User:Hannahberhow/sandbox

Beebe Lake

Beebe Lake was named for an early settler. This lake is 323 acres in size. It is approximately 27 feet deep at its deepest point.

Goldy Gopher statue

Due to the contributions from students, faculty, family, alumni, and friends, the University of Minnesota’s Student Union was able to fund the creation of an all bronze statue of Goldy the Gopher. This was a controversial issue for some in the University community because of the rising costs of tuition and the University’s concurrent appeals to the state legislature for a tuition freeze. The goal of the statue, located in the front of Coffman Memorial Union, was to promote school spirit and start new traditions. The University of Minnesota Administration hopes the iconic symbol will help students interact with the spirit and new traditions involving Goldy the Gopher. The statue is 6 feet, 3 inches (1.9 m) tall and made of bronze granite. Next to the statue is a solid granite "M" that is 63 inches in width, 24 Inches in depth, and 48 inches in height (160 x 61 x 122 cm). It was sculpted by Nicholas Legeros, who is a Minnesota graduate from the fine arts academy. He has sculpted many pieces for the Twin Cities Metro area. The total cost of the statue was $95,000 dollars.

Albertville Premium Outlets

Albertville Premium Outlets has one anchor store located on their property, Ashley Home Furniture Studio. Also, Albertville Premium Outlets is home to a few dining options, which include TCBY Yogurt, Burger King, Five Guys, Starbucks, and Subway.

Beluga Whales

Belugas are gregarious and form groups of up to 10 animals on average, although during the summer, they can gather in the hundreds or even thousands in estuaries and shallow coastal areas. They are slow swimmers, but can dive to 700 m (2,300 ft) below the surface. They are opportunistic feeders and their diets vary according to their locations and the season. The majority of belugas live in the Arctic Ocean and the seas and coasts around North America, Russia and Greenland; their worldwide population is thought to number around 150,000. They are migratory and the majority of groups spend the winter around the Arctic ice cap; when the sea ice melts in summer, they move to warmer river estuaries and coastal areas. Some populations are sedentary and do not migrate over great distances during the year.

Quakers in Ireland

Quakers in Ireland, The Religious Society of Friends (Quakers) have a long history in Ireland their first recorded Meeting for Worship in Ireland was in 1654 at the home of William Edmundson in Lurgan, Co. Armagh.

Uncharacterized Protein C11orf42

Chromosome 11 Open Reading Frame 42 is a highly conserved gene in eukaryotes. The mRNA sequence is 1,149 basepairs in length and contains 3 exons. It encodes a protein of unknown function that is 333 amino acids in length and weighs 34.6 kDA. The protein is expressed broadly in testes and skin. The C11orf42 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat and 136 organisms have orthologs of this gene. The nucleotide contains the conserved protein domain PFAM15668.Its top transcription factor binding sites are Gfi-1, HEN1, Lmo2, MyoD, and NF-1. C11orf42 is also known to interact with sorting nexin-5 (SNX5) which is a protein involved in mediating retrograde transport of cargo proteins from endosomes to the trans-golgi network.

Polychrysia Distribution

Polychrysia can be found in Russia, Canada, USA, Europe, and East Asia.

Nomada marshamella Flight Period

Apparently both univoltine and bivoltine, depending on the host Andrena which is attacked. The univoltine form is apparently associated with A. carantonica and A. nigroaenea (Kirby) and flies in the spring and early summer from early April to late June. The host of the bivoltine form is not known for certain but it may attack both broods of A. trimmerana (Kirby) and late nesting A. carantonica and nigroaenea, both the latter species having a single, greatly extended flight period. This form flies from April to June and again from late June to the beginning of September. The Nomada is certainly more numerous in the spring and early summer than later in the year.[5]

History

The Sgt. William H. Carney House is a historic house at 128 Mill Street in New Bedford, Massachusetts. The house was built in 1856, and is a 2-1/2 story wood frame structure with Greek Revival styling. It has a three-bay front facade, with the entrance in the left bay, sheltered by a hip-roofed bracketed hood. It is notable as the home of William Harvey Carney, an enlistee in the African-American 54th Massachusetts Volunteer Infantry. Carney distinguished himself at the Battle of Fort Wagner, actions for which he was belatedly awarded the Medal of Honor.

Landscape

The Crow River, North Fork flows southeast from Lake Koronis for about 125 miles until it joins the Mississippi River at Dayton. The roughly 40 mile stretch from upstream of Rockford to the Mississippi is considered to be the the best for canoeing. Upstream from Buffalo, you will encounter more challenging paddling due to sandy, erodible banks and fast-growing silver maples that frequently fall and block the river. In this stretch, you may see more wildlife, but you have to work harder to get around numerous obstacles.

