journal=J. Mol. Biol. |volume=299 |issue= 3 |pages= 551-72 |year= 2000 |pmid= 10835267 |doi= 10.1006/jmbi.2000.3777 }}
*{{cite journal | author=Hadjantonakis AK, Sheward WJ, Harmar AJ, ''et al.'' |title=Celsr1, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter. |journal=Genomics |volume=45 |issue= 1 |pages= 97-104 |year= 1997 |pmid= 9339365 |doi= 10.1006/geno.1997.4892 }}
*{{cite journal | author=Wu Q, Maniatis T |title=A striking organization of a large family of human neural cadherin-like cell adhesion genes. |journal=Cell |volume=97 |issue= 6 |pages= 779-90 |year= 1999 |pmid= 10380929 |doi= }}
*{{cite journal | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
*{{cite journal | author=Wu Q, Maniatis T |title=Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3124-9 |year= 2000 |pmid= 10716726 |doi= 10.1073/pnas.060027397 }}
*{{cite journal | author=Ghosh A |title=Dentritic growth: don't go says flamingo. |journal=Neuron |volume=28 |issue= 1 |pages= 3-4 |year= 2000 |pmid= 11086974 |doi= }}
*{{cite journal | author=Gross J, Grimm O, Ortega G, ''et al.'' |title=Mutational analysis of the neuronal cadherin gene CELSR1 and exclusion as a candidate for catatonic schizophrenia in a large family. |journal=Psychiatr. Genet. |volume=11 |issue= 4 |pages= 197-200 |year= 2002 |pmid= 11807409 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Georgieva L, Nikolov I, Poriazova N, ''et al.'' |title=Genetic variation in the seven-pass transmembrane cadherin CELSR1: lack of association with schizophrenia. |journal=Psychiatr. Genet. |volume=13 |issue= 2 |pages= 103-6 |year= 2004 |pmid= 12782967 |doi= 10.1097/01.ypg.0000057486.14812.03 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Carroll JS, Liu XS, Brodsky AS, ''et al.'' |title=Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. |journal=Cell |volume=122 |issue= 1 |pages= 33-43 |year= 2005 |pmid= 16009131 |doi= 10.1016/j.cell.2005.05.008 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on CXCR6... {November 25, 2007 9:05:53 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:06:58 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Chemokine (C-X-C motif) receptor 6
| HGNCid = 16647
| Symbol = CXCR6
| AltSymbols =; BONZO; CD186; STRL33; TYMSTR
| OMIM = 605163
| ECnumber =
| Homologene = 38197
| MGIid = 1934582
| GeneAtlas_image1 = PBB_GE_CXCR6_206974_at_tn.png
| GeneAtlas_image2 = PBB_GE_CXCR6_211469_s_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0015026 |text = coreceptor activity}} {{GNF_GO|id=GO:0016493 |text = C-C chemokine receptor activity}} {{GNF_GO|id=GO:0016494 |text = C-X-C chemokine receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0019079 |text = viral genome replication}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 10663
| Hs_Ensembl = ENSG00000172215
| Hs_RefseqProtein = NP_006555
| Hs_RefseqmRNA = NM_006564
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 3
| Hs_GenLoc_start = 45957429
| Hs_GenLoc_end = 45964833
| Hs_Uniprot = O00574
| Mm_EntrezGene = 80901
| Mm_Ensembl = ENSMUSG00000048521
| Mm_RefseqmRNA = NM_030712
| Mm_RefseqProtein = NP_109637
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 9
| Mm_GenLoc_start = 123655197
| Mm_GenLoc_end = 123660458
| Mm_Uniprot =
}}
}}
'''Chemokine (C-X-C motif) receptor 6''', also known as '''CXCR6''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CXCR6 chemokine (C-X-C motif) receptor 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10663| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Ruibal-Ares BH, Belmonte L, Baré PC, ''et al.'' |title=HIV-1 infection and chemokine receptor modulation. |journal=Curr. HIV Res. |volume=2 |issue= 1 |pages= 39-50 |year= 2004 |pmid= 15053339 |doi= }}
*{{cite journal | author=Liao F, Alkhatib G, Peden KW, ''et al.'' |title=STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. |journal=J. Exp. Med. |volume=185 |issue= 11 |pages= 2015-23 |year= 1997 |pmid= 9166430 |doi= }}
