User:Pammy1998/OLES2129/draft

3 April 2019

Seminar Leader: Dr Daniel Dixon

Article Title:

Physiological active compounds (https://en.wikipedia.org/wiki/Physiological_active_compounds)

Associated WikiProjects:

My Wikipedia page is from requested articles, correlated to disciplines of Chemistry, Medicinal chemistry, physiology and photochemistry.

The following Wikipedia pages are related to my chosen topic:

-      https://en.wikipedia.org/wiki/Natural_product

-      https://en.wikipedia.org/wiki/Phytochemical

-      https://en.wikipedia.org/wiki/Pharmacology

Description:

Physiology is the study of how organism’s organs activitates and functions to respond and adapt to the environment.

Physiological active compounds are any substances that cause an effect on plants, animals or humans function/activities. Pharmacologically and physiologically, all organism possesses some specific receptors that have specific ligand. Physiologically active compounds are the ligands to these receptors and by binding them they work as an agonist to activate the receptor. The response to this activation would change how the cell functions depending on the selectivity, specifity and potency of the compound.

Most of the chemicals either natural or synthesised produce a response on the body if their mechanism of action becomes clear.

Titles of Sections:

-      Definition and mechanism of action

-      Examples:

1)   Humic substances

2)   Siderophores

3)   Plant growth regulators

4)   Allelopathics

5)   Vitamins

6)   Antibiotics

7)   Extracellular soil enzymes

8)   Microbial and soil fauna stimulants

9)   Natural insecticides or hericides

Sources and Annotations: the followings are not the full list of my resources as they are plenty more, however all articles are from reliable websites like PubMed and SciencDirect so the validity will be same but the number of articles/ chapter books will be more in final version.

In this article, the Humic substances been widely investigated and gives a broad understanding on what Humic substances are and what they uses are in a simple language that is understandable for general public and not only experts.

ScienceDirect is one of the most comprehensive websites that has numerous number of articles/books/chapters, and is highly reliable in any scientific fields.

These resources are varying in published date however the validity of them is highly regarded in universities and other scientific researches.

Pubmed is part of NCBI, one of the most important/valid/reliable resources in the world. It is connected to American national library of medicine and institution of health and is highly regarded as one of the best resources use in science in not only in tertiary education but any research. The article chosen from this website is to show the molecular properties of Humic substances and their mechanism of action in a more advanced level. I used this article to show in molecular level how the Humic substance are activate in body aspect and how they affect the physiology of effected organ.

JBC (Journal of Biological Chemistry) is another great resource in science that is highly regarded in tertiary education. In this article, the properties and mechanism of action of Siderophores been explored. It gives a broad understanding of how these chemicals make their way through the body, why they are activating in physiological environment and how they affect the body. This article is also demonstrated the chemistry of these compounds that can be used for supporting documents.

This article is also from ScienceDirect that already stated how reliable is as the resources in scientific researches. This article looked at the physiologically active compounds from another point of view that could potentially have its on specific section on my Wikipedia page as the marine science and active substances is a broad part of science itself, however I decided to only put that as interesting fact in my “definition and mechanism of action” section.

Alexander Wf, Kotkis Aj, the properties of the physiologically active substances in the body resulting from the administration of acetyl beta methyl choline chloride by the iontrophoresis. ASPET, 1936 December, 58(4), p-p 439-453.

The Journal of Pharmacology and experimental therapeutics (JPET) is again one of the greatest resources in pharmacological fields. In this article the properties and mechanism of action of Physiologically active compounds been investigated with specific chemicals. The experiment is carried out with high scientific standards and the results are all very useful in my introduction section on my Wikipedia page.

Shenkin A. Basics in clinical nutrition: physiological function and defiency states of vitamins, June 2008, 3, p-p 275-280. DIO https://doi.org/10.1016/j.eclnm.2008.06.008

Clinical Nutrition ESPEN had uploaded this article from ELSEVIER that is associated with the Science Direct forum. In this article, the mechanism of action of proteins been investigated and not only how they become activated in the body but also how they play an important role in normal healthy body. The vitamins section of my Wikipedia page will have the most information on it as the vitamins are the best known to the public and therefore they are very important example to under stance what a physiologically active compound does in the body.

Siyang J, Jianwi Li, Ji C, Gangsheng W, Melanie A, Mayes, Judjo E etl, Soil extracellural enzyme ativir=ties, soil carbon and nitrogen storage under nitrogen fertilization: A meta analysis. ScienceDirect, ELSEVIER, 2016 October, 1001. P-p 32-43. DIO: https://doi.org/10.1016/j.soilbio.2016.07.003

This article is also from science direct. I used this article for Extracellular soil enzymes as I found it interesting how something unusual effect the body in physiological aspect.