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From Wikipedia, the free encyclopedia

Tryptophan 7-halogenase (EC 1.14.19.9PrnARebH) is an enzyme with systematic name L-tryptophan:FADH2 oxidoreductase (7-halogenating). This enzyme catalyses the following chemical reaction

tryptophan + FADH2 + Cl + O2 + H+  7-chloro-L-tryptophan + FAD + 2 H2O

In Lechevalieria aerocolonigenes the enzyme catalyses the initial step in the biosynthesis of rebeccamycin.

The enzyme can use bromide ions (Br) in place of chloride (Cl)

Is each fact referenced with an appropriate, reliable reference?

no references, not a lot of facts.

Is everything in the article relevant to the article topic? Is there anything that distracted you?

lack of facts. very very short article.

Is the article neutral? Are there any claims, or frames, that appear heavily biased toward a particular position?

no

Where does the information come from? Are these neutral sources? If biased, is that bias noted?

no sources

Are there viewpoints that are overrepresented, or underrepresented?

no

Check a few citations. Do the links work? Is there any close paraphrasing or plagiarism in the article?

no sources cited

Is any information out of date? Is anything missing that could be added?

no mechanism or structure

Is there recent research that's missing? What key names in the field don't appear in the references? 

...

How does the enzyme catalysis article compare to the way we've discussed this topic in class? 

...

How does specific enzyme article discuss catalysis? Is there a subsection about the mechanism of catalysis? 

no

What would you change about your specific enzyme article if you could?

add structure and mechanism and recent developments

Add new citations or references to the article. Are there any scholars in the field whose work is missing from this article? 

J C Lewis!

Add 3-5 new paragraphs of content backed up with citations to your article. Is there a section on "Mechanism"  and if so, is it very good? What could you add about this topic? Be sure to include conclusions from different experimental and theoretical approaches similar to the different case studies that we have considered in class. 

If there are no figures showing key aspects of the mechanism, use Pymol to construct one. Be sure to use a white background in your renderings.

Rewrite one of the paragraphs that is particularly poorly written. Make sure not to delete any links or references. 

You can copy and paste content from the live article into your sandbox space for help re-writing or framing. Just makes sure you don't delete anything!