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Prepared template changes

Changes implied. Discussion closed. Later comments are welcome in #Post-edit comments. -DePiep (talk) 20:17, 22 March 2015 (UTC)

The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

I have prepared several changes to this template. Most are code and maintenance completion & streamlining.

Useful links
Parameter & visible changes
  • No more "?" showing for bad input.
Currently, some major parameters show a "?" when input is missing or not recognized: |type=mab |source=, |ATC=, |legal_status...=, |formula=. The question mark will not show any more. In general, we should not show maintenance notes as content data. Those articles are categorized for maintenance.
  • Country abbreviations are explained as abbr but not linked: US. eg in |legal_status_US=.
  • Redlink categories removed from code. Following this 2012 CfD, some categories are removed. Interestingly, those categories do not exist (ie, were redlinkend) and were empty (no articles). Eg: Category:European Union controlled drug precursors.
  • |legal_status_XX= and |pregnancy_category_XX= input that is not by list (such as: Scheme I) is categorized to check.
Bot assisted validation

CheMoBot validation: The bot checks seven identifying parameters for verification. From this, the bot may add a parameter & value like: |CAS_number_Ref={{cascite}}. This parameter adds the checkY or ☒N notification.

  • Changed: |DrugBank_Ref= is added to the template, so that all seven identifiers work alike (effect: now |DrugBank= shows its checkY/☒N verification quality). The bot working itself is not changed. See Chemicals validation and {{cascite}} for general bot activities and effects.
The set of seven bot verified identifiers now is identical with those of {{Chembox}}. Also, their maintenance categories are the same (one category is filled by the two templates).
  • Articles missing such an identifier is categorized too. This too is the same as with {{Chembox}}.
In code
  • Code into satellite subtemplates. Some large code blocks are separated into subtemplates: |type=mab, |ATC=, |legal_code_XX=, |pregnancy_category= This way the main template is easier to overview and maintain. This split off in itself does not change the visual result.
  • The chemical formula entered by |C=, H=, O=, ...= is made stand-alone template for common usage {{Chem styled}}, from talkpage request. This split off in itself does not change the visual result. Made it into subtemplate {{Infobox drug/chem styled}} now, to keep it under {Drugbox} control. Some issues make it unfit for general use imo: font coloring & bolding, incompleteness, limited to organic. -DePiep (talk) 09:44, 22 March 2015 (UTC)
  • Articles using non-existant parameters are categorized for maintenance check. This wrong parameter name could be a typo. In Preview, the wrong parameter is mentioned in a red error message. See also doc/parameter list.
More on maintenance categories
  • The maintenance category tree is reorganised into a more systematic tree setup (already in effect). The category trees are set up in parallel with the {{Chembox}}.
  • Only articles will be categorized. (Note: for testing purposes, testcases now show maintenance categories readible).
  • Several maintenance categories are added or renamed (unknown legal code, no legal code by country; see also the "?" change mentioned above).

Any remarks? -DePiep (talk) 00:47, 14 March 2015 (UTC)

I will suggest to add some @@@ for maintenance (suggested at Wikipedia_talk:Chemical_infobox#Bad_parameter_names:_categorized too) - that way its easy to see where the problem is, and normal readers doesnt see it. Like the citation template does. Christian75 (talk) 11:04, 14 March 2015 (UTC)
As I replied there, some reasons to postpone this. The good news is that {Drugbox} is a single template, while {Chembox} has 9 subtemplates in the |SectionN= structure. {Chembox} required a lot of extra maintenance for this, while {Drugbox} has not.
But other responses are valid here too: 1. that option better be in the core module anyway (as Cite/CS1 has). 2. error messaging is not fully perfect. |errNS= interacts with |format= and |preview=, which makes it complicated and the module maintainer (dewiki) has noted this might change (see my talks over there). 3. This messaging is just one of the cleanup actions I am working on. Building and of course testing this would be another chuck of serious work (don't want to spoil 8000 articles with errormessages), while it does not to add to the core maintenance job. ({Chembox} categorizes these errors too, and there is not much correcting activity). In other words, a lot of work that is not required.
For these reasons, I choose to postphone this (good) idea. -DePiep (talk) 09:09, 16 March 2015 (UTC)
  • Preparing to go live.
Most useful changes to be expected in Category:Infobox drug maintenance categories, and some visual changes. Other changes are in template background. -DePiep (talk) 20:00, 22 March 2015 (UTC)
The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

Post-edit comments

Useful link: Category:Infobox drug maintenance categories

The Drugbox calls /sandbox Christian75 (talk) 20:24, 22 March 2015 (UTC)

Will check this, but please be more specific right away. Page? -DePiep (talk) 21:02, 22 March 2015 (UTC)
@DePiep: Template:Drugbox, just search for "sandbox" and you will find it :-) Christian75 (talk) 21:18, 22 March 2015 (UTC)
So I checked WLH for Template:Drugbox/sandbox: [1]. For now, I think you saw "late changes" (wikipedia delays). If you see any page (article) that keeps using a /sandbox, please mention it. -DePiep (talk) 21:29, 22 March 2015 (UTC)
No, template:Infobox drug calls /sandbox - try to preview (edit and then "show preview" of the article) a drugbox article, e.g. Sodium_thiopental and you will see the error "Error in template * unknown parameter name (Template:Infobox_drug/sandbox): 'InChI; CASNo_Ref'", because the infobox calls /sandbox. Go to [2] and search for sandbox (its in the section you call "Parameter check"). Christian75 (talk) 21:46, 22 March 2015 (UTC)
"No, template:Infobox drug calls /sandbox " - which /sandbox page is that? Why don't you just provide a link?
Sodium_thiopental opened for edit and then preview does not mention any ../sandbox page.
[3] The 'InChI; CASNo_Ref'" you mention is not a /sandbox issue. It is a correct mentioning of unknown parameters. That's TemplatePar working. -DePiep (talk) 22:08, 22 March 2015 (UTC)
@DePiep: - The drugbox have -->{{#invoke:TemplatePar
|check
|template=Template:Infobox_drug/sandbox
Sandbox in bold.
I really thought that was a mistake, and the output I printed says /sandbox too. When you preview the article doesnt you see: "Error in template * unknown parameter name (Template:Infobox_drug/sandbox): 'InChI; CASNo_Ref'"? Christian75 (talk) 22:31, 22 March 2015 (UTC)
I see! Done: [4]. You are right, please understand that it took some research & thinking to find this. Thanks for pursuing me in this ;-). -DePiep (talk) 22:40, 22 March 2015 (UTC)
Chris75, hat this one? -DePiep (talk) 22:50, 22 March 2015 (UTC)
Yes its gone now... Christian75 (talk) 12:23, 23 March 2015 (UTC)
See legal status documentation

