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Vitamin D Intake Controversy

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Dr. Michael Holick another scholar known for his studies indicating that vitamin D is related to far more than bone health, and his recommendations for levels of supplemental vitamin D are as high as 10,000 IU (250μg)/d (116)—particularly in regions where exposure to sun is relatively low (150). My professor reminded me that in 2000, Michael Holick chaired the Federal panel that set the daily value at 400 IU, and still he has changed his position and is rallying for exponentially higher doses. In 1999, intake of equal to or greater than 40,000 IU (1000μg)/d was the toxic concentration level for 25(OH)D serum; however intake above 1000 IU (25μg)/d was avoided even though it was considered at least five times lower than adverse levels of intake (151). In 2007 however, the Council for Responsible Nutrition published a review of the upper limit for Vitamin D, raising it from 2000 IU to 10,000 IU based on current research indicating the many health benefits produced by adequate levels of vitamin D (http://www.ajcn.org/content/89/3/719.abstract). This year, the IOM recommended 600 IU for all adults; it seems prudent however to consider further research into the benefits of higher daily values in light of the myriad health risks and concerns associated with Vitamin D deficiency. Continued research into the risks and efficacy of high supplement intake levels is currently underway to futher elucidate how much vitamin D is not only necessary for good health, but what levels will prevent cancers, bone conditions and other immune diseases and what levels can harm the body (151).