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Daniel O. Griffin
Daniel O. Griffin (2019).
Born (1967-07-15) July 15, 1967 (age 57)
New York City, New York State
CitizenshipAmerican
Alma materUniversity of Colorado (B.A.)
New York University School of Medicine (M.D.)
Elmezzi Graduate School of Molecular Medicine (Ph.D.)
Known forTropical Diseases
HIV-1
Scientific career
FieldsBiochemistry
Molecular Biophysics
Public Health
InstitutionsColumbia University Department of Biochemistry and Molecular Biophysics
Daniel O. Griffin with Vincent Racaniello and Dickson Despommier at the recording of the This Week in Parasitism (TWiP) podcast in 2015.

Dr. Daniel O. Griffin (born June 5, 1940) is a member of the Division of Infectious Diseases and an Associate Research Scientist in the Department of Biochemistry and Molecular Biophysics at Columbia University. He also serves as the co-director of Parasites Without Borders, a global nonprofit organization with a focus on those suffering from parasitic diseases in subtropical environments.[1]

Griffin focuses his research on HIV, stem cells and the potential role that human B1 cells and natural antibodies play in the development of HIV-associated neoplasms.[2] As an expert in tropical diseases, his work also covers the clinical care of patients that reside in the New York metropolitan area as well as non-residents with a multitude of different infectious diseases.[3]

In addition to teaching and supervising medical students and fellows at the Columbia University Medical Center, Griffin is also actively involved in educating both medical and lay audiences on the internet. He is one of the hosts and a regular contributor to the highly popular scientific podcast "This Week in Parasitism"[4] (TWiP) that was originally launched by Vincent Racaniello and Dickson Despommier. He is also one of the authors of Parasitic Diseases, which is an established medical textbook dealing with basic and clinical aspects of infectious diseases.[5]

Research

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Griffin has research interest in the study of HIV-1, malignancies, and stem cell latency as well as stem cell gene therapy utilizing retroviral vectors. He is the author of over 25 scientific publications.[6]

HIV research publications

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  • Griffin, Daniel; Metzger, Michael J.; Bharti, Sheena; Dharsee, Arif; Carlos Rico, Juan; McGowan, Joseph (2016). "Co-infection with Hepatitis C Virus Increases Mortality in HIV-1 infected Patients through Increased Liver-Related Deaths Rather Than By Increasing Malignancy Related Deaths". Journal of AIDS & Clinical Research. 7 (4): 1–3. doi:10.4172/2155-6113.1000558.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  • Griffin, Daniel; Goff, Stephen P. (March 2016). "Restriction of HIV-1-based lentiviral vectors in adult primary marrow-derived and peripheral mobilized human CD34+ hematopoietic stem and progenitor cells occurs prior to viral DNA integration". Retrovirology. 13 (14). doi:10.1186/s12977-016-0246-0. PMID 26945863.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  • Rico, Juan Carlos; Schwartz, Rebecca M.; McGowan, Joseph; Griffin, Daniel (2015). "The Presence of a Malignant Comorbidity is a Significant Predictor of Increased 30-Day Hospital Readmission Rates in HIV-1 Infected Individuals". Journal of AIDS & Clinical Research. 6 (12). doi:10.4172/2155-6113.1000532. ISSN 2155-6113.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  • Griffin, Daniel; Metzger, Michael; Poeth, Kaitlin; Deng, Kathy; Dharsee, Arif; Rico, Juan Carlos; McGowan, Joseph (December 2015). "Malignancies, Particularly B-Cell Lymphomas, Are a Frequent Cause of Mortality in Human Immunodeficiency Virus-1 Patients Despite Highly Active Antiretroviral Therapy". Open Forum Infect Diseases. 2 (4). doi:10.1093/ofid/ofv147. PMID 26566539.
  • Griffin, Daniel; Rothstein, Thomas L. (May 2012). "Human "Orchestrator" CD11b+ B1 Cells Spontaneously Secrete Interleukin-10 and Regulate T-Cell Activity". Molecular Medicine. 18 (1): 1003–1008. doi:10.2119/molmed.2012.00203. PMID 22634719.

Parasites Without Borders

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Daniel Griffin is one of the five co-directors of Parasites Without Borders,[7] a global nonprofit organization founded in New York City, New York with a focus on helping those suffering from parasitic diseases in subtropical environments. The organization endeavors to reach its goal by “bringing the latest medical and basic biological information pertaining to diseases caused by eukaryotic parasites to every practicing physician and medical student within the United States."

In an effort to provide education for all those in a position to apply medical knowledge directly to populations most in need of solutions, Parasites Without Borders continues to make available, free of charge, the PDF version of Parasitic Diseases in both English and Spanish editions.[8] Originally published in 1982, the book is a conglomeration of medical knowledge on the broad topic of parasitology and disease mechanisms, diagnostic techniques, treatments, and preventive measures.

Philip J. Rosenthal, writing for the official scientific journal of the American Society of Tropical Medicine and Hygiene, lauded Parasites Without Borders for its efforts to “disseminate the book widely at no cost” and recommended the Parasitic Diseases as an appropriate text for students, senior parasitologists and other professionals that are seriously interested in the study of parasitology. [9]

In addition to Daniel Griffin, four other co-directors [10] of Parasites Without Borders include Peter Hotez, Dickson Despommier, Charles A. Knirsch and Vincent Racaniello, all of whom are scientists with a lifetime of experience in studying parasitic diseases.

COVID-19 Response

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Griffin has made a number of media appearances to offer stark warnings about the dangers to public health posed by the outbreak of the novel coronavirus.[11][12] [13][14] He has also covered the issue of ventilator shortages and the crucial role its supply plays in keeping severely-ill coronavirus patients alive.[15] Griffin also frequently appears on the scientific podcast "This Week in Parasitism" (TWiP) to educate lay audiences on the effects of the outbreak.[16]

References

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  1. ^ "Parasites Without Borders".
  2. ^ https://www.asm.org/Biographies/Daniel-Griffin
  3. ^ https://www.prohealthcare.com/locations-nav/providers/ny/daniel-griffin/1831125640.html
  4. ^ https://www.microbe.tv/twip/about/
  5. ^ https://parasiteswithoutborders.com/books/
  6. ^ https://www.researchgate.net/profile/Daniel_Griffin2
  7. ^ "Parasites Without Borders".
  8. ^ "Parasitic Diseases". Parasites Without Borders. Retrieved March 4, 2020.
  9. ^ Rosenthal, Philip J. (March 7, 2018). "Parasitic Diseases (Book Review)". The American Journal of Tropical Medicine and Hygiene. 98 (3): 933–934. doi:10.4269/ajtmh.17-1003. ISSN 0002-9637. PMC 5930926.
  10. ^ "Our Team and Mission". www.parasiteswithoutborders.com.
  11. ^ https://www.foxnews.com/health/can-you-catch-coronavirus-surfaces
  12. ^ https://www.npr.org/sections/health-shots/2020/04/02/825491635/think-youve-got-covid-19-here-s-what-doctors-say-about-when-to-seek-help
  13. ^ https://edition.cnn.com/travel/article/hiking-beach-coronavirus/index.html
  14. ^ https://time.com/5811061/drive-thru-coronavirus-testing-workers/
  15. ^ https://nypost.com/2020/04/01/coronavirus-what-is-a-ventilator-and-why-is-there-a-shortage/
  16. ^ https://www.microbe.tv/twiv/twiv-595/
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