For all options for all countries and institutes, please take a look at the completed documentation. That is: AU, CA, NZ, UK, US, UN, EU. All have the option Unscheduled added. -DePiep (talk) 20:57, 3 April 2015 (UTC)

  • Added: |legal_AU=Unscheduled for all. Is recognised (but not wikilinked).
  • Added: |legal_AU_comment= for all. Will be added, with a space prefixed, right after the listed value. A _comment is not edited (no brackets, no italics). -DePiep (talk) 18:00, 6 April 2015 (UTC)
  • I think it would be good to add a clarification to the coded words. For example:
(with opium)

That would need some text proposals. -DePiep (talk) 12:13, 7 April 2015 (UTC)

 Done. See also Category:Drugs with non-standard legal status (loads of "Rx-only" without country specification). DePiep (talk) 20:47, 9 April 2015 (UTC)

Triggerend by todays Featured Article Amphetamine, I found that we can improve the UK legal status information, by template. In the sandbox, I have prepared this new set for |legal_UK=.

Notes and questions:

  • Added/changed: links and more readable text for the GSL/P/POM codes.
  • Added: Class A, B, C as new option. See their links.
  • Added a link for the CD set. But I could not find what these categories actually are. Is there any good source that lists them?
  • Today, there are ~80 articles in Category:Drugs with non-standard legal status for the UK. That is, their input is not in the live list today (eg, "Class A" is not yet in there). The additions shold reduce this number.

Any remarks? -DePiep (talk) 14:13, 3 April 2015 (UTC)

In the documentation are the options for |legal_US=. Category:Drugs with non-standard legal status has ~100 under "S" (for "US"), which is rather high.

Notes

Added to demo sandbox. -DePiep (talk) 19:30, 3 April 2015 (UTC)

Some drug articles have added a |legal_status= text for New Zealand. Since this is an English-speajking country, I think we should add NZ to the list of pre-formatted coutnries (with AU, CA, UK,US, UN, EU).

Sources: Misuse of Drugs Act 1975
Options (proposals): see documentation
Any remarks? -DePiep (talk) 16:19, 3 April 2015 (UTC)

Pregnancy category check

The pregnancy category classification (for AU and US) can use a check. The options are documented with Template:Infobox drug/pregnancy category. Newly added: |pregnant_AU_comment=, (for AU, US). Comments? -DePiep (talk) 19:33, 7 April 2015 (UTC)

 Done. See also documentation and Category:Drugs with non-standard pregnancy category. -DePiep (talk) 20:50, 9 April 2015 (UTC)

Template-protected edit request on 26 May 2015

Please change the only instance of "{{long item" to "{{longitem". The template {{longitem}} is used eight other times in this template, with the latter form being used each time. This change will not affect the functionality of the template at all; it will allow for better use of the "what links here" tool and other similar features.


Excerpt of current code (instance to be changed is in the 1st line; the 4th line shows one of the other eight instances): 

| label40 = {{long item|1=[[CAS Registry Number]]}}
|  data40 = {{#if: {{{CAS_number|}}} | <span class="reflink plainlinks nourlexpansion">[//www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?term={{{CAS_number}}}&rn=1 {{{CAS_number}}}]</span> }}{{{CAS_number_Ref|}}} {{{CAS_supplemental|}}}

| label41 = {{longitem|1={{#ifeq:{{lc:{{{ATCvet}}}}} | yes | [[Anatomical Therapeutic Chemical Classification System#ATCvet|ATCvet code]] | [[Anatomical Therapeutic Chemical Classification System|ATC code]]}} }}
|  data41 = {{Infobox drug/ATC |ATCvet={{{ATCvet|no}}} |ATC_prefix={{{ATC_prefix|}}} |ATC_suffix={{{ATC_suffix}}} |ATC_supplemental={{{ATC_supplemental|}}} }}

Please change it to: 

| label40 = {{longitem|1=[[CAS Registry Number]]}}
|  data40 = {{#if: {{{CAS_number|}}} | <span class="reflink plainlinks nourlexpansion">[//www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?term={{{CAS_number}}}&rn=1 {{{CAS_number}}}]</span> }}{{{CAS_number_Ref|}}} {{{CAS_supplemental|}}}

| label41 = {{longitem|1={{#ifeq:{{lc:{{{ATCvet}}}}} | yes | [[Anatomical Therapeutic Chemical Classification System#ATCvet|ATCvet code]] | [[Anatomical Therapeutic Chemical Classification System|ATC code]]}} }}
|  data41 = {{Infobox drug/ATC |ATCvet={{{ATCvet|no}}} |ATC_prefix={{{ATC_prefix|}}} |ATC_suffix={{{ATC_suffix}}} |ATC_supplemental={{{ATC_supplemental|}}} }}

Jdaloner (talk) 07:11, 26 May 2015 (UTC)

Red X 10pxN Not done. {{long item}} redirects to {{longitem}}, so the templates behave exactly the same. The edit would have no effect on an article, so this is a cosmetic edit.
However, I expect to edit the template in the coming weeks for this topic of molecular weight. I've made this edit in the sandbox [6], and it will hitchhike with that substantial edit. -DePiep (talk) 07:31, 26 May 2015 (UTC)
I like to add that this edit request by Jdaloner is written very well. -DePiep (talk) 20:05, 26 May 2015 (UTC)

Split the formula highlighter into a separate template?