*{{cite journal | author=Deng HK, Unutmaz D, KewalRamani VN, Littman DR |title=Expression cloning of new receptors used by simian and human immunodeficiency viruses. |journal=Nature |volume=388 |issue= 6639 |pages= 296-300 |year= 1997 |pmid= 9230441 |doi= 10.1038/40894 }}
*{{cite journal | author=Loetscher M, Amara A, Oberlin E, ''et al.'' |title=TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function. |journal=Curr. Biol. |volume=7 |issue= 9 |pages= 652-60 |year= 1998 |pmid= 9285716 |doi= }}
*{{cite journal | author=Hoffman TL, Stephens EB, Narayan O, Doms RW |title=HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11360-5 |year= 1998 |pmid= 9736741 |doi= }}
*{{cite journal | author=Schramm B, Penn ML, Speck RF, ''et al.'' |title=Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease. |journal=J. Virol. |volume=74 |issue= 1 |pages= 184-92 |year= 2000 |pmid= 10590105 |doi= }}
*{{cite journal | author=Tscherning-Casper C, Vödrös D, Menu E, ''et al.'' |title=Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European Network for In Utero Transmission of HIV-1. |journal=J. Acquir. Immune Defic. Syndr. |volume=24 |issue= 1 |pages= 1-9 |year= 2000 |pmid= 10877489 |doi= }}
*{{cite journal | author=Ignatius R, Wei Y, Beaulieu S, ''et al.'' |title=The immunodeficiency virus coreceptor, Bonzo/STRL33/TYMSTR, is expressed by macaque and human skin- and blood-derived dendritic cells. |journal=AIDS Res. Hum. Retroviruses |volume=16 |issue= 11 |pages= 1055-9 |year= 2000 |pmid= 10933620 |doi= 10.1089/08892220050075318 }}
*{{cite journal | author=Unutmaz D, Xiang W, Sunshine MJ, ''et al.'' |title=The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. |journal=J. Immunol. |volume=165 |issue= 6 |pages= 3284-92 |year= 2000 |pmid= 10975845 |doi= }}
*{{cite journal | author=Matloubian M, David A, Engel S, ''et al.'' |title=A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. |journal=Nat. Immunol. |volume=1 |issue= 4 |pages= 298-304 |year= 2001 |pmid= 11017100 |doi= 10.1038/79738 }}
*{{cite journal | author=Wilbanks A, Zondlo SC, Murphy K, ''et al.'' |title=Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. |journal=J. Immunol. |volume=166 |issue= 8 |pages= 5145-54 |year= 2001 |pmid= 11290797 |doi= }}
*{{cite journal | author=Lee B, Leslie G, Soilleux E, ''et al.'' |title=cis Expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor. |journal=J. Virol. |volume=75 |issue= 24 |pages= 12028-38 |year= 2001 |pmid= 11711593 |doi= 10.1128/JVI.75.24.12028-12038.2001 }}
*{{cite journal | author=Calabresi PA, Yun SH, Allie R, Whartenby KA |title=Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNgamma-producing effector cells. |journal=J. Neuroimmunol. |volume=127 |issue= 1-2 |pages= 96-105 |year= 2002 |pmid= 12044980 |doi= }}
*{{cite journal | author=Kim CH, Johnston B, Butcher EC |title=Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity. |journal=Blood |volume=100 |issue= 1 |pages= 11-6 |year= 2002 |pmid= 12070001 |doi= 10.1182/blood-2001-12-0196 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Duggal P, An P, Beaty TH, ''et al.'' |title=Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans. |journal=Genes Immun. |volume=4 |issue= 4 |pages= 245-50 |year= 2004 |pmid= 12761559 |doi= 10.1038/sj.gene.6363950 }}
*{{cite journal | author=Koprak S, Matheravidathu S, Springer M, ''et al.'' |title=Down-regulation of cell surface CXCR6 expression during T cell activation is predominantly mediated by calcineurin. |journal=Cell. Immunol. |volume=223 |issue= 1 |pages= 1-12 |year= 2003 |pmid= 12914753 |doi= }}
