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Timeblock is a research project that was developed in Switzerland to discover blue zones and aging-process solutions.[1]

History and origins

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The project Timeblock began as a research project by a group of scientists from the Swiss Bluezones Research Group.[2] The term "blue zones" was created by Dr. Michel Poulain and his colleague Giovanni Mario Pes, who discovered the first blue zone in Italy: an area in which an above average number of people live to be 100 years old or older.[3][4][5]

In 1997, the Swiss Research Group started investigating lifestyles, diets and living environments in blue zones (mainly in Japan and Switzerland). Their first focus was the small village Yuzurihara. In 2007, they started to analyse 108 special species of plants for their cancer-fighting and anti-aging properties. In 2014, the Bluezones Research Group and the University of Vienna investigated secondary plant substances from blue zone regions (mainly Tibet and Nepal-Himalayas) growing in remote areas and high altitudes to show that Timeblock can slow down cell rejuvenation by lengthening telomeres 17%.[6][7]

Timeblock has two main product lines: Nutrition Care (Nutraceuticals) and Facial Care (Cosmeceuticals), which is claimed to remodel a person's epigenome in order to optimize the individual DNA.[8][9] Their Nutraceuticals capsules are vegan, non-GMO, gluten-free, lactose-free, and free from chemical preservatives made of plants such as barley grass, green tea (epigallocatechin gallate), wheatgrass, shiitake mushrooms (vitamin D), marigold (zeaxanthin and lutein), grape seeds (flavonoids), tomatoes (lycopene), brown algae (omega-3).[10][11] Cosmeceuticals lotion contains equol, IGF-1 and EGF (insulin-like growth factor and epidermal growth factor), epigallocatechin gallate, microalgae extract and Âmeflore essential oils to promote cell renewal and regeneration to counteract the signs of aging.[12][13]

The active substance in Timeblock Skin Care is equol. The topical effect of equol as an anti-aging and skin health improving substance was shown in different studies. Equol can occur as different isomers: R-equol, S-equol and RS-equol. Each of these forms has different characteristics, bioavailabilities and molecular effects.[14] As an antioxidative operating substance, equol can decrease the aging process by reducing ROS events. Additionally, the phytoestrogenic properties positively influence the skin health.[15]

Awards

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In 2019, TimeBlock won Global Health and Travel Awards "Product of the Year" award.[16]

See also

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References

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  1. ^ "Direkt vom Hersteller TimeBlock Anti-Aging Kapseln". TimeBlock Anti Aging (in German). Archived from the original on 2022-01-13. Retrieved 2022-01-13.
  2. ^ rcastro05 (2020-10-07). "Renowned Swiss Beauty Brand, "timeblock," Launches in the U.S." Miami Living. Archived from the original on 2022-01-15. Retrieved 2022-01-13.{{cite web}}: CS1 maint: numeric names: authors list (link)
  3. ^ Poulain, Michel; Pes, Giovanni Mario; Grasland, Claude; Carru, Ciriaco; Ferrucci, Luigi; Baggio, Giovannella; Franceschi, Claudio; Deiana, Luca (2004). "Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study". Experimental Gerontology. 39 (9): 1423–1429. doi:10.1016/j.exger.2004.06.016. ISSN 0531-5565. PMID 15489066. S2CID 21362479.
  4. ^ Deiana, L.; Ferrucci, L.; Pes, G. M.; Carru, C.; Delitala, G.; Ganau, A.; Mariotti, S.; Nieddu, A.; Pettinato, S.; Putzu, P.; Franceschi, C. (1999). "AKEntAnnos. The Sardinia Study of Extreme Longevity". Aging Clinical and Experimental Research. 11 (3): 142–149. doi:10.1007/bf03399655. ISSN 1720-8319. PMID 10476308. S2CID 7088801.
  5. ^ Schaeffel, Frank (1999). "Das wachsende Auge - ein optisches System mit Autofokus". Biologie in unserer Zeit. 29 (4): 238–246. doi:10.1002/biuz.960290407. ISSN 0045-205X.
  6. ^ KOMORI, TOYOSUKE (1984). "Looking back of studies on the long life village "Yuzurihara". - Especially upon the relation-ship between long life and bacterial situation in intestine". Japanese Journal of AMHTS. 11 (3): 199–209. doi:10.7143/jhep1975.11.199. ISSN 1884-4081.
  7. ^ Poulain, Michel; Herm, Anne; Pes, Gianni (2013). "The Blue Zones: areas of exceptional longevity around the world". Vienna Yearbook of Population Research. 11: 87–108. doi:10.1553/populationyearbook2013s87. ISSN 1728-4414. JSTOR 43050798. Archived from the original on 2022-01-13. Retrieved 2022-01-13.
  8. ^ Limited, Media OutReach (2017-02-14). "TimeBlock -- Breakthrough Science-based 'Elixir of Youth' Proven To Reverse Biological Ageing Launches In Singapore". GlobeNewswire News Room. Archived from the original on 2022-01-13. Retrieved 2022-01-13. {{cite web}}: |last= has generic name (help)
  9. ^ Iten, Jocelyne. "Supplementieren: Das Geschäft mit den Schönheitspillen boomt". NZZ Bellevue (in German). Archived from the original on 2022-02-09. Retrieved 2022-02-09.
  10. ^ "Green Tea Linked To Skin Cell Rejuvenation". ScienceDaily. Archived from the original on 2022-01-15. Retrieved 2022-01-13.
  11. ^ "The effects of aging on your skin on MedicineNet.com". MedicineNet. Archived from the original on 2022-01-13. Retrieved 2022-01-13.
  12. ^ "Ethnic Differences in Skin Sensitivity and Responses to Topically Applied Products", Sensitive Skin Syndrome, CRC Press, pp. 71–78, 2006-05-16, doi:10.3109/9781420004601-8, ISBN 978-0-429-12504-1, retrieved 2022-01-13
  13. ^ "TimeBlock - Plant-based anti-ageing product proven to decrease biological age". Verita Quantum Health. 2017-10-11. Archived from the original on 2022-01-13. Retrieved 2022-01-13.
  14. ^ Lephart, Edwin D. (2013-11-01). "Protective effects of equol and their polyphenolic isomers against dermal aging: Microarray/protein evidence with clinical implications and unique delivery into human skin". Pharmaceutical Biology. 51 (11): 1393–1400. doi:10.3109/13880209.2013.793720. ISSN 1388-0209. PMID 23862588. S2CID 207526265.
  15. ^ Lephart, Edwin D. (2016). "Skin aging and oxidative stress: Equol's anti-aging effects via biochemical and molecular mechanisms". Ageing Research Reviews. 31: 36–54. doi:10.1016/j.arr.2016.08.001. ISSN 1872-9649. PMID 27521253. S2CID 205668316. Archived from the original on 2022-02-10. Retrieved 2022-02-10.
  16. ^ "AWARDS". mysite. Archived from the original on 2022-02-09. Retrieved 2022-02-09.
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