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Transgender Women Hormone Use (Estradiol):

Hormones like ethinyestradiol are not used just by women. They are also used by males transitioning into females, commonly referred to as, transgender women. Women produce more estrogen than men, thus transitioning males use estrogen (what form? cite this) in order to gain female characteristics. (Cite what kind of effects it causes). Breast development, more adipose tissue on the body, softening of facial features. However this doesn't change the male genitialia that they were born with, this just changes more of the physical appearance.

Medical uses[edit source]

There are many uses for ethinylestradiol (EE). It is most commonly used as contraception in combined oral contraceptives (COC), also known as birth control, to prevent pregnancy after sex. EE in its birth control formulation is not only used to prevent pregnancy, but can also be used to treat amenorrhea, dysmenorrhea, and acne. The amount of EE in COCs has reduced over the years.^[1]

EE is also used as hormone replacement therapy (HRT) for menopausal women. The main reason for using HRT in menopausal women is to relieve common vasomotor symptoms such as hot flashes, night sweats, and flushing. Studies have found that estrogen replacement helps improve these symptoms when compared to a placebo.^[2] Other common menopause symptoms such as vaginal dryness (which can cause pain during sexual intercourse), vaginal itching, and depressed mood, can benefit from HRT. For women with an intact uterus, it is crucial to not give ethinylestradiol or any estrogen alone due to the possible increased risk of endometrial cancer.^[3] Thus, EE is usually given in combination with a progestin.

Moreover, EE can also be used to treat female hypogonadism, prevent osteoporosis, and be used as palliative care for prostate cancer (in men).

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^ "Do You Need to Take Ethinyl Estradiol (Synthetic Estrogen)?". Verywell. Retrieved 2017-11-01.
^ Hamoda, Panay, Arya, Savvas, H, N, R (2016). "The British Menopause Society & Women's Health Concern 2016 recommendations on hormone replacement therapy in menopausal women". Post Reproductive Health. 22 (4): 165–183. doi:10.1177/2053369116680501. S2CID 79429244 – via SAGE.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ "The Women's Health Initiative (WHI) Clinical Trial of Estrogen plus Progestin in Postmenopausal Women" (PDF). Food and Drug Administration. Retrieved November 6th 2017. {{cite web}}: Check date values in: |access-date= (help)

[1] "Do You Need to Take Ethinyl Estradiol (Synthetic Estrogen)?". Verywell. Retrieved 2017-11-01.

[2] Hamoda, Panay, Arya, Savvas, H, N, R (2016). "The British Menopause Society & Women's Health Concern 2016 recommendations on hormone replacement therapy in menopausal women". Post Reproductive Health. 22 (4): 165–183. doi:10.1177/2053369116680501. S2CID 79429244 – via SAGE.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[3] "The Women's Health Initiative (WHI) Clinical Trial of Estrogen plus Progestin in Postmenopausal Women" (PDF). Food and Drug Administration. Retrieved November 6th 2017. {{cite web}}: Check date values in: |access-date= (help)

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