• List of rivers of Minnesota

Uncharacterized Protein C9orf50

Chromosome 9 open reading frame 50 is an uncharacterized gene at 9q34.11 spanning 10,051 bases, transcribing an mRNA of 1,624 bases that encodes a 431 amino acid protein of unknown function. The predicted pI and molecular weight for the protein is 10.38 and 47.6 kD respectively. The transcribed regions of this gene are on the reverse strand and is comprised of 7 exons. The C9orf50 gene contains the conserved domain in pfam15737- DUF4685, which is of unknown function and conserved in vertebrates. The gene is known to be intracellular, primarily localized to the nucleus though it has, on some occasions, been found in mitochondria and cytosol. The protein has biased expression to the testes (highest in the left testis) and brain.
An Error has occurred retrieving Wikidata item for infoboxChromosome 9 open reading frame 8 is a protein that in humans is encoded by the C9orf50 gene. This protein has a function that is not yet very well understood by the scientific community. C9orf50 has one other known alias, FLJ35803. In humans the gene coding sequence is 10,051 base pairs long, transcribing an mRNA of 1,624 bases that encodes a 431 amino acid protein.

Gene

In humans the gene is located on the minus strand at 9q34.11 and the coding sequence is 8,552 base pairs long. In the neighborhood of C9orf50 is NTMT1 gene. This gene is made up of 7 exons. On human chromosome 9, the gene spans bases chr9:132,374,504-132,383,055

Transcript

The C9orf50 gene has isoforms X1-X11.

Protein

The C9orf50 protein has a molecular weight of 47,639 Da and consists 431 amino acids. The C9orf50 protein contains the conserved domain in pfam15737- DUF4685, the function of which is not well understood and conserved in vertebrates.

Homologs

There are no known paralogs of C9orf50. Homologs of C9orf50 have been found conserved across all subclasses of mammals. This gene is not found in reptiles, amphibians, birds, or any other organisms evolved before mammals. A list of mammals in which C9orf50 is conserved is shown below.

C9orf50 Strict Orthologs

#	Common Name	Taxonomic Order	Divergence	NCBI Accession #	Protein Length (AA)	Identity (%)	Similarity (%)
1	Human	Hominini	0	NP_955382.3	431	100	100
2	Chimpanzee	Primates	6.65	XP_016817319.1	431	97.22	97
3	Gorilla	Primates	9.06	XP_018889539.1	435	93.17	96
4	Deer Mouse	Rodentia	90	XP_006983488.1	391	46.14	57
5	Prairie Vole	Rodentia	90	XP_005346778.1	370	45.18	56
6	American Pika	Lagomorpha	90	XP_004593748.1	579	38.11	48
7	Killer Whale	Cetacea	96	XP_012388229.1	343	59.34	71
8	Porpoise	Cetacea	96	XP_024617982.1	473	56.71	67
9	Alpaca	Artiodactyla	96	XP_006205645.1	399	53.83	62
10	Flying Fox	Chiroptera	96	XP_015449607.1	432	53.21	62
11	Fruit bat	Chiroptera	96	XP_015989428.1	431	53.01	61
12	Goat	Artiodactyla	96	XP_017910228.1	438	52.4	61
13	Seal	Carnivora	96	XP_025744313.1	441	52.36	60
14	Hedgehog	Soricomorpha	96	XP_007527129.1	419	51.42	58
15	Grizzly Bear	Carnivora	96	XP_026369526.1	447	50.63	58
16	Star Nosed Mole	Proboscidea	96	XP_012576659.1	383	48.68	58
17	Rhinoceros	Perissodactyla	96	XP_014637447.1	489	47.25	53
18	Elephant	Proboscidea	105	XP_023401069.1	527	49.31	59
19	Armadillo	Cingulata	105	XP_023443586.1	476	46.72	55
20	Opossum	Didelphimorphia	159	XP_007475193.1	583	32.56	52

Expression

C9orf50 overall has quite low expression, the most noticeable expression comes from testes . C9orf50 to have biased expression in cerebellum and testes, as well as female sex tissues. C9orf 50 has high expression in testis at an average of 8.1 TPM. High expression is found in round and early spermatids as well as elongated or late spermatids. There is a medium level of expression in pachytene spermatids. Protein expression was not found Leydig, peritubular, Sertoli, spermatogonia, or preleptotene spermatids. There is low expression in endometrium 1 with RNA expression of 0.2 TPM .

Splice Isoforms and Variants

C9orf50 has 10 different splice isoforms (SI) and 11 different transcript variants (TV).

C9orf50 Isoform table. Author Hannah Berhow

Motifs

Motif Start Stop Score ipfam:C1_1 516 565 9.7999997E-011 ipfam:CAMSAP_CH 19 102 3.59999989E-021 ipfam:PH 406 503 5.50000001E-009 ipfam:RhoGEF 198 371 3.20000517E-041 ipfam:SH2 671 745 2.40000003E-017 ipfam:SH3_1 617 652 2.09999996E-007 ipfam:SH3_1 788 834 3.10000003E-016 ismart:C1 516 564 4.30000008E-010 ismart:CH 3 115 3.79999987E-014 ismart:PH 403 506 1.99999999E-011 ismart:SH2 669 751 9.00000005E-026 ismart:SH3 785 841 2.90000011E-022 ismart:SH3 595 659 6.50000009E-009 Table 1. Motif Analysis from Myhits Query By Protein found 13 motifs with significant scores, <0.001.6 stuctual motifs are supersecondary strucutres which also appear in a variety of other molecules. .

Protein Interactions

C9orf50 is predicted to interact with many different proteins including CCDC81, TMEM169, ENTHD2, C17orf89, KLHL 18, IFFO1, NDRG4, SEPT9, TMEFF2,and SPG20.