*{{cite journal | author=Shimaoka T, Nakayama T, Fukumoto N, ''et al.'' |title=Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells. |journal=J. Leukoc. Biol. |volume=75 |issue= 2 |pages= 267-74 |year= 2004 |pmid= 14634054 |doi= 10.1189/jlb.1003465 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on CYSLTR1... {November 25, 2007 9:08:20 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:08:56 PM PST}
- CREATED: Created new protein page: CYSLTR1 {November 25, 2007 9:09:06 PM PST}
- INFO: Beginning work on EDG5... {November 25, 2007 8:55:05 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 8:55:55 PM PST}
- CREATED: Created new protein page: EDG5 {November 25, 2007 8:56:05 PM PST}
- INFO: Beginning work on FZD10... {November 25, 2007 9:12:57 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:13:38 PM PST}
- CREATED: Created new protein page: FZD10 {November 25, 2007 9:13:45 PM PST}
- INFO: Beginning work on GABBR2... {November 25, 2007 8:56:44 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 8:58:31 PM PST}
- CREATED: Created new protein page: GABBR2 {November 25, 2007 9:00:11 PM PST}
- INFO: Beginning work on GLP2R... {November 25, 2007 8:56:05 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 8:56:44 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Glucagon-like peptide 2 receptor
| HGNCid = 4325
| Symbol = GLP2R
| AltSymbols =;
| OMIM = 603659
| ECnumber =
| Homologene = 3132
| MGIid = 2136733
| GeneAtlas_image1 = PBB_GE_GLP2R_221312_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007188 |text = G-protein signaling, coupled to cAMP nucleotide second messenger}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 9340
| Hs_Ensembl = ENSG00000065325
| Hs_RefseqProtein = NP_004237
| Hs_RefseqmRNA = NM_004246
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 17
| Hs_GenLoc_start = 9670106
| Hs_GenLoc_end = 9733747
| Hs_Uniprot = O95838
| Mm_EntrezGene = 93896
| Mm_Ensembl =
| Mm_RefseqmRNA = XM_991784
| Mm_RefseqProtein = XP_996878
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Glucagon-like peptide 2 receptor''', also known as '''GLP2R''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GLP2R glucagon-like peptide 2 receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9340| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).<ref name="entrez">{{cite web | title = Entrez Gene: GLP2R glucagon-like peptide 2 receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9340| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Burrin DG, Petersen Y, Stoll B, Sangild P |title=Glucagon-like peptide 2: a nutrient-responsive gut growth factor. |journal=J. Nutr. |volume=131 |issue= 3 |pages= 709-12 |year= 2001 |pmid= 11238747 |doi= }}
*{{cite journal | author=Munroe DG, Gupta AK, Kooshesh F, ''et al.'' |title=Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 4 |pages= 1569-73 |year= 1999 |pmid= 9990065 |doi= }}
*{{cite journal | author=Yusta B, Huang L, Munroe D, ''et al.'' |title=Enteroendocrine localization of GLP-2 receptor expression in humans and rodents. |journal=Gastroenterology |volume=119 |issue= 3 |pages= 744-55 |year= 2000 |pmid= 10982769 |doi= }}
*{{cite journal | author=Thulesen J, Knudsen LB, Hartmann B, ''et al.'' |title=The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist. |journal=Regul. Pept. |volume=103 |issue= 1 |pages= 9-15 |year= 2002 |pmid= 11738243 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Koehler JA, Yusta B, Drucker DJ |title=The HeLa cell glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways. |journal=Mol. Endocrinol. |volume=19 |issue= 2 |pages= 459-73 |year= 2005 |pmid= 15471943 |doi= 10.1210/me.2004-0196 }}
*{{cite journal | author=Ørskov C, Hartmann B, Poulsen SS, ''et al.'' |title=GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors. |journal=Regul. Pept. |volume=124 |issue= 1-3 |pages= 105-12 |year= 2005 |pmid= 15544847 |doi= 10.1016/j.regpep.2004.07.009 }}
