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User:Mr. Ibrahem/Keratosis pilaris1

From Wikipedia, the free encyclopedia
Keratosis pilaris
Other namesFollicular keratosis, lichen pilaris, chicken skin[1]
Keratosis pilaris as seen on the calf
SpecialtyDermatology
SymptomsPainless red bumpy skin[2]
Usual onsetEarly childhood[2]
DurationLong term[2]
Risk factorsObesity, atopic dermatitis, ichthyosis vulgaris, pregnancy, diabetes[1]
Diagnostic methodBased on symptoms and examination[2]
Differential diagnosisAcne, folliculitis, atopic dermatitis, milia, scurvy[2]
TreatmentMoisturizers, creams that include lactic acid or salicylic acid, phototherapy[1][2]
PrognosisNot serious[2]
FrequencyCommon[2]

Keratosis pilaris (KP) is a condition that results in red bumpy skin.[2] There is generally no pain or itchiness.[2] The most commonly involves areas are the back of the upper arms, thighs, and buttocks.[2] Less frequently the face, chest, or forearms may be involved.[2] Often it gets better during the summer and worse during the winter.[2] It may result in psychological distress.[2]

KP has an autosomal dominant genetic inheritance.[2] It is associated with obesity, atopic dermatitis, ichthyosis vulgaris, pregnancy, diabetes, and rarely cancer.[1] It may also be associated with a number of genetic syndromes.[1] The underlying mechanism is not completely understood.[2] Proposals include that it is an abnormality in the process of depositing the keratin in hair follicles, abnormalities in the hair shaft, or both.[1] Diagnosis is usually based on the skin's appearance; however, dermoscopy may be useful in unclear cases.[1][2]

There is no cure; though, the condition often improves with time.[2] Treatments may improve the appearance.[2] This may include applying moisturizers and medications such as lactic acid, salicylic acid, urea, or retinoids to the skin.[1] Fractional carbon dioxide lasers and Nd:YAG laser therapies may also be tried.[1] Onset is often in later childhood with up to 80% affected, with it still present in about 40% of adults.[2] Though others report rates of 0.8% to 34% of the population.[1]

References

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  1. ^ a b c d e f g h i j Wang, JF; Orlow, SJ (July 2018). "Keratosis Pilaris and its Subtypes: Associations, New Molecular and Pharmacologic Etiologies, and Therapeutic Options". American Journal of Clinical Dermatology. 19 (5): 733–757. doi:10.1007/s40257-018-0368-3. PMID 30043128.
  2. ^ a b c d e f g h i j k l m n o p q r s t Pennycook, KB; McCready, TA (January 2020). "Keratosis Pilaris". PMID 31536314. {{cite journal}}: Cite journal requires |journal= (help)