User:Benjah-bmm27/degree/3/GCLJ1
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Mechanisms, GCLJ1
[edit]- Reaction mechanisms
- Molecularity
- Order of reaction
- Elementary reaction
- Concerted reaction
- Stepwise reaction
- Bodenstein approximation
The philosophy behind reaction mechanism determination
[edit]According to Buskirk and Baradaran:The article's reviewers were divided on whether this is true, and most of them have published their views alongside the article itself "Can Reaction Mechanisms Be Proven?", J. Chem. Ed. (2009) 86, 551–558 |
See User:Benjah-bmm27/degree/hps.
Isotopic labelling
[edit]- Solvolysis of phenethyl tosylate, Ph-CH2-CH2-OTs, to phenethyl acetate with acetic acid
- Simple SN2 with EWGs in the para position on the benzene ring (e.g. p-NO2): ρ ≈ −1.5 (no significant accumulation of charge)
- EDGs allow a symmetrical phenonium ion intermediate to form: ρ ≈ −1.5 (no significant accumulation of charge)
- So-called assisted SN1
- Evidence for symmetrical intermediate comes from scrambling of 13C label (C) on the α-carbon of phenethyl tosylate:
- Ar-CH2-CH2-OTs → Ar-CH2-CH2-OAc + Ar-CH2-CH2-OTs