User:Benjah-bmm27/degree/2/KIBM

Introduction

"Heterocyclic Compounds", Professor Kevin Booker-Milburn

Simple heterocycles

• Heterocyclic chemistry
• Pyrrole, furan, thiophene
• Vilsmeier reaction
• Paal-Knorr synthesis

Pyrroles

• Pyrrole
• Knorr pyrrole synthesis
• Pyrrole pharmaceuticals, e.g. atorvastatin

Furans

• Feist-Benary synthesis
• Cycloaddition

Pyridines

• Pyridine
• 2-Chloropyridines are excellent electrophiles for nucleophilic aromatic substitution
• Chichibabin reaction: pyridine + sodium amide → 2-aminopyridine
• 4-Dimethylaminopyridine
• Pyridine-N-oxides
• Picolines
• Pyridinium salts
• Hantzsch pyridine synthesis
• Guareschi-Thorpe synthesis of 2-pyridone