User:Kbelardo/sandbox

Changes to VDAC1 page includes the following

• add murine PDB (3EMN)
• Add more visualizations of the pore from lateral views along with channel dimensions
• Information on structure determination. i.e. discovered by 3 separate labs via x-ray crystallography (with citations)
• Information debating the conformational mechanism of closure. i.e. N-terminus no longer shown to close the pore in mVDAC1 (with citations)
• In the functions paragraph, I am going to add background on the outer mitochondrial membrane and the fact that it was once thought to be leaky but is now shown to be filled with VDAC1 channels that mediate flux of metabolites
• Information on the voltage gating of the channel (under low voltage, it allows very little conductance whereas high voltage allows more conductance of ions)
• More detailed information on how the MPTP complex forms along with visual representations