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Proposal for Hemostasis Page

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Our proposal for the Hemostasis page is an outline that will help us further create quality contributions to an already established Wiki page. Through this process we will take comments and suggestions from other users to better our writing. We will also be conducting our own research in order to make sure we are giving accurate and informative information.

I. Definition

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Cam Apt will do this section

  • What is hemostasis? [1] [2] [3]
  • Who does it affect?
  • Where was the name originated from ( why is it called what it is)?
  • Who discovered hemostasis?

I. Why Does this Occur

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  • Here we will talk about why hemostasis occurs and what causes the cascade of events [4]
  • What types of chemical signals are given off to start hemostasis [5]
  • What would happen if hemostasis didn't occur?

III. Mechanism of Hemostasis

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Marissa Ray and Cam Apt will work on this section.

  • Here we will give a detailed description of how hemostasis actually occurs. [6]
  • We will express the pathways and mechanisms that must take place
  • We will talk about other components of the blood that are involved in this process
  • We will talk about the three major steps involved in hemostasis in great detail in order to further explain the importance of this process
  • The Three major steps include: vasoconstriction, temporary blockage of a break by a platelet plug, and blood coagulation
  • Express the importance of further mechanisms that need to be performed in order to maintain what hemostasis has done.

IV. Types of Hemostasis

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Cam Apt and Marissa Ray will work on this section

  • Hemostasis can be achieved in many different ways when it comes to the body not doing it naturally (or needs help) especially during surgery or medical treatment
  • The main type of hemostasis that we will cover include:[7]
   Chemical/topical
   Electrocoagulation
   Direct pressure or pressure dressing
   Sutures and ties
   Physical agents (gelatin sponge).
  • We will give an explanation of these as well as explain when they would be used.
  • How much does natural hemostasis aid in these various types?
  • How important is it to be able to stimulate hemostasis?

V. Hemostasis in Emergency Medicine

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Jory Gotham Will work on this section.

  • Here we will talk about the importance of hemostasis in emergency situations [8]
  • How do health care professionals handle problems that arise from lack/to much hemostasis occurring? [9]
  • How do these problems affect the care for the patient?

VI. Primary Hemostasis

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Jory Gotham Will work on this section.

  • Here we will define Primary hemostasis and its role in the process of blood clotting.[10]
  • What causes this to occur?
  • When does this occur in the body?
  • Why does this occur? What types of chemical signals allow this process to start? [11]

VII. Secondary Hemostasis

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Jory Gotham Will work on this section

  • Here we will define Secondary Hemostasis and its main job in the process of blood clotting. [12]
  • What causes it to occur in the body?
  • When does this occur in the body?
  • Why does this occur in the body?
  • What would happen if we did not have this step?

VIII.Problems

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Marissa Ray will work on this section.

  • Here we will talk about certain types of problems that could occur if hemostasis did not work the way it does.
  • What types of impact would it have on the body? [13]
  • What diseases are associated with a malfunction of this process, and what causes them to occur? [14]
  • Does any specific diseases/condition provoke or change hemostasis? If so, what and why? [15]
  • Is there any way to treat the condition?

References

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. Marissa Ray, Jory Gotham , and Cam Apt will work on this section.

  1. ^ Jagadeeswaran, P. "A Hemophilia Model in Zebrafish: Analysis of Hemostasis." Blood Cells, Molecules, and Diseases 23.1 (1997): 52-57.
  2. ^ Boon, G. D. "An Overview of Hemostasis." Toxicologic Pathology 21.2 (1993): 170-79.
  3. ^ Wies, C. H. "The History of Hemostasis." Yale Journal of Biology and Medicine 2 (1929): 167-68.
  4. ^ Nemerson Y. Tissue factor and Hemostasis. Journal of Thrombosis & Haemostasis. 1988 Jan;71(1):1–8.
  5. ^ Marieb, Elaine Nicpon, and Katja Hoehn. Human Anatomy & Physiology. 8th ed. San Francisco: Benjamin Cummings, 2010. 649-50.
  6. ^ Jagadeeswaran, Pudur, and Yuan C. Liu. "Developmental Expression of Thrombin in Zebrafish Embryos: A Novel Model to Study Hemostasis." Blood Cells, Molecules, and Diseases 23.2 (1997): 147-56.
  7. ^ Kulkarni, Roshni. "Alternative and Topical Approaches to Treating the Massicely Bleeding Patient." Ed. Craig M. Kessler. Advances in Hematology 2.7 (2004): 428-31. Clinical Advances. Current Development in the Management of Hematologic Disorders.
  8. ^ Sterz, Fritz, and Konrad Weiss. Thrombosis and Hemostasis in Emergency Medicine. New York: Thieme, 1996.
  9. ^ Levy, Jerrold H., Richard P. Dutton, J. Claude Hemphill, Aryeh Shander, David Cooper, Michael J. Paidas, Craig M. Kessler, John B. Holcomb, and Jeffrey H. Lawson. "Multidisciplinary Approach to the Challenge of Hemostasis." Anesthesia & Analgesia 110.2 (2010): 354-64.
  10. ^ Clemetson, Kenneth J. "Platelets And Primary Haemostasis." Thrombosis Research 129.3 (2012): 220-224.
  11. ^ McMichael, Maureen. "Primary Hemostasis." Journal of Veterinary Emergency and Critical Care 15.1 (2005): 1-8.
  12. ^ Müüller, Felicitas, and Thomas Rennéé. "Platelet Polyphosphates: The Nexus Of Primary And Secondary Hemostasis." Scandinavian Journal Of Clinical & Laboratory Investigation 71.2 (2011): 82-86.
  13. ^ Tocantins, Leandro M., William O. Reid, Melvin J. Silver, and Louis A. Kazal. "Current Problems In Hemostasis." Annals of the New York Academy of Sciences 115.2 Computers in (1964): 21-30.
  14. ^ SRIVASTAVA, et al. "Tests Of Global Haemostasis And Their Applications In Bleeding Disorders." Haemophilia 16.(2010): 85-92.
  15. ^ Robert J. Porte, et al. "Hemostasis And Thrombosis In Patients With Liver Disease: The Ups And Downs." Journal Of Hepatology 53.2 (2010): 362-371.