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The organochlorine pentachlorophenol (PCP, C₆Cl₅OH) is a wood preservative biocide.

Structure

PCP is a polychlorinated aromatic:

Degradation

PCP is degraded by some bacteria, including Sphingobium chlorophenolicum^[1].

PCP → TCHQ → DCHQ → 2,4-dichloro-3-hydroxy-cis,cis-muconic semialdehyde ^[2]

References

^ Copley, S.D (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends in Biochemical Sciences. 25: 261–265. doi:10.1016/S0968-0004(00)01562-0.
^ Imamura, Kiyomichi; Yoshitane, Hikari; Hattori, Kazuki; Yamaguchi, Mitsuo; Yoshida, Kento; Okubo, Takenori; Naguro, Isao; Ichijo, Hidenori; Fukada, Yoshitaka (3 April 2018). "ASK family kinases mediate cellular stress and redox signaling to circadian clock". Proceedings of the National Academy of Sciences. 115 (14): 3646–3651. doi:10.1073/pnas.1719298115.

External links

US EPA pentachlorophenol in drinking water

[Copley2000-1] Copley, S.D (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends in Biochemical Sciences. 25: 261–265. doi:10.1016/S0968-0004(00)01562-0.

[2] Imamura, Kiyomichi; Yoshitane, Hikari; Hattori, Kazuki; Yamaguchi, Mitsuo; Yoshida, Kento; Okubo, Takenori; Naguro, Isao; Ichijo, Hidenori; Fukada, Yoshitaka (3 April 2018). "ASK family kinases mediate cellular stress and redox signaling to circadian clock". Proceedings of the National Academy of Sciences. 115 (14): 3646–3651. doi:10.1073/pnas.1719298115.

[1]

[2]