*{{cite journal | author=Mahon MJ, Shimada M |title=Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors. |journal=FEBS Lett. |volume=579 |issue= 3 |pages= 803-7 |year= 2005 |pmid= 15670850 |doi= 10.1016/j.febslet.2004.12.056 }}
*{{cite journal | author=Estall JL, Koehler JA, Yusta B, Drucker DJ |title=The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation. |journal=J. Biol. Chem. |volume=280 |issue= 23 |pages= 22124-34 |year= 2005 |pmid= 15817468 |doi= 10.1074/jbc.M500078200 }}
*{{cite journal | author=Guan X, Karpen HE, Stephens J, ''et al.'' |title=GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. |journal=Gastroenterology |volume=130 |issue= 1 |pages= 150-64 |year= 2006 |pmid= 16401478 |doi= 10.1053/j.gastro.2005.11.005 }}
*{{cite journal | author=Sams A, Hastrup S, Andersen M, Thim L |title=Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines. |journal=Eur. J. Pharmacol. |volume=532 |issue= 1-2 |pages= 18-23 |year= 2006 |pmid= 16448646 |doi= 10.1016/j.ejphar.2005.12.001 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on GPR176... {November 25, 2007 9:13:45 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:14:29 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = G protein-coupled receptor 176
| HGNCid = 32370
| Symbol = GPR176
| AltSymbols =; GPR; Gm1012
| OMIM =
| ECnumber =
| Homologene = 5226
| MGIid = 2685858
| GeneAtlas_image1 = PBB_GE_GPR176_206673_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007268 |text = synaptic transmission}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 11245
| Hs_Ensembl = ENSG00000166073
| Hs_RefseqProtein = NP_009154
| Hs_RefseqmRNA = NM_007223
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 15
| Hs_GenLoc_start = 37880223
| Hs_GenLoc_end = 38000385
| Hs_Uniprot = Q14439
| Mm_EntrezGene = 381413
| Mm_Ensembl = ENSMUSG00000040133
| Mm_RefseqmRNA = NM_201367
| Mm_RefseqProtein = NP_958755
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 117968551
| Mm_GenLoc_end = 118064752
| Mm_Uniprot = Q80WT4
}}
}}
'''G protein-coupled receptor 176''', also known as '''GPR176''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR176 G protein-coupled receptor 176| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11245| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Hata S, Emi Y, Iyanagi T, Osumi T |title=cDNA cloning of a putative G protein-coupled receptor from brain. |journal=Biochim. Biophys. Acta |volume=1261 |issue= 1 |pages= 121-5 |year= 1995 |pmid= 7893747 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on GPR45... {November 25, 2007 9:14:29 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:15:10 PM PST}
- CREATED: Created new protein page: GPR45 {November 25, 2007 9:15:18 PM PST}
- INFO: Beginning work on GPR52... {November 25, 2007 8:54:25 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 8:54:58 PM PST}
- CREATED: Created new protein page: GPR52 {November 25, 2007 8:55:05 PM PST}
- INFO: Beginning work on GPR55... {November 25, 2007 8:53:58 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 8:54:17 PM PST}
- CREATED: Created new protein page: GPR55 {November 25, 2007 8:54:25 PM PST}
- INFO: Beginning work on GPR56... {November 25, 2007 8:52:55 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 8:53:58 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = G protein-coupled receptor 56
| HGNCid = 4512
| Symbol = GPR56
| AltSymbols =; BFPP; DKFZp781L1398; TM7LN4; TM7XN1
| OMIM = 604110
| ECnumber =
| Homologene = 4156
| MGIid = 1340051
| GeneAtlas_image1 = PBB_GE_GPR56_212070_at_tn.png
| GeneAtlas_image2 = PBB_GE_GPR56_206582_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}} {{GNF_GO|id=GO:0007420 |text = brain development}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 9289
| Hs_Ensembl = ENSG00000205336
| Hs_RefseqProtein = NP_005673
| Hs_RefseqmRNA = NM_005682
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 16
