User:M2bioinfo-Orsay/sandbox
| SQ1002 RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of SQ1002 | |
| Identifiers | |
| Symbol | SQ1002 |
| Rfam | XXXX |
| Other data | |
| RNA type | Gene; sRNA |
| Domain(s) | Bacteria |
| PDB structures | PDBe |
SQ1002 is a 191nt small RNA identified in Clostridioides difficile 630 by RNA deep sequencing and confirmed by Northern Blot and RT-PCR [1]. Extremities were confirmed by 5’ and 3’-RACE.
This RNA is found in several C. difficile strains in syntenic positions between a putative acyltransferase gene and a Ferrous iron transport gene. No homologues were found outside C. difficile, although a putative paralogue was found in C. difficile 630, located between a Tryptophanyl-tRNA synthetase gene and a pseudogene.
Due to lack of sequence variation, the proposed secondary structure is not supported by any covariation and should be considered speculative.
References
[edit]- ^ Soutourina OA, Monot M, Boudry P, Saujet L, Pichon C, Sismeiro O; et al. (2013). "Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile". PLOS Genet. 9 (5): e1003493. doi:10.1371/journal.pgen.1003493. PMC 3649979. PMID 23675309.
{{cite journal}}: CS1 maint: multiple names: authors list (link)