Right now the template uses a wrapper for {{OrganicBox_atom}} to element-highlight the chemical formulas. This is extremely bulky with every single element a different color, and therefore I feel the module is a good candidate to be separated into a different template. This would also make the code reusable in other pages like List of compounds with carbon number 10 which is in grave need of some colors. Please {{reply to}} me so I don't need to constantly check my watchlist. Timothy G. from CA (talk) 05:38, 9 December 2014 (UTC)

@Timothy Gu:. I assume you mean to split the formula code into a separate template or module (so this drugbox can call something like: {{OrganicBox_molecule|H={{{H|}}}|C={{{C|}}}}}). Technically this would be OK.
But for {drugbox}, I'd propose to do the opposite: do not color the element symbols at all (and do not bold them). First, the color distracts me. I do know what a chemical formula looks like, but I have no clue about the colors. To me it looks like there is something going on I don't know. Already the plain links in H2SO4 (as {{Chembox}} has) is a stretch in readibility & recognisability. Second, it is not clear what the color means to say (Does there exist a red oxygen?). There is no clarification (key) at hand. For accessability (and good page design) , WP:COLOR says: "Ensure that color is not the only method used to convey important information". It may feel like stepping back, but preventing colors used as a form of fancy brightening the page makes good articles. -DePiep (talk) 22:57, 17 December 2014 (UTC)

Need a new field

Our drugbox currently includes a parameter for dependence liability, but not addiction liability. Since there's a definitional and induction mechanism distinction between the two, and since people often confuse the terms, it seems necessary to include an addiction liability drugbox parameter/field. Caffeine is the most obvious article that comes to mind where these are different. This[1] covers a few more examples. Seppi333 (Insert 2¢ | Maintained) 05:04, 8 January 2015 (UTC)

References

  1. ^ Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 15: Reinforcement and Addictive Disorders". In Sydor A, Brown RY (ed.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill Medical. pp. 364–368. ISBN 9780071481274. The defining feature of addiction is compulsive, out-of-control drug use, despite negative consequences. ...
    Addictive drugs are both rewarding and reinforcing. ... Familiar pharmacologic terms such as tolerance, dependence, and sensitization are useful in describing some of the time-dependent processes that underlie addiction. ...
    Dependence is defined as an adaptive state that develops in response to repeated drug administration, and is unmasked during withdrawal, which occurs when drug taking stops. Dependence from long-term drug use may have both a somatic component, manifested by physical symptoms, and an emotional–motivation component, manifested by dysphoria. While physical dependence and withdrawal occur with some drugs of abuse (opiates, ethanol), these phenomena are not useful in the diagnosis of addiction because they do not occur with other drugs of abuse (cocaine, amphetamine) and can occur with many drugs that are not abused (propranolol, clonidine).    {{cite book}}: CS1 maint: multiple names: authors list (link)
If this is supported, I can add it. (I can't say anything about its relevance). What would the lefthand text be? -DePiep (talk) 06:29, 8 January 2015 (UTC)
"Addiction liability" is adequate - might as well use the same term as used in the dependence field for consistency. Drug addiction redirects to the current dependence liability parameter's link, but the distinction between the two concepts is prominently noted in the article lead; so for the parameter wikilink, either drug addiction or addiction would be suitable. Seppi333 (Insert 2¢ | Maintained) 12:30, 8 January 2015 (UTC)
All looks well based to me, the ref is in the target article. |addiction_liabiliy= shows below dependency now, see Testcases. Same documentation I guess. Will push it live tomorrow, if the winds don't turn. -DePiep (talk) 22:01, 8 January 2015 (UTC)

WholeNewJourney, I have read your contribution to this talk about splitting Substance_dependence. Do I understand that you would not oppose adding this second parameter |addiction_liabiliy= next to |dependency_liabiliy=, as they are distinct (however difficult to describe that in article(s))? Please note that we will not repeat that discussion here. This is just about the {drugbox} parameter. ping Seppi333 -DePiep (talk) 10:01, 9 January 2015 (UTC)

There is too much overlap with addiction and dependence, so I don't support it (although I am open to being convinced otherwise). What I would support is a dependence liability and abuse liability parameters. If something has a high abuse potential then it also has a high behavioural addiction potential although it is possible to abuse drugs without being addicted to them - there is no perfect solution. Most authoritative sources would use such separation, think of drug package inserts that title their warnings under 'Abuse and Dependence' headers.--WholeNewJourney (talk) 20:01, 10 January 2015 (UTC)

hm. 'abuse' introduces a judgement (good/bad border), which complicates matters without solving. Isn't drug abuse simply another issue altogether (re LD50)? Also, might that abuse in the wrapper include (physical) dependency too? My impression is that the separation physical and behavioural liability makes sense. In general, an overlap is not prohibitive to describe two effects, as long as we understand that. (A bit like temparature outside and perceived/felt temperature). -DePiep (talk) 20:32, 10 January 2015 (UTC)
It does introduce a judgement issue and some recreational drug users don't like to be labelled drug abusers but that is how the majority of academics, healthcare professionals researchers etc view such use of drugs. Drug abuse is not the same as LD. Many controlled drugs have low toxicity. Abuse potential refers exclusively to the potential of a drug to induce euphoria/feelings of well-being and thus behavioural addictive potential.--WholeNewJourney (talk) 01:36, 11 January 2015 (UTC)
I don't see ehat that extra judgements adds, not even for these academics. Maybe "abuse" should have a third parameter, re social judgement. (you ruled out that abuse is related to toxic LD, a more rational one). So far, I still have not gotten why behaviour angle would not do. -DePiep (talk) 01:46, 11 January 2015 (UTC)
Granted the abuse parameter draws in more problems. My problem is that the definition of addiction and dependence overlap significantly (dependence liability covers both behavioural addiction and physical dependence) and it is confusing area even for academics and most of our readers are lay people. One solution (and perhaps the best solution?) would be to have addiction liability and change dependence liability to physical dependence liability. That would make things less confusing for our article readership. What do you think?--WholeNewJourney (talk) 05:40, 11 January 2015 (UTC)

...a behavioral addiction is literally just an addiction to a natural reward (i.e., a non-drug addiction)... it describes nothing more than the class of addictive stimulus (a "non-drug" one). I'm just going to hope you understand the issue with the current characterizations of these concepts by the DSM and other entities after reading my reply on the other talk page... Seppi333 (Insert 2¢ | Maintained) 07:56, 11 January 2015 (UTC)

