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User:Irisissis/L19 Ribosomal Protein Leader

From Wikipedia, the free encyclopedia
Ribosomal protein L19 leader
Predicted secondary structure and sequence conservation of L19_leader
Identifiers
SymbolL19_leader
RfamRF00556
Other data
RNA typeCis-reg; leader
Domain(s)Bacteria
SOSO:0000233
PDB structuresPDBe

L19 Ribosomal protein leaders are part of the ribosome biogenesis. They were used as an autoregulatory mechanism to control the concentration of ribosomal proteins L19. This family is a putative ribosomal protein leader autoregulatory structure[1] found in B. subtilis and other low-GC Gram-positive bacteria. It is located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L19 (rplS). More examples were predicted in Flavobacteria[2] or Firmicutes[3] with bioinformatic approaches. The structures of all these predicted L19 ribosomal leaders are similar.

References

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  1. ^ Zengel JM, Lindahl L (1994). "Diverse mechanisms for regulating ribosomal protein synthesis in Escherichia coli". Progress in Nucleic Acid Research and Molecular Biology. Progress in Nucleic Acid Research and Molecular Biology. 47: 331–370. doi:10.1016/S0079-6603(08)60256-1. ISBN 978-0-12-540047-3. PMID 7517053.
  2. ^ Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130). doi:10.1186/s12866-020-01823-6.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  3. ^ Yao, Z; Barrick, J; Weinberg, Z; Neph, S; Breaker, R; Tompa, M; Ruzzo, WL (2007). "A computational pipeline for high-throughput discovery of cis-regulatory noncoding RNA in prokaryotes". PLoS Comput Biol. 3 (7). doi:10.1371/journal.pcbi.0030126.{{cite journal}}: CS1 maint: unflagged free DOI (link)
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Category:Ribosomal protein leader