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Epigenetic silencing and other synonymous terms: epi-silenced genes & epimutations. "Genes become aberrantly methylated in tumours through inappropriate activity of methyltransferases. Most common gene inactivation event in tumours. Can be reversed with specific drugs e.g. decitabine" Also: google reveals [www.jci.org/cgi/content/full/105/4/401 Epigenetic gene silencing in cancer Benjamin Tycko]
Li-Fraumeni syndrome reference. Especially section on pathology, perhaps split into aetiology, pathogenicity sequale etc? ;-p
My rule of wikipedia: If something would have helped me if it existed on an article, I am Bold and add it, because the chances are it will help someone else. Occasionally but mostly not disobeying other rules.1
1.^ For example, this edit goes against the manual of style by adding an internal link to a page that was already linked. However as it was an image caption, I didn't look for the link in the body of the text, so the link in the image caption would have helped me, so I added it.