Thank you for correcting my mistake regarding behavioural addiction. You never passed comment on having addiction and physical dependence parameter. Good or bad idea?--WholeNewJourney (talk) 10:58, 11 January 2015 (UTC)
Many stimulants don't cause physical dependence, but psychological dependence instead, so it may be better to simply leave it as is; changing it to physical dependence would necessitate changing the parameter values in some articles to correctly reflect their physical dependence liability vs (general) dependence liability. Seppi333 (Insert 2¢ | Maintained) 16:30, 12 January 2015 (UTC)

Change request

Please change

vaccine = [[Vaccine|Vaccine description]]

to

vaccine = [[Vaccine]] description

as a clearer wikilink. Thanks. 80.189.8.54 (talk) 16:38, 16 February 2015 (UTC)

 Done. Seems uncontroversial, but this change is revertible on request. Cheers — Martin (MSGJ · talk) 16:43, 16 February 2015 (UTC)
Undid. Since no thoughts are exchanged, I don't feel the need to add one. If TE edits are made this way, I am not invited to take care anyway. -DePiep (talk) 00:26, 17 February 2015 (UTC)
I don't understand the sentence above. The OP gave his/her rationale, and it is irresponsible to revert without providing a reason. This change was made in line with WP:BOLD - you are well within your rights to revert, but the next step in the BRD cycle is to "discuss". Regards — Martin (MSGJ · talk) 08:28, 17 February 2015 (UTC)
(As for reverting: I simply reacted to you 1st sentence "Seems ..."). I don't think this proposal is more clear. The article vaccine does not clarify the full label text, whatever the wikilabel (pipe linked) is. Also, the tempalte documentation does not hep clarifying; it does not even say which input parameter is used. So we need a better target for this one: that is the clarification needed. Until then, and practically, WP:MOSLINK (linkstyle, underlink, specific link) suggests that better link the whole term, not cut it up. (Signed days late+ping: @MSGJ:) -DePiep (talk) 10:21, 20 February 2015 (UTC)

What maintenance categories do we want?

At the moment, the set of maintenance categories is a bit chaotic. I am about to clean that up. My question is: how to organise?

These categories have parallels with {{Chembox}} and can be used.

  • Now for ATC, we can set up categories for these situations:
ATC = none
ATC = (some identifier)
ATC = <blank>
  • And, for legal issues, there is the set-list:
legal_US = none
legal_US = Schedule I
legal_US = <blank>
legal_US = some unknown free text

Some of these situation show a question mark in the article. The question is: which situations do we want in category('s)? All three/four options categorised? -DePiep (talk) 10:37, 20 February 2015 (UTC)

a lot of drugs arent chemicals, but mixture of chemicals, and IMHO the categories shouldnt be mixed with the infobox chemical's categories. Christian75 (talk) 17:52, 8 March 2015 (UTC)
Christian75, this is earthshaking news for my overview of {{Drugbox}} and {{Chembox}} articles (because: some Drugbox articles then can not be Chembox (=chemicals) articles). Those Drugbox articles do not allow merging with a universal Chembox. In short. (Ask if you prefer more explanation).
However. For this moment, and for these individual parameters, this is no issue. We can make maint cats for ATC-code and legal_US &tc without going against your statement. -DePiep (talk) 19:02, 8 March 2015 (UTC)
Im not really sure what you mean. But are you suggesting merging the chembox with the drugbox? Im strongly against that (I will spare the arguments if that isnt you intention). 11:06, 14 March 2015 (UTC)
Yes, a merge is a long term view. -DePiep (talk) 18:38, 14 March 2015 (UTC)
Christian75. About "drugs [that are a] mixture of chemicals". Isn't that already covered in {drugbox}, by setting |type=combo? (See this in the /doc). So if I'm correct, that mixture must be & will be covered (handled) in any merged template. It may be a puzzle, but not a blocker. (Can't find an example article now). -DePiep (talk) 08:15, 16 March 2015 (UTC)
  • re Christian75, about mixed categories for {Drugbox} and {Chembox}. That is, a single category that has articles added by both {Chembox} and {Drugbox}. These are the backgrounds for this. The example is CAS RN. First: CheMoBot (chemicals validation) adds a category by adding CAS_number={{cascite|changed|??}} for both boxes (see also the {{cascite}} /doc). The reason for adding is the same: verified data (the CAS RN) is changed compared to an earlier, verified article version (or, the article was never verified so far). Since the topic is the CAS RN, not the 'drug' or 'chemical' itself, the cat reason is the same. Check-the-CAS_RN is a maintenance task independent of the drug/nodrug indication. Parallel to this, the categorization "chemical/drug without CAS RN" is also fully shared, for the same reason. (However, this is done by the template not by the bot).
If those categories should be separated (they never were), the bot workings must change. I don't see that useful for reasons given, and because the bot validation process may be outdated (it needs re-activating, or wikidata should be involved, or something else).
I note that this setup is not changed by my recent edits (edits in {Chembox} and proposed edits in {Drugbox}). What I did do is bring it all in line: apply the same to all seven verified parameters for both templates (improve cat name, reorder cat tree, make all seven complete, make all seven act similar and such). I do not intend to change bot behaviour, just to make it work OK.
If one would want to work on "CAS RN in {Drugbox} only", we should provide an url link in that cat (eg using WP:CATSCAN, 'list all articles in this can that have {Drugbox} transcluded').
Infobox-specific issues (like: unknown parameter used in {Drugbox}) are kept in separate categories.
  • I add, about ATC codes. ATC is not in the list of seven bot-tracked validated parameters (see {{cascite}} for the list). At the moment, I propose to have those ATC issues categorized in Category:Drugs not assigned an ATC code, by {Drugbox} and by {Chembox} alike. (So that is a shared category too). Reasons are the same: if one wants to work or search the ATC-status for chemicals (usually but not always having {Drugbox}, today), that is you single goto page. Here too the (wiki)-difference {Drug-} or {Chem-} is not relevant. Note that the category is not hidden, because it is of readers interest. -DePiep (talk) 08:58, 16 March 2015 (UTC)
copy/pasted here, to talk central. Notify @Sizeofint: -DePiep (talk) 09:10, 10 April 2015 (UTC)
Conflict with drugbox recommendations

