TyrT operon
The tyrT operon is a series of genes encoding the tRNA for tyrosine in Escherichia coli. It is activated in response to amino acid starvation.[1]
Components
[edit]The tyrT operon consists of an upstream activation sequence, the gene for the tyrosine tRNA called tRNA1Tyr, and an RNA called rtT RNA which has an unknown function.[1]
Regulation
[edit]Transcription of the tyrT operon is activated by the stringent response.[1] Binding of the FIS protein to the operon's upstream activation sequence tightly bends the DNA, promoting transcription.[2]
References
[edit]- ^ a b c Bosl M, Kersten H (1991). "A novel RNA product of the tyrT operon of Escherichia coli". Nucleic Acids Research. 19 (21): 5863–5870. doi:10.1093/nar/19.21.5863. PMC 329039. PMID 1840671.
- ^ Travers A, Schneider R, Muskhelishvili G (February 2001). "DNA supercoiling and transcription in Escherichia coli: the FIS connection". Biochimie. 83 (2): 213–217. doi:10.1016/s0300-9084(00)01217-7. PMID 11278071.