User:Bervin61/sandbox
Bervin61/sandbox | |
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Virus classification | |
Group: | Group I (dsDNA)
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Family: | Adenoviridae
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Genera | |
Adenoviridae is a family of viruses . Vertebrates serve as natural hosts. There are currently 44 species in this family, divided among 5 genera. Diseases associated with this family include: human adenoviruses: mainly respiratory diseases, croup, and bronchitis, pneumonia. also keratoconjunctivitis, cystitis and gastroenteritis. fowl adenovirus C: hydropericardium syndrome (HPS) also known as angara disease. [1][2]
Taxonomy
[edit]Group: dsDNA
- Family: Adenoviridae
- Genus: Mastadenovirus
- Bat mastadenovirus A
- Bat mastadenovirus B
- Bovine mastadenovirus A
- Bovine mastadenovirus B
- Bovine mastadenovirus C
- Canine mastadenovirus A
- Equine mastadenovirus A
- Equine mastadenovirus B
- Human mastadenovirus A
- Human mastadenovirus B
- Human mastadenovirus C
- Human mastadenovirus D
- Human mastadenovirus E
- Human mastadenovirus F
- Human mastadenovirus G
- Murine mastadenovirus A
- Murine mastadenovirus B
- Murine mastadenovirus C
- Ovine mastadenovirus A
- Ovine mastadenovirus B
- Porcine mastadenovirus A
- Porcine mastadenovirus B
- Porcine mastadenovirus C
- Simian mastadenovirus A
- Tree shrew mastadenovirus A
Structure
[edit]Viruses in Adenoviridae are non-enveloped, with icosahedral geometries, and T=25 symmetry. The diameter is around 90 nm. Genomes are linear and non-segmented, around 35-36kb in length. [1]
Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
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Ichtadenovirus | Polyhedral | Pseudo T=58 | Non-Enveloped | Linear | Monopartite |
Aviadenovirus | Polyhedral | Pseudo T=50 | Non-Enveloped | Linear | Monopartite |
Siadenovirus | Polyhedral | Pseudo T=84 | Non-Enveloped | Linear | Monopartite |
Mastadenovirus | Polyhedral | Pseudo T=59 | Non-Enveloped | Linear | Monopartite |
Atadenovirus | Polyhedral | Pseudo T=25 | Non-Enveloped | Linear | Monopartite |
Life Cycle
[edit]Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral fiber glycoproteins to host receptors, which mediates endocytosis. Replication follows the DNA strand displacement model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by ribosomal shunting. The virus exits the host cell by nuclear envelope breakdown, viroporins, and lysis. Vertebrates serve as the natural host. Transmission routes are fecal-oral and air borne particles.
Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
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Ichtadenovirus | Fish | None | Glycoprotiens | Lysis | Nucleus | Nucleus | Unknown |
Aviadenovirus | Birds | None | Glycoprotiens | Lysis | Nucleus | Nucleus | Unknown |
Siadenovirus | Vertebrates | None | Glycoprotiens | Lysis | Nucleus | Nucleus | Unknown |
Mastadenovirus | Humans; mammals | None | Glycoprotiens | Lysis | Nucleus | Nucleus | Unknown |
Atadenovirus | Vertebrates | None | Glycoprotiens | Lysis | Nucleus | Nucleus | Unknown |