It says here regarding universal legal statuses "The input should be more precise (for example: "Usually prescription only in Asia". However Template:Infobox_drug says in the legal status section "if a drug is restricted everywhere to prescription-only, please set legal_status = Rx-only rather than similarly define for each and every country". It seems these need to be made consistent. Sizeofint (talk) 03:15, 10 April 2015 (UTC)

Yes that is a (new) contradiction. We should work this out. My point is: writing "legal status = Rx-only" without country/UN/EU specifier is not good information. There is no institute that can declare a drug Rx-only worldwide. I think it must be more specific in the drugbox articles (the maint category lists some 600 drug articles that say plain "Rx-only" this way).
So I propose to declare this bare notion |legal_status=Rx-only deprecated, and require a more descriptive text. That would be a maintenance task. The documentation (you quote) should be adjusted right away. -DePiep (talk) 09:16, 10 April 2015 (UTC)
I don't have a problem with that proposal. It should probably be posted to the project talk page however. Sizeofint (talk) 14:59, 10 April 2015 (UTC)
Which project page? -DePiep (talk) 18:41, 10 April 2015 (UTC)
Probably PHARM or possibly MED because the latter seems to be more active. Since there are so many articles with this usage others may have input. Sizeofint (talk) 20:35, 10 April 2015 (UTC)
Do invite them. I don't mind. I say: |legal_status=Rcx-only is bad code. -DePiep (talk)

PLLR, June 2015: new US pregnancy drug labeling

By FDA. Per June 30, 2015 the US Pregnancy and Lactation Labeling Final Rule (PLLR) comes in effect. [7]. More info [8] [9]. We'll have to check this out. -DePiep (talk) 19:38, 7 April 2015 (UTC)

Started a topic at WT:PHARM, PLLR. -DePiep (talk) 20:27, 11 April 2015 (UTC)
Proposal and demo, see Template_talk:Infobox_drug#Add_PLLR_.28US.2C_pregnancy.29. -DePiep (talk) 22:53, 26 May 2015 (UTC)

Add PLLR (US, pregnancy)

Last December, the US decided to add a new law in labeling pregnancy-related drugs. It is called PLLR. I propose to add |PLLR= as a new parameter to {{Drugbox}} and {{Chembox}}. It will appear with Pregnancy category, US.

PLLR = Pregnancy and Lactation Labeling Final Rule
  • PLLR is a labeling requirement for the US, controlled by FDA.
  • PLLR covers "pregnancy, lactation, females and males of reproductive potential".
  • PLLR labeling requirement depends of the date of drug registration.
  • For new medicines, it is required by 1 July 2015. Older drugs may keep the Category classification labeling. So there is an overlay period (many years both will exist).
Current Pregnancy categories
  • There is not simple correspondence with existing Pregnancy categories for US. Think: the medicine label must be written anew. We can not simply re-translate a US "B" category into a PLLR phrase.
Template relevance
  • PLLR text can not be mixed with Pregnancy categories.
  • Given the time overlap with old Category classification, we keep US's PLLR and Pregnancy Category separated.
  • Little is known about the structure of a PLLR text. We best start with a free text parameter.
  • In the future, PLLR free text input could be analysed and reformed into more structured input (-parameters).
  • Infobox {{Chembox}} should and can follow this, as it already copies Pregcat input. In this, {{Drugbox}} is leading over {{Chembox}}.
Resulting proposal
demo-1 (current sandbox)
Clinical data
Pregnancy
category
  • AU: B1
  • For now, we add |PLLR= as a separate parameter (belonging to the US Pregnancy category subtopic).
  • PLLR is shown in the larger "Pregnancy category" data block (including AU etc.), and in a separate row.
  • Old PregCat and new PLLR input do not interact. They simply are shown both.
  • PLLR can be added as plain text. It is not re-formatted. In=Out.
  • The wikilink "PLLR" now links (redirects) to a subsection. That redirect page can be changed easily.
Tests and Demo

I propose to add |PLLR= this way. Comments? -DePiep (talk) 22:32, 26 May 2015 (UTC)

Have you seen examples of the types of wording that will be used? Doc James (talk · contribs · email) 01:23, 27 May 2015 (UTC)
Really, I haven't. I did not even see simple plain examples, with or without structure. (I honestly ask: did you?). Let alone that I could discover a structure in there. Also the time line is suspicious: since the decision in December 2014, no editor Talked. So I decided best would be to keep PLLR separate, allow it as such, US-tied, unedited text right below any US-PregCat text. See what happens. If you see improvements, please say so. -DePiep (talk) 01:57, 27 May 2015 (UTC)
logic dictates it falls upon the poster (not those who give opinions ) to make certain they have "seen" any type of wording--Ozzie10aaaa (talk) 11:53, 27 May 2015 (UTC)
No. I've seen the law described, that's enough for this. And I have not seen any useful structure in there, so I've not implemented any structure. What's missing for you? -DePiep (talk) 16:52, 27 May 2015 (UTC)
you've answered all my questions. thank you--Ozzie10aaaa (talk) 17:55, 27 May 2015 (UTC)

Automating molecular weight using formula

The chemical-data section has the option of the chemical formula with the coefficient each element as its own parameter. If the template has that information, it can calculate the molecular weight automatically rather than an editor having to calculate or look up the value and pass it explicitly in a separate field. The chembox template suite already has this feature. Can we add it to drugbox? DMacks (talk) 20:07, 9 May 2015 (UTC)