| Hs_GenLoc_start = 56241701
| Hs_GenLoc_end = 56256445
| Hs_Uniprot = Q9Y653
| Mm_EntrezGene = 14766
| Mm_Ensembl = ENSMUSG00000031785
| Mm_RefseqmRNA = NM_018882
| Mm_RefseqProtein = NP_061370
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 8
| Mm_GenLoc_start = 97866238
| Mm_GenLoc_end = 97903324
| Mm_Uniprot = Q8K209
}}
}}
'''G protein-coupled receptor 56''', also known as '''GPR56''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR56 G protein-coupled receptor 56| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9289| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Xu L, Hynes RO |title=GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. |journal=Cell Cycle |volume=6 |issue= 2 |pages= 160-5 |year= 2007 |pmid= 17314516 |doi= }}
*{{cite journal | author=Liu M, Parker RM, Darby K, ''et al.'' |title=GPR56, a novel secretin-like human G-protein-coupled receptor gene. |journal=Genomics |volume=55 |issue= 3 |pages= 296-305 |year= 1999 |pmid= 10049584 |doi= 10.1006/geno.1998.5644 }}
*{{cite journal | author=Zendman AJ, Cornelissen IM, Weidle UH, ''et al.'' |title=TM7XN1, a novel human EGF-TM7-like cDNA, detected with mRNA differential display using human melanoma cell lines with different metastatic potential. |journal=FEBS Lett. |volume=446 |issue= 2-3 |pages= 292-8 |year= 1999 |pmid= 10100861 |doi= }}
*{{cite journal | author=Piao X, Basel-Vanagaite L, Straussberg R, ''et al.'' |title=An autosomal recessive form of bilateral frontoparietal polymicrogyria maps to chromosome 16q12.2-21. |journal=Am. J. Hum. Genet. |volume=70 |issue= 4 |pages= 1028-33 |year= 2002 |pmid= 11845408 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal | author=Little KD, Hemler ME, Stipp CS |title=Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association. |journal=Mol. Biol. Cell |volume=15 |issue= 5 |pages= 2375-87 |year= 2005 |pmid= 15004227 |doi= 10.1091/mbc.E03-12-0886 }}
*{{cite journal | author=Piao X, Hill RS, Bodell A, ''et al.'' |title=G protein-coupled receptor-dependent development of human frontal cortex. |journal=Science |volume=303 |issue= 5666 |pages= 2033-6 |year= 2004 |pmid= 15044805 |doi= 10.1126/science.1092780 }}
*{{cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819-24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Shashidhar S, Lorente G, Nagavarapu U, ''et al.'' |title=GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion. |journal=Oncogene |volume=24 |issue= 10 |pages= 1673-82 |year= 2005 |pmid= 15674329 |doi= 10.1038/sj.onc.1208395 }}
*{{cite journal | author=Sud N, Sharma R, Ray R, ''et al.'' |title=Differential expression of G-protein coupled receptor 56 in human esophageal squamous cell carcinoma. |journal=Cancer Lett. |volume=233 |issue= 2 |pages= 265-70 |year= 2006 |pmid= 15916848 |doi= 10.1016/j.canlet.2005.03.018 }}
*{{cite journal | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal | author=Xu L, Begum S, Hearn JD, Hynes RO |title=GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 24 |pages= 9023-8 |year= 2006 |pmid= 16757564 |doi= 10.1073/pnas.0602681103 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on GPR64... {November 25, 2007 9:02:46 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:03:36 PM PST}
- CREATED: Created new protein page: GPR64 {November 25, 2007 9:03:43 PM PST}
- INFO: Beginning work on GPR75... {November 25, 2007 9:12:06 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:12:49 PM PST}
- CREATED: Created new protein page: GPR75 {November 25, 2007 9:12:57 PM PST}
- INFO: Beginning work on GPR83... {November 25, 2007 9:11:43 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:12:06 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = G protein-coupled receptor 83
| HGNCid = 4523
| Symbol = GPR83
| AltSymbols =; GIR; GPR72
| OMIM = 605569
| ECnumber =
| Homologene = 7732
