UNKL

UNKL
Identifiers
Aliases	UNKL, C16orf28, ZC3H5L, ZC3HDC5L, unkempt family like zinc finger, unk like zinc finger
External IDs	OMIM: 617463; MGI: 1921404; HomoloGene: 62673; GeneCards: UNKL; OMA:UNKL - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,414,751 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	25,234,443 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sural nerve; ; germinal epithelium; ; right uterine tube; ; Brodmann area 23; ; right hemisphere of cerebellum; ; parietal pleura; ; left ovary; ; visceral pleura; ; right adrenal gland;
	Top expressed in
	otolith organ; ; utricle; ; trigeminal ganglion; ; cerebellar vermis; ; Epithelium of choroid plexus; ; lobe of cerebellum; ; ciliary body; ; vestibular membrane of cochlear duct; ; mammillary body; ; supraoptic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; ubiquitin-protein transferase activity; transferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; cytoplasm; cytosol;
Biological process	protein ubiquitination; protein polyubiquitination; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	64718
	74154
	ENSG00000059145
	ENSMUSG00000015127
	Q9H9P5
	Q5FWH2
NM_001037125; NM_001193388; NM_001193389; NM_001276414; NM_001367622;
	NM_001370526; NM_001372107; NM_024023
	NM_001197024; NM_001290736; NM_028789; NM_001357876; NM_001357877
NP_001032202; NP_001180317; NP_001180318; NP_001263343; NP_001354551;
	NP_001357455; NP_001359036
	NP_001183953; NP_001277665; NP_083065; NP_001344805; NP_001344806
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein unkempt-like is a protein that in humans is encoded by the UNKL gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000059145 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015127 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: UNKL unkempt homolog (Drosophila)-like".

Mohler J, Weiss N, Murli S, et al. (1992). "The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein". Genetics. 131 (2): 377–88. doi:10.1093/genetics/131.2.377. PMC 1205012. PMID 1339381.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. Bibcode:2001Sci...291.1304V. doi:10.1126/science.1058040. PMID 11181995.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. Bibcode:2004Natur.432..988M. doi:10.1038/nature03187. PMID 15616553.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000059145 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000015127 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: UNKL unkempt homolog (Drosophila)-like".

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References

Further reading