Yes we can. Will only work when the formula is entered using the |C=, |H=, ... params, not with pre-formatted input |chemical_formula= (is what you already pointed at).
A question. When the drugbox has the mass entered by |molecular_weight=, which value should be shown: calculated or entered? -DePiep (talk) 20:59, 9 May 2015 (UTC)
The logic in {{Chembox Properties}} appears to be "if formula entered in separate parameters, use {{Chembox Elements}} to display both the formula and the calculated mass; else use unified formula field and explicitly entered mass". That is, calculated value takes priority. Both of these templates should have error checking to catch when a formula is passed both ways and when an explicit weight is passed but ignored due to calculation taking priority. DMacks (talk) 21:12, 9 May 2015 (UTC)
I was actually asking whether the calculate-from-formula is correct always, by chemistry. But ok.
Now when added to {Drugbox}, this would mean: ~every article is errormessaged because today all shown masses are entered. Maybe it is useful to maint cat those pages that show a diff between the two entered masses. -DePiep (talk) 22:00, 9 May 2015 (UTC)
Lots of cool physics would be possible if the mass of a chemical were based on something other than its constituent atoms. But for cases where someone had a reason to use some other value, the option of using the unified molecular_formula and then any arbitrary manually entered molecular_weight is there. DMacks (talk) 03:07, 10 May 2015 (UTC)
OK. I'll make the framework first, then come back here to fill in the details. -DePiep (talk) 07:58, 10 May 2015 (UTC)
See the next subsections. I want to do this right once and for all. -DePiep (talk) 20:09, 11 May 2015 (UTC)
DMacks pls note that I changed the priority (entered value overwrites), see below. -DePiep (talk) 20:19, 11 May 2015 (UTC)

The setup

This section might change following improvements (like a documentation). It does not follow common talkpage habit of adding comments and versions. Such regular discussions are in subsections below..

I am building {{Chem molar mass}} for this. It will be a general available template so it can be used in article texts too, and it will be build into {{Drugbox}}. It simply takes the molecular input by symbols. For example H
2O:

{{Chem molar mass|H=2|O=1}} → 18.02 g·mol−1

Build in {{Drugbox}}, the symbol inputs are passed-through.

  • |molecular_weight= in {{Drugbox}} allows a quantity to be entered by the article-editor (SI: quantity=number×unit). It overwrites a possibly calculated mass, to give the editor control over the value shown. It is passed through to |fixed= in {{Chem molar mass}}.
This opens the possibility that a {{Drugbox}} has two values for one data point: entered and calculated. These articles will be categorized for maintenance. The maintenance task is to remove the parameter |molecular_weight=input (and let the calculated quantity show), unless there is a reason to use that overwriting exception. With ~6000 {Drugbox}s in use, there could be thousands in this category. However, these are not in error and maintenance (emptying the category) can be done at ease (& with AWB).
  • Parameters |unit=, |round=, |ref=, |comment= are described in the documentation.
  • Once this template and its {{Drugbox}} application is stable and satisfying, the same setup will be introduced in {{Chembox}}.
  • In the {{Drugbox}} articles, no parameter changes are required, but the maintenance category might be emptied. Some parameters will be added (to use functionality of the calculator).
  • Issues are discussed below. -DePiep (talk) 20:09, 11 May 2015 (UTC)
Later descriptions are in the template /documentation. -DePiep (talk) 11:22, 26 May 2015 (UTC)

Issues

These issues have resulted in the Proposal. Please open/reopen new issues below.

Closed issues

Number handling

  • The output of {{Chem molar mass|H=2|O=1}} is (text) " → 18 g·mol−1" (from template if fixed:18.015 g·mol−1). It miss some decimals. One of the problems with molar mass are the numbers of decimals, but every element could have a precision of two decimals (except some of the last ones) Christian75 (talk) 20:34, 11 May 2015 (UTC)
The number in the demo is not exact or correct. I am going to ask about this shortly. -DePiep (talk) 20:44, 11 May 2015 (UTC)
Why round to 2 decimals always? -DePiep (talk) 21:23, 11 May 2015 (UTC)
Answer: explained in Molar_mass#Precision_and_uncertainties: it's lab habit, not the more theoretical perfection. Maybe full precision could be an extra option. Important: rounding should never add zero's.
There is not a theoretical perfection. It all depends on the distrubution of the isotopes, and as you can read at the section you linked to, it depends on a alot thing, e.g. destillation. Maybe the samples you buy from a chemical supplier would have 6 decimals, but you cant really be sure unless its a monoisotope you buy. Christian75 (talk) 08:09, 12 May 2015 (UTC)
OK, I get it. I meant to say: using and showing all decimals as defined by our source (could be IUPAC/CIAAW), pre-rounding=no laboratory rounding). If I understand this well: this same notion you make applies to elements with two published decimals (which are just as well sample-dependent). So, if we add the option |round=none the calculation uses & shows all decimals, handled correctly wrt precision (e.g. three for NaCl, see example below). -DePiep (talk) 08:24, 12 May 2015 (UTC)
Molar_mass#Molar_masses_of_compounds has an illustrating example, about rounding too:
M(NaCl) = [22.989 769 28(2) + 35.453(2)] × 1 g/mol = 58.443(2) g/mol
Let's forget about the bracketed uncertainities for now. It is clear that Cl has a lower precision (fewer decimals) than Na: 3 vs 8. So the result must use that lower number, because the precision of decimal 5, 6, ... in Na is not known for Cl. Adding them would suggest a precision not present. So decimal 4 is used for rounding decimal 3 (result being the .xx3), and next decimals are not used. A general rule thus would be: the result shows the lowest number of decimals in any of the base numbers. The discarded decimals ... Rounding is done as the final step, in the calculation (multiplying and adding) all decimals are used. (This is the way to round correctly: once, in the end). -DePiep (talk) 21:23, 11 May 2015 (UTC) -DePiep (talk) 08:40, 12 May 2015 (UTC)

Naming

From this start let's get the naming right. What to use?

