User:GhasMak
Mini Muscle
[edit]A gene recently discovered in laboratory house mice, termed "mini-muscle", causes a 50% reduction in hindlimb muscle mass as its primary effect (the phenotypic effect by which it was originally identified)[1]. In addition to smaller hindlimb muscle mass, the mice exhibit lower heart rates during physical activity, and a higher endurance. Mini Muscle Mice also exhibit larger kidneys and livers. All of these morphological deviations influence the behavior and Metabolism of the mouse. For example, mice with the Mini Muscle mutation were observed to have a higher per-gram aerobic capacity[2] . The mini-muscle allele behaves as a Mendelian recessive gene.[3] The mutation is a single nucleotide polymorphism (SNP) in an intron of the Myosin heavy polypeptide 4 gene.[4]
- ^ Cite error: The named reference
Pavlicevwas invoked but never defined (see the help page). - ^ Garland, Theodore; Morgan, Martin T.; Swallow, John G.; Rhodes, Justin S.; Girard, Isabelle; Belter, Jason G.; Carter, Patrick A. (2002-06-01). "Evolution of a small-muscle polymorphism in lines of house mice selected for high activity levels". Evolution; International Journal of Organic Evolution. 56 (6): 1267–1275. ISSN 0014-3820. PMID 12144025.
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