| MGIid = 95712
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004983 |text = neuropeptide Y receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 10888
| Hs_Ensembl = ENSG00000123901
| Hs_RefseqProtein = NP_057624
| Hs_RefseqmRNA = NM_016540
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 93750131
| Hs_GenLoc_end = 93774066
| Hs_Uniprot = Q9NYM4
| Mm_EntrezGene = 14608
| Mm_Ensembl = ENSMUSG00000031932
| Mm_RefseqmRNA = NM_010287
| Mm_RefseqProtein = NP_034417
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 9
| Mm_GenLoc_start = 14610647
| Mm_GenLoc_end = 14619892
| Mm_Uniprot = Q542Q9
}}
}}
'''G protein-coupled receptor 83''', also known as '''GPR83''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR83 G protein-coupled receptor 83| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10888| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parker R, Liu M, Eyre HJ, ''et al.'' |title=Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6. |journal=Biochim. Biophys. Acta |volume=1491 |issue= 1-3 |pages= 369-75 |year= 2000 |pmid= 10760605 |doi= }}
*{{cite journal | author=Nagase T, Kikuno R, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 2 |pages= 143-50 |year= 2000 |pmid= 10819331 |doi= }}
*{{cite journal | author=De Moerlooze L, Williamson J, Liners F, ''et al.'' |title=Cloning and chromosomal mapping of the mouse and human genes encoding the orphan glucocorticoid-induced receptor (GPR83). |journal=Cytogenet. Cell Genet. |volume=90 |issue= 1-2 |pages= 146-50 |year= 2000 |pmid= 11060465 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Hansen W, Loser K, Westendorf AM, ''et al.'' |title=G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo. |journal=J. Immunol. |volume=177 |issue= 1 |pages= 209-15 |year= 2006 |pmid= 16785516 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on NMUR1... {November 25, 2007 9:05:05 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:05:53 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Neuromedin U receptor 1
| HGNCid = 4518
| Symbol = NMUR1
| AltSymbols =; (FM-3); FM-3; FM3; GPC-R; GPR66; NMU1R
| OMIM = 604153
| ECnumber =
| Homologene = 68501
| MGIid = 1341898
| GeneAtlas_image1 = PBB_GE_NMUR1_221383_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0001607 |text = neuromedin U receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006816 |text = calcium ion transport}} {{GNF_GO|id=GO:0006821 |text = chloride transport}} {{GNF_GO|id=GO:0006939 |text = smooth muscle contraction}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007202 |text = phospholipase C activation}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0019226 |text = transmission of nerve impulse}} {{GNF_GO|id=GO:0019722 |text = calcium-mediated signaling}} {{GNF_GO|id=GO:0045045 |text = secretory pathway}} {{GNF_GO|id=GO:0048016 |text = inositol phosphate-mediated signaling}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 10316
| Hs_Ensembl = ENSG00000171596
| Hs_RefseqProtein = NP_006047
| Hs_RefseqmRNA = NM_006056
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 2
| Hs_GenLoc_start = 232096116
| Hs_GenLoc_end = 232103452
| Hs_Uniprot = Q9HB89
| Mm_EntrezGene = 14767
| Mm_Ensembl = ENSMUSG00000026237
| Mm_RefseqmRNA = NM_010341
| Mm_RefseqProtein = NP_034471
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 1
| Mm_GenLoc_start = 88217496
| Mm_GenLoc_end = 88219312
| Mm_Uniprot = Q0VB23
}}
}}
'''Neuromedin U receptor 1''', also known as '''NMUR1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NMUR1 neuromedin U receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10316| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Tan CP, McKee KK, Liu Q, ''et al.'' |title=Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors. |journal=Genomics |volume=52 |issue= 2 |pages= 223-9 |year= 1998 |pmid= 9782091 |doi= 10.1006/geno.1998.5441 }}