I disapprove of the word "weight" (for the same). I do not fully grasp the diff between "molecular" and "molar" in this, and there is also the (omitted?) prefix "relative" showing up. Note that we add the unit (g/mol). Any wisdom in this? -DePiep (talk) 20:15, 11 May 2015 (UTC)

Moleculur mass are for molecules, molar mass are more genereal and can be used for ions and ionic compounds too. Christian75 (talk) 20:36, 11 May 2015 (UTC)
Supports using "molar mass" then. Could/should we extend this to the infobox label (change lefthand-column text or wikilink)? btw I discovered there is a long standing unresolved scientific dispute in there, so we might not be able to find a final conclusion here. -DePiep (talk) 08:00, 12 May 2015 (UTC)

Atomic weights numbers to check

We should check the relative atomic mass (atomic weight) numbers in {{Chem molar mass}}. Which list to use? -DePiep (talk) 20:39, 11 May 2015 (UTC)

For elements 84 (Po) and higher they are predictions. Does that require different treatment? -DePiep (talk) 20:39, 11 May 2015 (UTC)

I used the CIAAW (2013) numbers when available. For most radioactive elements (no stable isotopes), I've used the mass of the longest-living isotope (and so no decimals needed). See the {{Chem molar mass}} documentation. -DePiep (talk) 13:49, 25 May 2015 (UTC)

Uncertainty

Standard atomic weight is usually expressed with an uncertainty, as in 20.1797(6) for neon. It is possible to calculate the accumulated uncertainties for a compound correctly, and to show that in the result. However, at this moment there seems to be no use or need for this in wiki (no encyclopedic use). So for now, this feature will not be added. Come the need, we can add it. -DePiep (talk) 13:53, 16 May 2015 (UTC)

Proposal

I've prepared the {{Chem molar mass}} subtemplate to have molecular weight calculated from formula input. Basically, {{Drugbox}} articles now will use existing input like {{Drugbox|...|H=2|O=1}} to calculate the molecular mass (result: 18.015 g·mol−1).

See the new subtemplate's documentation for details, including the standard atomic weights used (CIAAW sourced). Main points:

  • Element symbols and additional parameters will be available in {{Drugbox}} for the editor to use: wrt calculation: |molecular_weight_round= ('no' or number; default=2), |molecular_weight_unit=, |molecular_weight_ref=; will show always: |molecular_weight=, |molecular_weight_comment=.
  • See Testcases.
  • When acceptable and stable, the same template will be added to {{Chembox}}.

I propose to add this to {{Drugbox}}. Comments? @DMacks and Christian75: ping. -DePiep (talk) 13:43, 26 May 2015 (UTC)

Defer briefly pending coordination with {{Chembox}} regarding if there is something gained by having a separate parameter for each element vs just parsing the whole formula in existing single-parameter string using Module:MolarMass. DMacks (talk) 19:39, 26 May 2015 (UTC)
@DMacks: What the fuck. Thanks for telling me this so timely. -DePiep (talk) 20:09, 26 May 2015 (UTC)
Huh? DMacks (talk) 20:14, 26 May 2015 (UTC)
Let me spell it out/spit it out: 9 May 2015 you ask this, I deliver into viable and tested and talked demos ready for deployment, and then you pop up with an immature trial? (labeled alpha by yourself no less within one day). I bet you'll steal the data I sourced and analysed too. (By the way, synchronising with {{Chembox}} I already cover, and is no reason to postpone this change). Why didn't you Talk? -DePiep (talk) 20:39, 26 May 2015 (UTC)
This reflects my initial responses to this surprising new development, my moments of frustration. After a good sleep, I look forward. I see that DMacks's module can have benefits, and so can be used when it is stable &tc. -DePiep (talk) 22:36, 30 May 2015 (UTC)
Question to DMacks. We do agree that this question is independent of the module discussion, I hope (or else please explain). Can you explain why or how this change should be deferred (=postponed) to be synchronised with a {{Chembox}} introduction? -DePiep (talk) 20:55, 26 May 2015 (UTC)
Yes, the module you are working on seems like a reasonable solution for "given each element in its own parameter, generate its mw", no objection to its use as such. But it requires passing formulas that way. I currently object to converting existing uses of |chemical_formula= because the alternative might be able to happen entirely "under the hood" without changes to existing uses. That's why (as I originally explicitly said) my concern was with the parameter-passing. DMacks (talk) 17:01, 27 May 2015 (UTC)
I align. For {{Drugbox}} we currently have two input options for the molecular formula (mf):
|chemical_formula={{Chem|H|2|O|1}} mf "hardcoded"
|H=2|O=1 mf "[chemical] symbol coded"
As we know, my new 'module' subtemplate {{Chem molar mass}} only calculates those symbol-entered mf's. The hardcoded ones are "fixed". I claim this is an improvement. In a future improvement (this is wiki), we could apply that function to deduct-mw-from-a-mf. So I say: let's do this, and improve later (possibly by the module you are working on).
Back to the core point: this change truly is an improvement. I mean to say: see your OP concern in the first place. -DePiep (talk) 21:44, 27 May 2015 (UTC)
I read in your opening post here that you suggest to calculate from symbol-input just as {{Chembox}} does. It does not say (to me) that the symbol-input is an issue in itself. Now adding the calculation this way (calculate from symbol-input only) would be an improvement always, coming from today's no-calculation. It does not require to change formula-input into symbol-input (but I agree it is there as an invitation). I find this no blocking reason, because symbol-input is still legal. If in the future we want formula-input only (as you aim at I understand), then we must edit articles anyway. Such a future requirement is not tied to this calculation introduction, but to that change of policy/documentation (deprecation of symbol-input). And so it must be handled when that topic arises. -DePiep (talk) 15:21, 28 May 2015 (UTC)

Molar weights: calculated or overwritten

Today Category:Chemical articles having calculated molecular weight overwritten was introduced (systematically filled by {{Drugbox}}). It lists articles that have molar weight input (=entered by article editor), so the infobox won't show calculated molar weight. As of now: {{Infobox drug}} solely lists 5160 articles (out of 5900=87%). -DePiep (talk) 00:20, 7 June 2015 (UTC)

Template edits 6 June 2015

Edits made to {{Infobox drug}}:

Talk: Template_talk:Infobox_drug#Add PLLR (US, pregnancy)
Request: Template_talk:Infobox_drug#Automating_molecular_weight_using_formula by DMacks
Proposal finalised: Template_talk:Infobox_drug#Proposal
Several parameters added, following subtemplate documentation
Maintenance: Category:Chemical articles having calculated molecular weight overwritten
Data pages are listed in Category:Chemical articles having a data page under "*" (distinct from {{Chembox}} listings under ABC).
Today five pages apply: Apomorphine (data page), Caffeine (data page), Cocaine (data page), Morphine (data page), Phencyclidine (data page)
  • Minor: PubChem data now shows linktext "CID: 4091" not "CID 4091" ('CID' is not part of the id number).
The first three are towards alignment with {{Chembox}} when possible.
checkY processing. -DePiep (talk) 12:22, 6 June 2015 (UTC)
 Done. -DePiep (talk) 12:34, 6 June 2015 (UTC)

