User:Canesir/sandbox

Project Proposal for Pia Mater

The current Pia Mater stub includes about 2 paragraphs of information regarding the general anatomy and function of pia mater as a component of the meninges. We plan on enriching this article by initially providing a more general solid Wikipedia styled introductory paragraph, which has already been developed partially with explanations of i.e. the Latin origin of the word.

Break Down

As of right now, we plan to have the following subheadings to better explain the significance of pia mater:

Anatomy
Function
Origin
Pathology

The anatomy section will relay information regarding the location and structure of the pia mater membrane, its relation to the meninges and its components, as well as data on specific cell types found within the membrane, providing an insight to how it significantly differs from the other membranes of the meninges through i.e. proteins specific to the layer.

Using the description of the structure and anatomy of the membrane we will be able to better relay its function in the nervous system and specifically the protection of the brain.

We were looking to include a section on the Origin of pia mater, in terms of its evolutionary development. Although we have yet to find great sources for this portion it could provide a relevant timeline of development of this innermost membrane in the meninges and include whether the development of the meninges and pia mater occurred hand in hand.

Lastly, a Pathology section would include mention of some of the most serious and common diseases associated with pia mater damage or disfunction, providing the appropriate links to relevant Wikipedia pages such as Meningitis and expanding on the less common diseases not explained through Wikipedia, taking particular care to explain how the disease state affects or is linked to the pia mater.

We plan on collaborating with each other throughout the project, but have agreed that the Anatomy and Function section, being the easiest to navigate through on line, will be worked on together, especially since it is the most critical and general component that people seek out when searching for pia mater on Wikipedia. The evolutionary origin of the membrane will be researched by Sylwia and the Pathology section, which we anticipate will be the longest, will be split up between Ryan and Ryan. As a group we have agreed that there will not be rigid lines between the break up of the work and everything is subject to change. Regardless we are all responsible for our own sections.

The group has used the various encyclopedia formatted entries on a Meninges oriented website to gain background knowledge as well as some more in depth articles such as:
http://www.laserspineinstitute.com/back_problems/spinal_anatomy/spinal_cord/http://www.anesthesia-analgesia.org/content/98/5/1479.full
http://cmr.asm.org/cgi/content/abstract/5/2/130
http://chestofbooks.com/health/disease/Pathological-Anatomy/3-Inflammation-Of-The-Pia-Mater.html
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257067/pdf/janat00040-0112.pdf