*{{cite journal | author=Fujii R, Hosoya M, Fukusumi S, ''et al.'' |title=Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. |journal=J. Biol. Chem. |volume=275 |issue= 28 |pages= 21068-74 |year= 2000 |pmid= 10783389 |doi= 10.1074/jbc.M001546200 }}
*{{cite journal | author=Szekeres PG, Muir AI, Spinage LD, ''et al.'' |title=Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20247-50 |year= 2000 |pmid= 10811630 |doi= 10.1074/jbc.C000244200 }}
*{{cite journal | author=Raddatz R, Wilson AE, Artymyshyn R, ''et al.'' |title=Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32452-9 |year= 2000 |pmid= 10899166 |doi= 10.1074/jbc.M004613200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Mori K, Miyazato M, Ida T, ''et al.'' |title=Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. |journal=EMBO J. |volume=24 |issue= 2 |pages= 325-35 |year= 2005 |pmid= 15635449 |doi= 10.1038/sj.emboj.7600526 }}
*{{cite journal | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on NPFFR2... {November 25, 2007 9:10:04 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:10:28 PM PST}
- CREATED: Created new protein page: NPFFR2 {November 25, 2007 9:10:36 PM PST}
- INFO: Beginning work on OR5I1... {November 25, 2007 9:07:42 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:08:20 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 5, subfamily I, member 1
| HGNCid = 8347
| Symbol = OR5I1
| AltSymbols =; OLF1; HSOlf1
| OMIM = 608496
| ECnumber =
| Homologene = 4835
| MGIid = 1313139
| GeneAtlas_image1 = PBB_GE_OR5I1_208521_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 10798
| Hs_Ensembl = ENSG00000167825
| Hs_RefseqProtein = NP_006628
| Hs_RefseqmRNA = NM_006637
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 55459508
| Hs_GenLoc_end = 55460452
| Hs_Uniprot = Q13606
| Mm_EntrezGene = 258640
| Mm_Ensembl = ENSMUSG00000068816
| Mm_RefseqmRNA = NM_146646
| Mm_RefseqProtein = NP_666857
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 87583375
| Mm_GenLoc_end = 87584325
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 5, subfamily I, member 1''', also known as '''OR5I1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10798| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10798| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Issel-Tarver L, Rine J |title=The evolution of mammalian olfactory receptor genes. |journal=Genetics |volume=145 |issue= 1 |pages= 185-95 |year= 1997 |pmid= 9017400 |doi= }}
*{{cite journal | author=Buettner JA, Glusman G, Ben-Arie N, ''et al.'' |title=Organization and evolution of olfactory receptor genes on human chromosome 11. |journal=Genomics |volume=53 |issue= 1 |pages= 56-68 |year= 1998 |pmid= 9787077 |doi= 10.1006/geno.1998.5422 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on P2RY14... {November 25, 2007 9:01:56 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:02:38 PM PST}
- CREATED: Created new protein page: P2RY14 {November 25, 2007 9:02:46 PM PST}
- INFO: Beginning work on P2RY5... {November 25, 2007 9:03:43 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:04:24 PM PST}
- CREATED: Created new protein page: P2RY5 {November 25, 2007 9:04:32 PM PST}
- INFO: Beginning work on PROKR1... {November 25, 2007 9:10:36 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:11:35 PM PST}
- CREATED: Created new protein page: PROKR1 {November 25, 2007 9:11:43 PM PST}
- INFO: Beginning work on RRH... {November 25, 2007 9:06:58 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:07:32 PM PST}
- CREATED: Created new protein page: RRH {November 25, 2007 9:07:42 PM PST}
- INFO: Beginning work on TAAR3... {November 25, 2007 8:52:28 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 8:52:48 PM PST}
- CREATED: Created new protein page: TAAR3 {November 25, 2007 8:52:55 PM PST}
end log.