Great! Real Life will (continue to) consume me for the next two days (sorry for suddenly dropping off). DMacks (talk) 06:52, 7 June 2015 (UTC)

Thanks. IMO you did not promise any activity to me, so nothing is dropped. This being wiki, edit when you like. -DePiep (talk) 21:03, 7 June 2015 (UTC)

Discussion about data pages

A discussion was started at WP:Chemistry#Data_pages about what to do with data pages like Ammonia (data page) for Ammonia (more listed here). -DePiep (talk) 10:27, 8 June 2015 (UTC)

Morphine (data page) listed at Redirects for discussion

An editor has asked for a discussion to address the redirect Morphine (data page). Please participate in the redirect discussion if you have not already done so.

Duration of effect

Currently we have "onset of action" and "half life". Duration of effect would also be useful. For example the duration of effect of cocaine is 5 to 90 minutes depending on how it is used. This information is very useful for many substances. Doc James (talk · contribs · email) 11:11, 15 June 2015 (UTC)

That would be (I suggest) |duration_of_effect= showing like:
Duration of effect     5 to 90 minutes
Positioned right below |onset= and |elimination_half-life=. What should the LH text link to? See testcases10. I have no opinion on usefulness of this param. -DePiep (talk) 08:03, 16 June 2015 (UTC)
How about to Duration_of_action? We can call it "duration of action"
This is of great importance for opioid overdoses as one need to take into account the duration of the opioid taken versus that of naloxone. Doc James (talk · contribs · email) 12:41, 16 June 2015 (UTC)
Duration of action is OK with me, done, see tests. Parameter name follows? (I'd say yes to help fellow editors). -DePiep (talk) 12:58, 16 June 2015 (UTC)
What exactly do you mean by "Parameter name follows"? Doc James (talk · contribs · email) 13:36, 16 June 2015 (UTC)
If the visible text is "Duration of action", the parameter name should preferably be |duration_of_action= to help any article editor looking to edit that value. Less searching, ease of mental steps. The parameter spelling is alike other {Drugbox} parameter spellings (use lowercase, underscore). -DePiep (talk) 13:45, 16 June 2015 (UTC)
I suspect the duration of effect would require clarifications, like dose, age, empty/full stomach, possibly body mass. If this is indeed so, then better to give that in the article's body. Brandmeistertalk 17:11, 16 June 2015 (UTC)
Brandmeister, do you mean the parameter should no be in the infobox at all? If so, isn't that argument valid for many more drug parameters?. I thought we had a general disclaimer like "data is not exact in medicine"? And, usually those details are in the source. -DePiep (talk) 09:20, 17 June 2015 (UTC)
Basically I don't object, my concern was possible vagueness. Ranged average values, like 5-10 minutes, have their own merits. Brandmeistertalk 09:28, 17 June 2015 (UTC)
So for cocaine it is 5 to 90 minutes. Morphine is 3 to 7 hours. Etc. The same applies to half life and that is in the infobox and not presented as a range. There are well sources ranges for duration of action. Warfarin is longer than dabigatran for example (thus more problems with forgetting a dose). Doc James (talk · contribs · email) 09:30, 17 June 2015 (UTC)
I think Brandmeister means "imprecision" for "vagueness" (which I think makes it a correct statement). Again, that may be true for many medical and biological parameters. But I don't think we should remove them for that reason (or prevent this one parameter). Interesting is the dewiki option, to add a specifier template to enter all data systematically (from this talk): Infobox input
| ToxDaten = {{ToxDaten |Typ=LD50 |Organismus=Ratte |Applikationsart=i.v. |Wert=16 mg·kg<sup>−1</sup> |Bezeichnung= |Quelle=<ref name="Sigma" /> }}
→ 16 mg·kg−1 (LD50, Ratte, i.v.)[4]
However, that is available in our future only.
Meanwhile, I 'abuse' the latest opening statement by Brandmeister to mean support addition by a milimeter ;-). Note that this |duration_of_action= has free text, reproduced unedited by {Drugbox}, so one can add any info as desired. -DePiep (talk) 10:58, 18 June 2015 (UTC)
Is this worth adding to Chembox as well? Sizeofint (talk) 14:45, 18 June 2015 (UTC)
Few {Chembox} articles dive into pharmacology. Maybe add the whole set of 7? -DePiep (talk) 17:16, 18 June 2015 (UTC)
That isn't a bad idea. I think {Chembox} is only missing |duration_of_action= and |onset=. Also, {Chembox} has |metabolites= but {Drugbox} does not. Can this be added to {Drugbox} as well? Incidentally, duration of action is showing up fine but when previewing an edit Error in template * unknown parameter name (Template:Infobox_drug): 'duration_of_action shows at the top of the page.
Quick re's: 1. just added, see {{Chembox}}/doc bottom navbox: top row has link to "All parameters" for easy param search.
2. That red line says you entred an unknown param in the outer {{Chembox}} param list (not within a |SectionN= subtemplate).
3. I meant the set of
 | bioavailability   = 
 | protein_bound     = 
 | metabolism        = 
 | onset             = 
 | elimination_half-life = 
 | duration_of_effect = 
 | excretion         = 
 | routes_of_administration =
into {{Chembox Pharmacology}} (I'd expect)
4. Metabolites is in there btw. In general, please start a new thread here for any new (set) of requests/proposals. CAnnot mix this all together. End of quick reply. -DePiep (talk) 18:40, 18 June 2015 (UTC)
The red line is problem with {Drugbox} not {Chembox}. Try previewing an edit on Cocaine and you will see the error. Sizeofint (talk) 19:20, 18 June 2015 (UTC)
ThatMy quickness was useless! You can ignore that red message and save, it shows all right. Would you propose the {{Chembox}} changes at that talkpage? -DePiep (talk) 19:46, 18 June 2015 (UTC)
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